Jie Xiao

Research Technologist (Biophysics & Biological Chemistry) | Johns Hopkins University 119351 jobs in Johns Hopkins University

Research technologist position available in the Xiao lab: We are looking for a talented recent college graduate interested in learning how a single-molecule imaging lab operates to join our team. Check it out here: hiring.jhu.edu/careers?quer...

Differential effect of supercoiling on bacterial transcription in topological domains Author summary We are interested in understanding how bacteria regulate the expression of their genes independent of protein-based transcription factors. One mechanism is through DNA mechanics caused ...

doi.org/10.1371/jour...

Chromosomal Topological Domain Formation Modulates Transcription and the Coupling of Neighboring Genes in Escherichia coli Chromosomal topology and transcription are tightly coupled, yet the quantitative impact of topological constraints on transcription, supercoiling, and the potential coupling between neighboring genes ...

‘Chromosomal Topological Domain Formation Modulates Transcription and the Coupling of Neighboring Genes in Escherichia coli‘ by Drs. Nico Yehya, Christopher Bohrer, and collaborators, is now available on bioRxiv. Check it out! doi: doi.org/10.1101/2025...

I'm very proud of Boaz Goldberg, my undergraduate student, who just published a first-authored paper on ‘Differential effect of supercoiling on bacterial transcription in topological domains‘ in PLoS Computational Biology. DOI: 10.1371/journal.pcbi.1012764

Abstract submission deadline is June 30, 2025!

Join us at the BPS Thematic Meeting on Spatial Organizations of Biological Functions in beautiful Bangalore, India! The early registration deadline is July 21st, 2025. www.biophysics.org/meetings-eve...

FtsN Coordinates Septal Peptidoglycan Synthesis, Degradation In the intricate world of bacterial cell division, coordination of cell wall remodeling is paramount for survival and proliferation. A recent groundbreaking study has unveiled a previously

And here is the accompanying commentary. The summary is pretty good (AI or real person?), but the AI-generated image is off. We are bacterial cells!

scienmag.com/ftsn-coordin...

Third track model for coordination of septal peptidoglycan synthesis and degradation by FtsN in Escherichia coli - Nature Microbiology Partitioning of FtsN and the septal peptidoglycan synthesis complex between an active synthesis track and an inactive denuded glycan track coordinates opposing peptidoglycan synthesis and degradation ...

Our new paper on FtsN is out! Now there are three tracks for organized cell wall constriction-- the old, boring E. coli always manages to surprise us.

A special shout-out to all the people who made this work possible, especially Dr. Jason Lyu, and Dr. David Weiss.

www.nature.com/articles/s41...

Join us! Women in Biophysics: journeys and challenges

Monday, March 24th, 12:00 pm to 1:30 pm EST

Registration link: us02web.zoom.us/meeting/regi...

Four prominent women biophysicists will share their experiences in life and career. Join us for this unique opportunity featuring live interviews!