Pengyao Jiang

Scikit-bio: a fundamental Python library for biological omic data analysis - Nature Methods Nature Methods - Scikit-bio: a fundamental Python library for biological omic data analysis

The scikit-bio paper in online in Nature Methods! Many thanks to our collaborators, community contributors and reviewers! We couldn’t have done it without you. www.nature.com/articles/s41... #Bioinformatics #OpenSource

The discovery and patterns of the underlying long-standing mild-effect mutator alleles in S. cerevisiae populations Most mutations are neutral or deleterious, and mutator alleles that increase the mutation rate of an organism are considered rare and short-lived. Here, we report a genomic signature consistent with t...

New preprint with @pyjiang.bsky.social and @kelleyharris.bsky.social! The discovery and patterns of the underlying long-standing mild-effect mutator alleles in S. cerevisiae populations www.biorxiv.org/content/10.1...

Homepage - Population, Evolutionary, and Quantitative Genetics Conference Visit our website to learn more.

Save the date! #PEQG26 June 9-12 2026 in Asilomar, CA. Happens only every 2yrs, but is my favorite conference. Full website coming soon, and registration and abstract submission opens November 14, but I'm allowed to tease that keynotes will be @jnovembre.bsky.social @jennytung.bsky.social and me!

Our annual symposium is now open for registration! This year’s theme is Unicellular Diversification of Cell Types and Division. Abstract closes on Oct 1st.

Poster advertising CanFunNet and the plenary speakers/

Abstract submission is still open until June 13th for CanFunNet's virtual meeting!

Register here: conference.has.uwo.ca/Register/def...

What

NSF, NASA and NIH budgets per year, inflation adjusted from 2000-2025 along with the proposed cuts. NSF includes research component only. Massive cuts across all sectors, well below support spanning 25 years.

How bad will it be? Catastrophic.

Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come.

But, this is the WH's *proposed* budget.

Speak up now before it is too late.

(inflation adjusted $-s below)

Estimates for # of people involved in NSF activities

From over 300k to less than 100k. A picture of smaller, reduced science.

"If the proposal is enacted, Americans today and tomorrow will be sicker, poorer, and die younger”
an $18 Billion cut
Only 3 NIH Institutes will remain in place, and even they will have their funds markedly reduced
www.statnews.com/2025/05/30/n...

Trump team pauses new student visa interviews as it weighs expanding social media vetting It’s the latest salvo against universities, many of whom rely heavily on foreign students for funds.

The Republican administration has halted all student (and postdoc etc) VISA interviews.

I've written a lot about soft power here. The attacks on foreign students in the US not only undercuts the funding stream for US universities; they hemorrhage US soft power.

Trump Administration Says It Is Halting Harvard’s Ability to Enroll International Students

Another incredibly shameful move from the Trump administration. Upending the lives of so many young people to score cheap political points is absolutely unconscionable.

www.nytimes.com/2025/05/22/u...

. @pnas.org just published the final version of our manuscript on how generation time and effective population size interact to shape vertebrate germline mutation rates, led by Luke Zhu and Annabel Beichman: www.pnas.org/doi/10.1073/...

“Cutting basic science doesn’t save money.”

A screenshot of the termination notice showing "Outstanding Investigator Grants"

A screenshot of the termination notice with "This award is terminated effective the date of this award, due to unsafe antisemitic actions that suggest the institution lacks concern for the safety and wellbeing of Jewish students." highlighted

Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab

Trump’s war on science is an attack against anyone who has ever loved someone with cancer.

The American people do not want us to slash cancer research in order to give more tax breaks for billionaires.

Lux Capital providing funding opportunities for academic biomedical research aligned with interests 👏

www.luxcapital.com/news/our-hel...

svglite 2.2.0 A new release of svglite has arrived, and with it full support for all the latest capabilities of the R Graphics Engine. Further, it finalizes the new approach to handling web fonts and font embedding...

I am excited to share a new version of svglite for #rstats with the world. It includes support for all the new features in the graphics engine as well as providing a more powerful and polished experience for embedding web fonts in the file.

