Amanda Randles  ๐Ÿงชโš›๏ธ ๐Ÿ‘ฉโ€๐Ÿ”ฌ's Avatar

Amanda Randles ๐Ÿงชโš›๏ธ ๐Ÿ‘ฉโ€๐Ÿ”ฌ

@profamandarandles.bsky.social

Director of the Duke University Center for Computational and Digital Health Innovation. Alfred Winborne Mordecai and Victoria Stover Mordecai Associate Professor of Biomedical Engineering. Research in HPC and digital twins for health.

3,536 Followers  |  8,149 Following  |  148 Posts  |  Joined: 14.11.2024  |  2.0378

Latest posts by profamandarandles.bsky.social on Bluesky

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Excited to share a new Communications of the ACM article highlighting our work on vascular digital twinsโ€”using millions of simulated heartbeats and wearable data to help predict heart issues long before symptoms appear. ๐Ÿ”—https://duke.is/cacm25

13.11.2025 21:30 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Join us tomorrow for Dr. Michael Rubinsteinโ€™s virtual talk, โ€œThe Loops of Life.โ€ Explore how molecular size, topology, and interactions shape polymers.

Register: duke.qualtrics.com/jfe/form/SV_...

@dukeengineering.bsky.social @dukeubme.bsky.social

06.11.2025 03:16 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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At the Center for Computational and Digital Health Innovation, weโ€™re advancing technology with purpose.
Proud to spotlight Cameron Kim, whoโ€™s shaping the future of ethical digital health innovation and preparing the next generation of leaders.
comphealth.duke.edu/featured-res...

15.10.2025 16:02 โ€” ๐Ÿ‘ 6    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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So proud of the Randles Lab team for their fantastic presentations at #BMES2025โ€”from cardiovascular digital twins and wearable-driven modeling to cellular biomechanics. Exciting to see their work pushing the boundaries of computational and digital health. #DukeBME #ProudPI

15.10.2025 13:52 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐ŸงชI didnโ€™t get to post about this earlier, but I recently had the honor of giving the opening keynote at IWOMP 2025. I had a great time talking with the MPI and OpenMP community about opportunities to bring HPC advances to health and scale vascular digital twins. #HPC #OpenMP #MPI #DigitalTwins

13.10.2025 17:24 โ€” ๐Ÿ‘ 7    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Taking the pulse on less computationally intensive cardiac digital twins Highly detailed simulations of the coronary artery only need one to two heartbeats to calibrate, rather than the standard five-plus

Led by Nusrat Sadia Khan, our team showed that cardiac digital twins can reach hemodynamic convergence in just 1โ€“2 heartbeats, cutting computational costs and enabling real-time, scalable cardiovascular modeling.

Scilight: www.aip.org/scilights/ta...

Paper: pubs.aip.org/aip/pof/arti...

13.10.2025 17:06 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Great to join the 2nd Annual Duke Summit on AI for Health Innovation, hosted by @dukeaihealth.bsky.social, the Center for Computational and Digital Health Innovation, and DCRI.

Exciting discussions on AI, digital twins, and the future of healthcare. #AIforHealth #DigitalHealth #HPC #Innovation

13.10.2025 16:50 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Itโ€™s #BMES2025! The Randles Lab is sharing new work on digital twins for heart failure, HRV-based model reduction, cellular heterogeneity, and APR modeling of RBCโ€“cancer interactions. Stop by the Duke booth to learn about our Center for Computational and Digital Health Innovation! #DigitalHealth

08.10.2025 04:01 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Aristotle Martin Receives Honorable Mention for 2025 George Michael Memorial HPC Fellowship - Center for Computational and Digital Health Innovation Congratulations to Center member Aristotle Martin on receiving an honorable mention for the 2025 ACM-IEEE CS George Michael Memorial HPC Fellowships. The George Michael Memorial Fellowship honors exce...

Congrats to Randles Lab PhD student Aristotle Martin on being named an Honorable Mention for the ACM-IEEE CS George Michael Memorial HPC Fellowship! A well-deserved recognition of his innovative cancer cell modeling researchโ€”proud to see him celebrated.

comphealth.duke.edu/news/aristot...

02.10.2025 03:44 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks for having me! Had such a great time discussing HPC in Health with this community.

02.10.2025 03:07 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Join us Wed, Oct 2 @ 3 PM ET for the Center for Computational and Digital Health Innovation + Duke Quantitative Biodesign Virtual Seminar! Fabian Theis (Helmholtz Munich/TUM) will speak on โ€œDecoding cellular systems.โ€ All welcome. Register: duke.qualtrics.com/jfe/form/SV_...

02.10.2025 03:06 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Photon-Counting Computed Tomography for Evaluation of Coiled Intracranial Aneurysms BACKGROUND AND PURPOSE: Intracranial aneurysms treated with endovascular embolization often require surveillance imaging using digital subtraction angiography, an invasive, risky, and expensive proced...

๐ŸงชOur new work in AJNR: Photon-counting CT + iMAR offers clear, non-invasive imaging of coiled intracranial aneurysmsโ€”showing promise as an alternative to invasive angiography.

Collab led by Brian Mac Grory with David Urick, Fides Schwartz, David Hasan & Evan Calabrese
๐Ÿ”— www.ajnr.org/content/earl...

