Richard J Miller

The age of animal experiments is waning. Where will science go next? Advances in organ and computer models are raising the prospect that some animal experiments could be eliminated. But there are still huge hurdles to overcome.

Ending animal experimentation is no longer a minority opinion.

www.nature.com/articles/d41...

COMP360 Psilocybin for Treatment-Resistant Depression Achieves Primary Endpoint in Phase 3 Trial | Psychiatric Times Phase 3 trial shows COMP360 psilocybin rapidly reduces treatment-resistant depression symptoms with durable effects and good safety, as Compass moves toward FDA review.

Pushing forward with psilocybin for depression,

www.psychiatrictimes.com/view/comp360...

The pill of the century: a single trip with LSD reduced anxiety for three months, according to a clinical study One supervised LSD-based dose cut anxiety in a JAMA trial, with benefits lasting up to 12 weeks for many patients.

Does LSD reduce anxiety?

www.ecoticias.com/en/the-pill-...

How Animal Suffering Can Ruin Lab Experiments How Animal Suffering Can Ruin Lab Experiments: Larry Carbone on his 3 greatest revelations while writing "The Hidden Lives of Lab Animals."

Why animal suffering invalidates most experiments.

nautil.us/how-animal-s...

Why is NIH still funding animal testing when it announced last year it was phasing it out Years of pressure from taxpayers, lawmakers, and animal advocacy groups have led to multiple federal agencies banning animal research involving dogs and cats.Th

NIH needs to stand by its promises to end animal research.

wjla.com/features/i-t...

Psychedelics Space at a ‘Tipping Point’ as Compass, Definium Gear Up To File for Approval With Lykos’ regulatory failure now squarely in the rearview mirror, Compass Pathways and Definium are leading what one analyst suspects will be “a very big year for psychedelics.”

2026 may be a big year for psychedelics.

www.biospace.com/drug-develop...

New Theories and Findings From The Frontier of Ibogaine Research - Lucid News After publishing a new study investigating synthetic analogs for iboga molecules, scientist and co-founder of Gilgamesh Pharmaceuticals, Dalibor Sames, decided to take the compound he has described as...

Ibogaine shows new therapeutic promise.

www.lucid.news/new-theories...

OHSU board contemplates closure of primate research center; its scientists plead for support Scientists at the Oregon National Primate Research Center say their work is driving critical medical advances. But leadership at the federal level has questioned the value of the research model, and c...

It's time to end research that uses primates.

www.opb.org/article/2026...

Can alternative models really replace animal testing? As the FDA shifts toward nonclinical methods, scientists weigh whether alternative technologies can match the predictive power of animal studies.

Can animal testing be eliminated? The answer is yes.

www.drugdiscoverynews.com/can-alternat...

Mycologists Discover "New" Psychedelic - A Rich Life When undercooked, the mushroom known in PNG, the Philippines and Yunnan, China is associated with the appearance of "little people".

Nobody knows (yet) what makes these mushrooms hallucinogenic.

arichlife.com.au/mycologists-...

LSD found to reduce anxiety symptoms in study as researchers seek path to medical approval | Milwaukee Independent

The promise of psychedelics.

www.milwaukeeindependent.com/newswire/lsd...

United Kingdom presents historic strategy to eliminate animal experimentation The British government sets concrete deadlines and allocates 75 million pounds to develop technological alternatives to replace animal testing.

Ending animal experimentation in 2026.

www.animanaturalis.org/n/47030/unit...

Scientists recover RNA from an extinct animal for the first time Scientists successfully extract RNA from a 130-year-old Tasmanian tiger, thylacine, revealing how its genes functioned before its extinction.

Can extinct animals live again?

www.earth.com/news/scienti...

Scientists Released Caged Mice Into The Wild, And an Incredible Thing Happened Dozens of laboratory mice allowed to roam a large outdoor enclosure returned to a typical level of mouse anxiety after just one week, researchers observed, suggesting that 'rewilding' may prevent lab-...