Read all about it her:

If you care about the NSF and science, now is the time to make your voice heard!

The evolution tri-societies are running a Week of Action for NSF! We MUST make some noise -join us!!

@sse-evolution.bsky.social members will see the below email in their inbox today, spread the word!

Pls RT!

EU augments opportunities for scientists around the world to launch or re-launch their careers in Europe.

Rapid Response Bridge Funding Program In the face of recent abrupt shifts in federal funding for education research, including large-scale terminations of National Science Foundation (NSF) research grant awards, we have developed a rap...

The Spencer Foundation is offering rapid response bridge funding for those who lost NSF research grants.

www.spencer.org/grant_types/...

Deep cuts to EPA, CDC, FDA, NIH, NSF, NOAA, USDA, education & more will damage health and shorten life spans, especially w/ cuts to healthcare for those w/ limited means.

Is this the goal, to reduce "entitlements" by killing people? Well, it sure won't make the wealthy any more comfortable.

So Happy for the warm welcome or our PopGen bookclub! Each month, at IBE, we review a new chapter of @gcbias.bsky.social book, which is totally open-source! We encourage you to take a look at it! Link: github.com/cooplab/popg...

Trump proposes massive NIH budget cut and reorganization Will Republican-led Congress support a 44% decrease for world’s largest medical research funder?

Trump proposes massive 44% NIH budget cut and reorganization | Science | AAAS www.science.org/content/arti...

NSF Grant Termination Information Collection Form Please use this form to submit information identifying specific NSF grants that have been cancelled for any reason after January 20, 2025. We are tracking these grants to increase transparency, organize affected PIs, and facilitate responses, including via litigation. Please share the form as widely as possible with your networks. We are actively building a pipeline to organize these terminations and will soon have a tracker akin to our NIH grant tracker at https://airtable.com/appjhyo9NTvJLocRy/shrNto1NNp9eJlgpA WE WILL NOT DISCLOSE THE IDENTITY OF ANYONE WHO USES THIS FORM TO PROVIDE INFORMATION. We will keep your identity confidential. These resources are maintained by Noam Ross of rOpenSci and Scott Delaney of the Harvard T.H. Chan School of Public Health, with input and support from additional volunteers. For any questions, please contact Scott Delaney on Signal (sdelaney.84). THANK YOU FOR YOUR ASSISTANCE!

🚨Report your NSF grant terminations! 🚨

We are starting to collect information on NSF grant terminations to create a shared resource as we have for NIH. The more information we collect, the more we can organize, advocate, and fight back! Please share widely!

airtable.com/appGKlSVeXni...

Application deadline extended to Apr 15 for this summer's #Yeast #Genetics & #Genomics course at @cshlaboratory.bsky.social July22 - Aug12! Get a comprehensive education in all things yeast, from classical genetics through up-to-the-minute genomics. Don't miss out!
meetings.cshl.edu/courses.aspx...

Chilling to see this list of terminated NIH grants. Research on Alzheimer's, HIV, rare diseases, vaccines -- gone. Cancer centers closed, training grants & fellowships terminated. Young scientists stranded. Patients waiting for treatments that'll never come. Just sad.

taggs.hhs.gov/Content/Data...

Graduate Reductions Across Biomedical Sciences (2025)

There’s a google doc trying to keep track of funding/grad school admission/hiring freezes & status please share 🧪 docs.google.com/spreadsheets...

Who funds biomedical research? @nature.com
www.nature.com/articles/d41...

a cartoon of homer simpson holding a card ALT: a cartoon of homer simpson holding a card

Bluetorial:

The announcement to move scientific review out of the institutes and centers into the Center for Scientific Review (CSR) and its potential consequences

#standupforscience2025 map of events

Science impacts communities nationwide. Ongoing efforts by the WH to dismantle American leadership in science will ripple outwards: risking lives, well-being, and the economy.

Stand Up For Science - March 7, 2025
#standupforscience2025 standupforscience2025.org/local-event-...