OK

Motivational video for #MigrationMovieMonday. A persistent 4T1 breast cancer cell squeezing itself through a tight constriction despite undergoing repetitive nuclear envelope rupture. Credit: Kristen Nedza @weillinstitute.bsky.social

Once resuspended the pi is 50x. Basically we spin down 150-200 OD of cells and resuspend in 1ml lysis buffer of choice with 1x Pi. The protocol is here: PMID: 24300101. I’d be glad to share a pdf if you don’t have access .

Promega protease inhibitor cocktail G6521 - good luck!

Crude drawing of box with #1-6 indicating tubes

Asking a student over text to send a picture of where I can find the minipreps in her freezer box:

Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.

Model organisms, in particular non-mammalian model organisms, such as yeast, Caenorhabditis elegans, #Drosophila and zebrafish, have long stood at the centre of biological discovery www.nature.com/articles/s41...

Scientists targeted by dark PR tactics: Several academic scientists critical of de-extinction projects have become the targets of anonymous smear articles and weaponized copyright infringement claims:... EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.

My first ever non-peer reviewed science-related piece. Together with Howard Wolinsky and Holger Breithaupt @embopress.org

It's about how scientists critical of de-extinction are targeted by dark PR tactics: www.embopress.org/doi/full/10....

Amazing!!!

Dog sleeping next to firepit

Dog fell over. #happypup #firepit

There’s a glitch in the matrix!

Frog sitting by small pond looking over the water

Freddie was pondering the meaning of flies.

Fearless predators!

Sea Robin fish caught in the NC surf - the animal was caught and released while surf fishing.

It is a bird, it is a fish, no! It is a Sea Robin! #surffishing #catchandrelease

Kids running into the waves as approaching weather turns the sky dark on a late summer beach scene

Here is an end-of-the summer beach picture I took as some weather is rolling in.

Local awkward teens hanging out on our street. #deercam #wildlife

If there is ever a worthier repost!

Great shot!

Scholars sneaking phrases into papers to fool AI reviewers : Using prompt injections to play a Jedi mind trick on LLMs

Hidden prompts in articles to fool #AI reviewers! It'sbrilliant, it's resistance and it's self-defense! It shows the massively wealthy publishing companies that cutting corners is bad for #science! They could use their wealth to pay independent reviewers.... 🧪

www.theregister.com/AMP/2025/07/...

Today in ridiculously priced items from scientific vendors: weighing paper 3x3 in for analytical balances $126 per pack of 500!

Franklin W. Stahl, 95, Dies; Helped Create a ‘Beautiful’ DNA Experiment

Franklin W. Stahl, 95, Dies; Helped Create a ‘Beautiful’ DNA Experiment www.nytimes.com/2025/07/07/s...?

E-sports nonsense even on my bananas!

I do not like AI in Slack
I do not like AI on Mac
I do not like AI in Zoom
I don’t want AI in my room
I do not want ChatGPT —
please stop, AI, and leave me be!
I don’t want AI here, or there;
I don’t want AI anywhere!

(… okay, okay — had to Seuss it, sorry 😇)

Nature reclaiming this excavator along the Chickahominy river, VA.

#BethesdaDeclaration @standupforscience.bsky.social

I decided to share the opportunity to sign the support letter for the Bethesda Declaration with my entire email list for our family holiday letter.

I learned some important lessons.

1/n

Microtubules do more than move chromosomes—they help clean up cellular messes too. 🧹 Eric Rubenstein of Ball State University shows Kar3 and Vik1 are key to protein quality control via ER-associated degradation.
📖 www.molbiolcell.org/doi/10.1091/... #ASCB #CellBiology #ERAD #Proteostasis

NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.

An analysis shows that NIH grant awards supported 407,782 jobs and $94.58 bn in new economic activity nationwide, the largest figure in the history of the report, w/ an ROI of $2.56 for every $1 in awards.

Deep cuts to NIH funding will contribute to a recession.
www.forbes.com/sites/michae... 🧪🔬

www.standupforscience.net/bethesda-dec...

How a discovery in Yellowstone National Park led to the development of PCR - Richmond Scientific A discovery in Yellowstone National Park led to the development of PCR, the gold-standard COVID-19 tests used to fight the global pandemic.

Reminder: Nobel-prize winning PCR (1983), used in basically all genetic tech today, was only possible because of extremophile bacterium discovered in 1964 in Yellowstone funded by a small ~$80k NSF grant with no obvious application at the time. #science 🧪
www.richmondscientific.com/how-a-discov...

Wow - no more OneDrive saves! Thank you! Made my day! Worked like a charm!

Lucy #dog is showing off her prized possession - a paper towel role! Surprisingly not yet shredded!

Assassin #bug in the yard