Andrew Routh andrewrouth - Bluesky Statics

SARS-CoV-2 EndoU-ribonuclease regulates RNA recombination and impacts viral fitness - Nature Communications Known to augment host innate immunity, Zhou and Ahearn et al. shows that a SARS-CoV2 NSP15 mutant also increases viral recombination and reduces sub-genomic message. Results articulate a novel role fo...

New paper from our lab on CoV recombination in @natcomms.nature.com: www.nature.com/articles/s41...

Collaboration w/ @andrewrouth.bsky.social, the work led by @tommygottago.bsky.social & Yani provides insights into #SARS2 recombination & immune induction.

Some takeaways for the TLDR crowd (1/13)

10.12.2025 15:08 — 👍 10 🔁 4 💬 1 📌 0

We are witnessing the destruction of science in America | Paul Darren Bieniasz If we stay on this administration’s course, future life-saving medicines may never be invented

I could literally quote every single sentence of this commentary, so I'm not going to - just read the whole thing.

And thanks, Dr. Bieniasz, for saying it as it is and showing true leadership. We need that from more scientists and scientific leaders.

www.theguardian.com/commentisfre...

10.04.2025 00:35 — 👍 194 🔁 78 💬 3 📌 4

If someone—or something—is infected with both #birdflu (H5N1) and seasonal flu (H1N1), the viruses can swap genes through reassortment. Scientists are watching closely, as this genetic shuffle could create a new strain with unpredictable traits—like easier human transmission. More: ow.ly/aoeA50VxSwG

09.04.2025 23:52 — 👍 19 🔁 5 💬 2 📌 0

Can we use social evolution to fight pathogens? @asgriffin.bsky.social and I review the evidence for 'cheat therapy' in bacteria and viruses...

🧪🦠 #socialviruses #evosky #virosky

1/3

28.03.2025 18:03 — 👍 47 🔁 16 💬 1 📌 0

How does enterovirus protease specifically recognize its viral RNA genome?

Hint: It takes two!

Our first post on bluesky - Happy to share our new publication.

Structure of coxsackievirus cloverleaf RNA and 3C protease dimer establishes its RNA-binding mechanism
www.science.org/doi/10.1126/...

13.03.2025 01:17 — 👍 13 🔁 4 💬 1 📌 1

🙋

10.11.2024 19:39 — 👍 1 🔁 0 💬 1 📌 0

Posts by Andrew Routh (@andrewrouth.bsky.social)