UCI Center for the Study of Cannabis

📣 Cannabis researchers!

UCI ICAL Tissue Bank: adolescent Δ9-THC–exposed rodent brain + peripheral tissue.

FREE (accredited institutions) | No DEA license
Shipping covered by requester

Limited supply. DM for details.

#CannabisResearch #THC

🎙️ Science at the Source (Ep. 8)

Olufunke Ajeigbe, PhD (UC Irvine) on translational science, global training & academic pathways.

🎧 Watch: /@ucicenterforthestudyofcann5100
#ScienceAtTheSource #UCIrvine

🌿🧠 Can cannabis help manage chronic pain?
Dr. Daniele Piomelli explains how THC works through cannabinoid receptors—and what the science actually says.

📺 Watch: www.youtube.com/watch?v=A7T1...

#CannabisResearch #ChronicPain #THC #EndocannabinoidSystem #Neuroscience

🌿 Is cannabis a psychedelic?
Dr. Daniele Piomelli breaks it down in a crisp 20-min talk—what counts as a psychedelic, how cannabinoids compare, and why it matters for mental health & neuroscience.

🎥 Watch: youtu.be/G0tagjX8COw

#CannabisScience #Neuroscience #Psychedelics #EndocannabinoidSystem

New resource for cannabis & cannabinoid researchers!
The Resource Center for Cannabis & Cannabinoid Research (R3CR) is a new hub helping scientists navigate regulations, access high-quality materials, and build strong proposals.

Led by experts from UM, USP & WSU.
More: r3cr.org | LinkedIn @R3CR

📢 Cannabis & cannabinoid researchers:
The UCI ICAL Tissue Bank offers FREE adolescent Δ9-THC tissue (brain + peripheral organs) from male & female rodents. Flash-frozen or fixed. No DEA license needed. Brain tissue limited—first come!
📩 Contact us
@ucicannabis

From ICAL — excited to share two 2025 publications on adolescent THC exposure and its effects on the brain and body:

📄 J Vis Exp — THC in adolescent & adult mice (Jung KM et al.)
📄 Toxicol Sci — Adolescent THC impairs testicular function (Lim J et al., Jung KM)

Congrats to all involved! 🧠✨
#UCI

Big congrats to Steve Mahler’s group at UCI ICAL! 🎉

Their team published 3 major papers in 2025 — including one featured on the cover of the Journal of Neuroimmunology — advancing research on cannabinoids, addiction, and brain–immune interactions. Proud of this amazing work! 🧠✨

🎆 Happy New Year!
Wishing you a bright, bold, and brilliant 2026 from all of us at UC Irvine’s ICAL! ✨
Excited to see what new discoveries in cannabis science await us!

🎉 Happy Holidays!
From all of us at UC Irvine's ICAL, wishing you joy, rest, and a bright start to 2026! ✨

🚨 Must-watch: Dr. Steve Mahler on how cannabinoids shape motivation, reward, and craving—and why it matters for addiction science.

🎥 www.youtube.com/watch?v=9ImB...

@uci_cannabis

#Neuroscience #AddictionResearch #Endocannabinoids

📢 Researchers: UCI ICAL Tissue Bank has adolescent Δ9-THC mouse/rat brain & organ samples! 🧠👩🔬❄️ FREE for accredited labs, no DEA license needed. First-come, first-served!

📸 IG: @uci_cannabis | 🔗 X: @ucicannabis

#CannabisResearch #THCResearch #Neuroscience

Coming back to this fantastic conversation with ICAL Director Dr. Daniele Piomelli — from the endocannabinoid system to where cannabis science is headed next. A great intro to the science behind cannabinoids.
🎥 www.youtube.com/watch?v=Px45...

🚨 Re-upping a fan favorite:
Dr. Hilary Marusak + Dr. Christine M. Gall on cannabis, memory, adolescent development, and sex differences in the brain.

🎥 Watch here: www.youtube.com/watch?v=iBdV...

Follow: @uci_cannabis

#ScienceAtTheSource #Neuroscience #THC #Memory #AdolescentBrain

🔁 Resharing this powerful episode!
Dr. Hilary Marusak talks with Dr. Rodrigo Klein (UC Irvine) about how THC shapes the developing brain—from fetal stages to adolescence.

👉 Watch: www.youtube.com/watch?v=oap6...

🚨 Microglia & addiction? In Science at the Source Ep. 6, Dr. Hilary Marusak chats with Maricela Martinez on how the brain’s immune cells shape adolescent circuits—and what THC, nicotine, & opioids do. 🧠🌿💡

Watch: www.youtube.com/watch?v=koYL...
#Neuroimmunology #Addiction #AdolescentBrain #Microglia

🚨 Researchers: Need adolescent THC tissue?

The UCI ICAL Tissue Bank offers brain & organs from THC-treated rodents—flash-frozen or perfused. FREE for accredited labs. No DEA license needed. First-come, first-served!

📩 DM for availability & protocols 🌱🔬

#CannabisResearch #THC #TissueBank #Science

New ICAL paper in J. Neurosci!
Microglia support endocannabinoid-dependent LTP and episodic memory.

Microglia depletion disrupted LTP and memory in mice—effects reversed by enhancing 2-AG signaling.

