Brady Lab

Human-specific gene expansions contribute to brain evolution A complete human genome and functional modeling in zebrafish pinpoint gene expansions that may underlie the evolutionary innovations of the human brain.

So excited to see this paper out in Cell from the group of my good friend @mydennis.bsky.social It's been so exciting to see this story progress progress. www.cell.com/cell/abstrac...

Conservation and divergence of regulatory architecture in nitrate-responsive plant gene circuits Gene circuits that control transcriptional regulation of nitrate-responses have similarities and differences, despite the equivalent effects of nitrogen on

Excited that our paper with @bradylabs.bsky.social on conservation and divergence in nitrogen regulatory networks is finally published. This was a fun & rewarding collaboration that will continue in new projects to engineer 🍅 N responses academic.oup.com/plcell/artic...

Conservation and divergence of regulatory architecture in nitrate-responsive plant gene circuits Gene circuits that control transcriptional regulation of nitrate-responses have similarities and differences, despite the equivalent effects of nitrogen on

At long last, our paper on conservation and divergence of a nitrogen circuit upstream of NLP6/7 &NIR1 in Arabidopsis and tomato is published! It's an exciting combo of whole plant, in vitro, protoplast and systems bio approaches: tinyurl.com/nitrogencirc... @gozdedemirel.bsky.social

This is my all-time favorite meeting. The best plant developmental biology meeting imo.

Single-cell transcriptomics reveal how root tissues adapt to soil stress Nature - Single-cell RNA sequencing and spatial transcriptomic approaches reveal major expression changes in outer root cell types when grown in soil versus gel conditions, and also uncover how...

I'm so very excited to see this out - a single cell and spatial transcriptomic analysis in the rice root reveals mechanisms by which roots can respond to different below-ground growth conditions - including compaction. Congratulations to everyone for persisting in difficult times. rdcu.be/ej8Ui

Congratulations!

Postdoctoral Researcher- Brady Lab University of California, Davis is hiring. Apply now!

We have a postdoc position that just opened up in the Brady lab on reprogramming tomato root system architecture in response to changes in nutrient availability - please consider applying! recruit.ucdavis.edu/JPF07095

Check out this exciting GRC on plant single cell bio! I’ll be speaking about our collaborative @hfspo.bsky.social moss project with @tevavernoux.bsky.social Yoan Coudert, Lidor Shara-Moshe, Richard Smith, Javier Jauregui-Lazo, Laure Mancini and more!

Apoplastic barriers are essential for nodule formation and nitrogen fixation in Lotus japonicus Establishment of the apoplastic root barrier known as the Casparian strip occurs early in root development. In legumes, this area overlaps with nitrogen-fixing nodule formation, which raises the possi...

Finally!
Im so excited to present to culmination of many years of work from the fantastic Defeng Shen and some great collaborators. For details, I have made a digested thread below, but if you are more interested feel free to reach out (and read the paper of course).
www.science.org/doi/10.1126/...

Plz Repost. We @slcuplants.bsky.social @uniofcam.bsky.social are looking for a postdoc with proven protein biochemistry & cell biology expertise & strong interest in plant processes targeted by Phytophthora effectors. (apply before 2 April) [Image: Alex Guyon]

www.jobs.cam.ac.uk/job/50570/

Crystal Rogers Honored as Chancellor's Fellow Associate Professor Crystal Rogers is one of eight faculty members who comprise the newest class of UC Davis Chancellor’s Fellows, given to early career academics doing exemplary work in their fields.

Huge thank you to Chancellor May and our wonderful @ucdavis.bsky.social donors for choosing me as a Chancellor’s Fellow! The UC Davis SVM did a lovely write up if you are interested in learning more about me and this award! www.vetmed.ucdavis.edu/news/crystal...

Many government employees who enable our research are not forward-facing, and don't necessarily see our support and commitment to them. Consider reaching out to them personally, and letting them know that you support them.

I've had conversations in the last day with NSF&USDA employees on my research, outreach & permits. I am in awe of their efforts, above&beyond, to enable our research community, to push things through, despite not knowing if they will have a job next week. They are TRUE community providers & heroes.

Contact me if you can't access it.

German and US flags

To US colleagues who have lost or are in imminent danger of losing their jobs: please DM whether we can accommodate your research.

New round of the Lise Meitner Excellence Program for tenure track group leaders in @maxplanck.de institutes opened today -- please consider applying! The program aims to recruit and promote exceptionally qualified female scientists.
Because diversity increases excellence!
www.mpg.de/lise-meitner...

PhD Research Fellow in functional genomics (274518) | University of Oslo Job title: PhD Research Fellow in functional genomics (274518), Employer: University of Oslo, Deadline: Friday, February 28, 2025

We have a PhD position available at the Department of Biosciences, University of Oslo to work on peptide signaling in plants and insects. Please share.

www.jobbnorge.no/en/available...

Does anyone have experience with low-input high-throughput (96 well plate) RNAseq library preparation from plants (bonus points if it is with plant roots...)

I'm happy to announce a postdoctoral position is available in my lab. We have lots of great data to analyze with respect to transposons & epigenetics and cool biological questions to answer.
Please reskeet and share.

Dennis lab members

Hello bluesky friends! I'm excited to introduce myself. I go by (mee-gun) and am a proud #firstgen college grad that grew up in the midwest. My lab @UCDavis studies genetic drivers of human traits, evolution, and diseases, with an emphasis on neurodevelopment and complex variation. 1/10 (buckle up)

Reminder #jobalert for a starting postdoc or PhD position (for someone with strong ML background)!
Joint project with Gregoire Montavon’s lab at #BIFOLD @xtraexer.bsky.social -
explainable AI for self supervised LLMs in gene regulation. Apply until Dec 13!

www.bifold.berlin/about-us/opp...

I am so excited to share Dr. C Manzano’s work: she demonstrates the developmental timeline, function and genetic regulation of the polar lignin cap in the tomato root. It functions as a distinct intercellular barrier from the Casparian strip and is repressed in inner layers. rdcu.be/d10Pd

I am really proud to share our study on microbes, Striga and sorghum is now online in Cell Reports! doi.org/10.1016/j.ce... and the press release is here: biology.ucdavis.edu/news/soil-mi... This was an epic effort led by the incredible Dorota Kawa, +B. Thiombiano, H. Bouwmeester, J. Raiijmakers...

I've got a postdoc position open in my lab. Do you work on moss, single cell transcriptomics or plant developmental genomics? Consider applying for this position - more here:
recruit.ucdavis.edu/JPF06360