Seungsoo Kim

Kim Lab at UC Irvine Visit the post for more.

The Kim Lab (sskimlab.org) at UC Irvine is recruiting motivated grad students interested in uncovering how transcriptional regulators direct cell fates. We accept students through the CMB (cmb.uci.edu) and MCSB (ccbs.uci.edu/education/mcsb/) PhD programs. Please share with prospective grad students!

👀Next Wednesday, Oct 22nd, at #FragileNucleosome seminar, we are excited to host @alicelaigle.bsky.social and @seungsookim.bsky.social to tell us about amazing work they are doing!
🗓️Register here for upcoming session and the entire series:
us06web.zoom.us/webinar/regi...

How do non-coding variants in enhancers lead to disease? Happy to share our recent work, led by @ewholling.bsky.social, in which we discovered that poised chromatin sensitizes enhancers to aberrant activation by non-coding mutations, contributing to disease. www.biorxiv.org/content/10.1... 1/

Promoter strength and position govern promoter competition Competition between promoters within a shared regulatory landscape has been implicated in development and disease, but the determinants of promoter competition have not been systematically studied. He...

www.biorxiv.org/content/10.1...

Naz's preprint is out and she is looking for a postdoc!
🔬
Enthusiastic. Smart. Hard working. Top lab citizen. Explain models of transcription with Oscar-deserving gestures. Hire Naz!

Junior / Assistant Specialist: Kim Lab, Developmental & Cell Biology University of California, Irvine is hiring. Apply now!

I am hiring for a research technician role in my new lab at UC Irvine studying how transcription factors control cell identity. If you know any graduating undergrads or postbacs looking for a position, please spread the word! Apply by May 9 for full consideration. recruit.ap.uci.edu/JPF09594

DNA-guided transcription factor interactions extend human gene regulatory code - Nature A large-scale analysis of DNA-bound transcription factors (TFs) shows how the presence of DNA markedly affects the landscape of TF interactions, and identifies composite motifs that are recognized by ...

A tour de force study from Taipale&Yin labs. It expands the vocabulary of the Regulatory Code by adding 1131 TF:TF composite motifs that are different from the individual TF motifs. The new composite motifs are enriched in cell-type specific elements and active in vivo
www.nature.com/articles/s41...

My alma mater, the University of British Columbia, Dept of Medical Genetics, is hiring for a tenure track junior faculty position specializing in chromatin regulation / gene regulatory mechanisms. Beautiful city and vibrant epigenetics research. Please share!

medgen.med.ubc.ca/assistant-pr...

Map of Stand Up for Science events, with official SUFS events in Red and solidarity events in Blue

WHERE WILL YOU BE ON MARCH 7TH!?

Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one!

#standupforscience2025

Before I start, let me thank the brave folks within NIH who have shared information, hints, and other materials that have helped me sort this out. I don’t know most of your names and, even if I did, no one would ever hear them from me.

So here is what appears to be going on…

1/n

Judge Temporarily Blocks Trump Cuts to Medical Research Funding (Gift Article) A coalition of 22 attorneys general sued the federal government, claiming that the $4 billion in cuts would “grind to a halt” studies on cancer, heart disease and other conditions.

Good news (for now) www.nytimes.com/2025/02/10/u...

Thanks, you too!

Open Rank Faculty Position in David Geffen School of Medicine at UCLA University of California, Los Angeles is hiring. Apply now!

Friends, we have a school-wide search for an open rank faculty as mentor professor. It is a unique position that can be hired in a variety of departments across the school. Please check it out and share widely.

recruit.apo.ucla.edu/JPF10062

Just received notice that my NIH study section next week has been cancelled. It has nothing to do with DEI and will have a negative impact on critical cancer research.

NIH council meeting (NIDCR)scheduled for today, where our R01 grant (3rd percentile) was supposed to be discussed, was postponed indefinitely as a consequence of Trump's executive order which ordered pausing of all communications from all federal agencies. Not good.

NIH In Your State - United For Medical Research Select a state on the map to see the impact of NIH funding across America.

I just reached out to my senators about the NIH situation. If you need to find out how much impact NIH has in your state in terms of dollars in and their economic impact here's a link: www.unitedformedicalresearch.org/nih-in-your-...

A great opportunity to start your own research group

@pasteur.fr in Developmental Biology👇
research.pasteur.fr/fr/call/call...

Multiscale footprints reveal the organization of cis-regulatory elements www.nature.com/articles/s41...
▶️Footprints of DNA–protein interactions from bulk & single-cell ATAC-seq ⤵️
▶️Deep learning to infer transcription factor and nucleosome binding
▶️Age-associated reduction of nucleosome footprints

Thank you!

Kim Lab at UC Irvine Visit the post for more.

Hello Bluesky friends! I am a #newPI starting at UC Irvine in April, interested in gene regulation and functional genomics in stem cell models of development (esp neural crest). We are hiring at all levels – please reach out/spread the word! sskimlab.org