📄 Chavez et al., 2025
🔗 www.jneurosci.org/content/45/2...

New commentary from ICAL Director Dr. Daniele Piomelli in JPET: “Liking isn’t enough: You got to want it.”
As cannabis moves toward Schedule III, Piomelli explores the neurobiology of motivation, abuse liability, and what drives use beyond enjoyment.
🔗 jpet.aspetjournals.org/article/S002...

ICAL Tissue Bank - UCI Center for the Study of Cannabis ICAL Tissue Bank ICAL maintains a biobank of brain and peripheral organs collected from mice and rats treated in adolescence with D9-tetrahydrocannabinol (THC) or vehicle. Both male and female…

🧠 THC researchers: Get free adolescent THC brain & organ tissue from UCI ICAL Tissue Bank! No DEA license needed, shipping covered. Limited supply—first-come, first-served! 🌱🔬
📩 DM for info
IG: @uci_cannabis | X: @ucicannabis

REQUEST HERE: cannabis.uci.edu/ical/tissueb...

#CannabisResearch #THC

In case you missed it from ICAL: New publication! Protocol for administering Δ9-THC in adolescent & adult mice, showing effects on catalepsy, locomotion, and pain — with safe, legal handling tips. 🔬💊

Link here: app.jove.com/t/68358/admi...

🎙️ New Science at the Source!

Dr. Hilary Marusak + Rodrigo M. Klein, PhD (UC Irvine) on how THC impacts the developing brain.

🧠 Resilience & risk
👩🔬 Microglia & endocannabinoid system
🌍 Context & cannabis use

👉 Watch: www.youtube.com/watch?v=oap6...

📢 Cannabis researchers: UCI ICAL Tissue Bank 🧠🫀
Brain & organs from THC/vehicle-treated mice/rats, prepped for molecular studies. FREE, shipping included, no DEA needed. ⚠️ First-come, first-served!
cannabis.uci.edu/ical/tissueb...

🚨 New Science at the Source!

Dr. Hilary Marusak talks with Dr. Christine Gall (UC Irvine) on how adolescent THC impacts memory, sex differences, and brain health.

🎥 youtu.be/iBdVUbXZNOA

#THC #AdolescentBrain #Memory #ScienceAtTheSource

Welcome to another enlightening episode of Science at the Source! In this episode, Dr. Hilary Marusak engages with Dr. Kwang-Mook Jung, a pioneering researcher exploring the intersection of… THC Exposure and Metabolic Health with Dr. Kwang-Mook Jung | Science at the Source Ep. 3

🚨 Still thinking about this convo with Maricela Martinez.

What if the key to understanding addiction risk lies in the brain’s immune cells?
Episode 6 of Science at the Source dives into microglia, adolescence, and how early drug exposure may prime the brain.

🎥 youtu.be/RO_g9KTaMCA

#Microglia #THC

🚨 Save the Date! 🚨
The MACRC 2025 Conference — the first official ICRS Chapter meeting 🍃
📅 Nov 14–16, 2025 | 📍 Kitty Hawk, NC
Abstracts & registration open (early bird thru Sept 21)!
👉 www.m-acrc.org

#CannabinoidResearch #MACRC2025 #ICRS

Welcome back to Science at the Source! 🎙️ In this episode, we sit down with Dr. Steve Mahler, neuroscientist and Professor at UC Irvine, to explore how the brain’s motivation and reward systems are… Exploring Motivation, Cannabinoids, and the Brain with Dr. Steve Mahler| Science at the Source Ep. 5

🚨 Rewind to Science at the Source Ep. 5
Dr. Steve Mahler breaks down the neuroscience of craving, THC, and motivation—and what it means for cannabis use and addiction treatment. Still thinking about this one.
🎥 www.youtube.com/watch?v=9ImB...
IG → @uci_cannabis #CannabisResearch #MotivationAndReward

ICAL Tissue Bank - UCI Center for the Study of Cannabis ICAL Tissue Bank ICAL maintains a biobank of brain and peripheral organs collected from mice and rats treated in adolescence with D9-tetrahydrocannabinol (THC) or vehicle. Both male and female…

🚨 Cannabis researchers: Need THC-exposed brain or organ samples? 🧠🫀

The UCI ICAL Tissue Bank offers FREE tissues (U.S. & abroad), no DEA license needed.
Brain tissue = high demand—act fast! 📩

🔗 cannabis.uci.edu/ical/tissueb...

@uci_cannabis #CannabisResearch #THCResearch

🧪 New ICAL protocol paper: Standardized methods for administering THC to adolescent & adult mice.

Includes prep, legal compliance, and key readouts: catalepsy, locomotion, nociception.
🔗 app.jove.com/t/68358

🧠 Essential for modeling developmental effects of cannabis.
#THC #CannabisResearch #ICAL

🚨 Vaping THC ≠ smoking it.

In Science at the Source Ep. 4, Dr. Alexa Torrens breaks down how vaping affects the teen brain—& why the nose matters more than you think.

Watch: www.youtube.com/watch?v=D9hc...
Follow → @uci_cannabis

#CannabisResearch #THCVaping #AdolescentBrain #ScienceAtTheSource