23.09.2025 15:32 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Full circle. From my first HLF as a student in 2013 โžก๏ธ to giving a talk on stage as a laureate this year. Grateful for the journey and the community that made it possible. #HLF2025

18.09.2025 21:52 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Yesterday our Center hosted the first Espresso Chat โ˜• with Jeff Hammond! He shared his path from quantum chemistry to #HPC and reminded students to lean into strengths, keep learning, and stay ahead of the curve. Favorite moment: a Valentine that read โ€œJeff the Scientist.โ€ #CareerJourney

12.09.2025 20:35 โ€” ๐Ÿ‘ 11    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Weโ€™re excited to welcome Leah Howell to the Randles Lab as a new graduate student in Biomedical Engineering!

Looking forward to all the discoveries aheadโ€”welcome to the team, Leah!

#RandlesLab #bme #dukebme #dukeuniversity

10.09.2025 16:14 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿงช๐Ÿ‘ฉโ€๐Ÿ”ฌCongrats to Wendy Wu on advancing to PhD Candidacy in Biomedical Engineering! Her work on computational models of cellular mechanics is pushing forward digital health innovation. Proud PI moment (yes, I was the one taking pics mid-exam). #WomenInSTEM #PhDCandidate

08.09.2025 15:08 โ€” ๐Ÿ‘ 9    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Excited to be speaking at the @WichitaState BME Seminar this Friday (Sept 5)!

๐Ÿ“ข Talk: Developing and Applying Vascular Digital Twins
๐Ÿ•‘ 2:00โ€“3:15 PM CT

Exploring HPC + wearables for real-time cardiovascular health. #DigitalTwins #HPC #BME

05.09.2025 02:48 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿงช #CompHealth Corner: High-channel neural interfaces are hereโ€”but routing dense pad grids is a major hurdle. This new paper from #CCDHI member Jonathan Viventi introduces an efficient, automated algorithm to optimize trace paths and layer count in thin-film devices. #Neuroengineering #HCI

29.08.2025 11:47 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Wow, thanks so much for the support and sharing! Iโ€™m really excited about the new initiative.

28.08.2025 19:09 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Launching Fall 2025: Dukeโ€™s Computational & Digital Health Certificate ๐ŸŽ“ Training future leaders at the intersection of AI, modeling, wearables & ethics. Learn more: duke.is/certificate #DigitalHealth #AI @dukeengineering.bsky.social

28.08.2025 13:49 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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New in npj Digital Medicine: Our proof-of-concept digital twins predict pulmonary pressures noninvasively, offering a path to earlier detection & better care for right heart failure. duke.is/hf

27.08.2025 19:34 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Center Names Associate Directorsย  - Center for Computational and Digital Health Innovation The Duke Center for Computational and Digital Health Innovation welcomes our new Associate Directors to its leadership team. The Associate Directors will help expand and strengthen our research and ed...

โ€œGreat teams embrace the fact that the strength of the team is the team.โ€โ€“Coach K
At the Duke Center for Computational and Digital Health Innovation, collaboration drives impact. Weโ€™re excited to welcome our new Associate Directors, who will strengthen our research and education missions.
duke.is/ad

27.08.2025 19:14 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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CompHealth Corner: What Are We Reading?
๐Ÿ“˜ Paper from Center researcher Jonathan Viventi in the Journal of Neural Engineering: a deepest-exit-first algorithm for routing dense pad grids in thin-film neural interfacesโ€”solving a key bottleneck in scaling next-gen implants.
#Neurotech #AI ๐Ÿงช

22.08.2025 21:32 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Fun new wall art from LLNL :) still figuring out where to put it but itโ€™s pretty cool. (And yes those are part of my #SC jacket collection below. We all have SC clothes in our offices right?) #hpc #scivis #artofhpc

21.08.2025 18:27 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿงช When doctors track heart disease, they need scans over timeโ€”but aligning them is tough, tedious, and subjective. We built an algorithm that automates alignment, saving time and effort.

Read more ๐Ÿ‘‰ duke.is/align24

@dukeengineering.bsky.social #research #comphealth #CCDHI #cardiovascular

19.08.2025 13:11 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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CompHealthCorner: HPC powers todayโ€™s AI, science, and innovationโ€”but U.S. leadership is at risk. This Science article urges a bold, whole-nation roadmap to secure the future of high-performance computing. A must-read for anyone in tech policy. #CompHealthCorner #HPC #AI #SciencePolicy

15.08.2025 11:51 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Dr. John Hickey, our co-Associate Director of AI, is pioneering AI-empowered systems biology to advance spatial cell therapies. His award-winning work marries engineering, immunology & computation to shape the future of personalized medicine.
Read more: comphealth.duke.edu/featured-res...

14.08.2025 19:26 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Added some new personal touches to the office to kick off the new year :) as part of my sabbatical this year, we took the kids to Australia (yes I questioned the long flight too :)) and I thought I would add some pics to my office. Do you have family artwork or custom mousepads in your office?

14.08.2025 16:49 โ€” ๐Ÿ‘ 6    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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How can AI in healthcare reduce bias instead of reinforcing it? This weekโ€™s #CompHealthCorner spotlights a new Nursingโ€ฏOutlook article by Benโ€ฏGoldsteinโ€ฏand colleagues on HUMAINEโ€”a teamโ€‘developed curriculum to equip nurse scientists in AI, bias mitigation, and equity.

11.08.2025 13:05 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐ŸงชOopsโ€”Julyโ€™s #CompHealthCorner is a few days late (I was traveling)! Catch up on key papers in ML-driven MD, RAG in medicine, open-source ANS tools, and award-winning cancer simulations. Donโ€™t miss these breakthroughs! ๐Ÿ‘‰ comphealth.duke.edu/comphealth-c... #DigitalHealth #AI #Bioengineering

08.08.2025 20:16 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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