Mice were never meant to live in laboratories.

www.sciencealert.com/scientists-r...

RFK Jr. says he'll work with federal agencies to wind down animal testing Animal rights groups celebrate, but the Trump administration is light on specifics about phasing out federally funded medical testing on animals.

Government to wind down animal experimentation.

www.cbsnews.com/news/rfk-jr-...

CDC to end animal testing that will impacts hundreds of experiments In a major policy reversal, the Trump administration has ordered the CDC to cease all scientific research involving primates, accelerating its effort to end animal testing.

CDC to end animal testing.

www.dailymail.co.uk/health/artic...

A moonshot for animal-free European health research With 95 percent of drugs failing clinical trials, it’s clear that a new approach is needed. Let’s not miss this chance to invest in a new kind of science.

A moonshot for animal-free European health research .

www.politico.eu/sponsored-co...

Psychedelics research in rodents has a behavior problem Simple behavioral assays—originally validated as drug-screening tools—fall short in studies that aim to unpack the psychedelic mechanism of action, so some behavioral neuroscientists are developing…

Trying to understand how psychedelics work using mice is a ridiculous idea.

www.thetransmitter.org/psychedelics...

From today's (Dec 17th) Financial Times

Letter: Phasing out animal testing can give western biotechs a real edge

From Simon Burns, Founder & CEO, Vial

Mycologists Discover "New" Psychedelic - A Rich Life When undercooked, the mushroom known in PNG, the Philippines and Yunnan, China is associated with the appearance of "little people".

Has a new psychedelic been discovered?

arichlife.com.au/mycologists-...

Organoids are the future but raise their own ethical issues.

theconversation.com/mini-brains-...

Ending research on monkeys can't come to soon!

www.science.org/doi/epdf/10....

Mitigating Bias Toward Animal Methods During NIH Grant Review Physicians Committee experts and leaders of the Coalition to Illuminate and Address Animal Methods Bias (COLAAB), an international collaboration of researchers and advocates dedicated to exploring and...

Do you want an NIH grant? Stop working on animals!

www.pcrm.org/news/good-sc...

Are Animals Out? How NAMs Are Changing the Rules of the Game A coordinated national effort is emerging to bring alternatives to animal testing into routine preclinical use, backed by a fresh FDA roadmap and a global coalition of scientific and industry partners...

Biomedical research.Animals are out!

www.biospace.com/fda/are-anim...

Exclusive: CDC to end all monkey research Studies related to HIV and other infectious diseases will be phased out, sources say; fate of the agency's animals remains unclear

The beginning of the end of animal experimentation.

www.science.org/content/arti...

Psychedelics Made Me Christian A few years ago, following a few decades wastefully spent consuming no other mind-altering substance than alcohol (which I quit for good in 2020), I began to experiment with psilocybin.

Psychedelics.Just in time for Christmas.

www.compactmag.com/article/psyc...

How the Right Coopted Psychedelics What was once a signature party favor of the left has been subsumed by optimization-obsessed conservatives. How did we get here?

The universal appeal of psychedelices.

www.gq.com/story/how-th...

Whole-cortex in situ sequencing reveals input-dependent area identity - Nature BARseq interrogates the expression of 104 cell-type marker genes in 10.3 million cells over nine mouse forebrain hemispheres to reveal the role of peripheral inputs on cortical area development.

Mouse eyes horror! Investigators blind mice in their experiments.
Why are people allowed to do things like this?

www.nature.com/articles/s41...

Britain's Bold Plan to End Animal Testing Gains Unlikely Unity On a gray November morning in London, ministers, scientists, and animal welfare advocates did something rare: they all applauded the same announcement.

Getting together to end animal testing.

scienceblog.com/britains-bol...

Victory for Monkeys! The Netherlands to Cut Funding for Cruel Experiments The Netherlands will stop funding experiments on monkeys at the Biomedical Primate Research Centre and invest in humane, non-animal research. A breakthrough for monkeys, humans, and science.

One small step in reducing cruelty to animals.

www.peta.org.uk/blog/netherl...