Jamil Kanji, MD

Mississippi experiences explosive growth in maternal syphilis

Maternal and congenital syphilis are markers of under development and lack of public health infrastructure.
Sad that we are adding " explosive growth in maternal syphilis" to the list of public health failures closing out 2025.
www.cidrap.umn.edu/sexually-tra...

The #Ebola outbreak in central DRC that was first reported in September has been declared over. The outbreak, the country's 16th (I think), involved 64 cases (53 confirmed, 11 probable), of which 45 were fatal. It occurred in Bulape health zone in Kasai province. www.who.int/emergencies/...

Continuation versus temporary interruption of immunomodulatory agents during infections in patients with inflammatory rheumatic diseases: a randomized controlled trial Immunomodulatory agents (IA) are commonly used to treat inflammatory rheumatic diseases (IRDs). Guidelines typically recommend temporary...

Continuation versus temporary interruption of immunomodulatory agents during infections in patients with inflammatory rheumatic diseases: a randomized controlled trial

✅ Just Accepted
⭐ Editor's Choice
#IDSky

2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19 These recommendations include pre-exposure prophylaxis for immunocompromised persons and treatment of severe or critical COVID-19.

2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19

✅ Just Accepted
#IDSky

First Case of Neuroinvasive Oropouche Virus in Wisconsin: A Case Report Oropouche virus (OROV) is a re-emerging arbovirus that poses a yet undetermined degree of threat to the United States (US), with outbreaks reported in the Caribbean and South America, including new areas of spread, since the end of 2023.

First Case of Neuroinvasive Oropouche Virus in Wisconsin: A Case Report

✅ Just Accepted
#IDSky

Measles 'out of control,' experts warn, as Alberta case counts surpass 1,000 | CBC News Alberta's measles outbreaks have now eclipsed the 1,000 case milestone and infectious diseases specialists are warning the virus is likely "impossible to contain," given the current level of transmiss...

Measles out of control in Alberta 🇨🇦

www.cbc.ca/news/canada/...

Level of antibody to hepatitis B surface antigen declined below 10 mIU/ml is still protective - npj Vaccines npj Vaccines - Level of antibody to hepatitis B surface antigen declined below 10 mIU/ml is still protective

"Level of antibody to hepatitis B surface antigen declined below 10 mIU/ml is still protective".
New study in NPJ Vaccines @natureportfolio.nature.com
Interesting prospective study among infants exposed to HBV positive mothers
#IDSky

www.nature.com/articles/s41...

COVID-19 vaccination not only helps a pregnant mother, but also protects the baby when they don't have their own immune response, says John B. Lynch, MD, FIDSA.

Our full media briefing on the impact of the changes in HHS COVID-19 vaccine recommendations: www.idsociety.org/multimedia/v...

👏🏽👏🏽👏🏽🇨🇦🇨🇦🇨🇦

Candida vulturna, the Next Fungal Menace? A Narrative Review Introduction The yeast Candida vulturna is a member of the Candida haemulonii species complex, like its close relative Candida auris. Members of this species complex, including C. vulturna, often di...

Candida vulturna (member of Candida haemulonii species complex)can be misidentified with reduced azole and ampho susceptibilities. #MedMyco #IDSky

Outcome predictors of Candida prosthetic joint infections: a systematic review and meta-analysis Candida prosthetic joint infections (CPJI) are serious complications, for which optimal surgical management and antifungal therapy remain unclear.

Outcome predictors of Candida prosthetic joint infections: a systematic review and meta-analysis

✅ Just Accepted
⭐ Editor's Choice
#IDSky

Evidence for selection of doxycycline resistance in Staphylococcus aureus in DoxyPrEP study In their doxycycline preexposure prophylaxis (doxyPrEP) randomized controlled study, Grennan et al. conclude that the risk of doxyPrEP selecting for antimicrobial resistance is low.

Evidence for selection of doxycycline resistance in Staphylococcus aureus in DoxyPrEP study

✅ Just Accepted
#IDSky

Every 10 seconds vaccination saves a life. Immunization for all is Humanly Possible

It’s #WorldImmunizationWeek

Vaccines have saved 154 million lives in the last 50 years. That’s 6 lives every minute.

A reminder of what is #HumanlyPossible. Science saves lives.

#VaccinesWork
bit.ly/wiw2025

Tecovirimat is an effective treatment for mpox The antiviral drug tecovirimat is frequently used to treat mpox. But is it really effective, especially against the new, more pathogenic strain of the virus that has been in circulation since 2024? A ...

🦠 New study by Institut Pasteur confirms tecovirimat remains effective against all mpox strains, including the new, more pathogenic clade 1b. No resistance mutations detected so far.

Essential to improve outbreak response and treatment strategies.

Read more 🔗 www.pasteur.fr/en/research-...

Wonderful to see these excellent results from a large, multi-country evaluation of tongue swabs for TB diagnosis!

Diagnostic accuracy of swab-based molecular tests for tuberculosis using novel near point-of-care platforms: A multi-country evaluation

www.medrxiv.org/content/10.1...

Clinical features and outcomes of Human Herpesvirus-6 DNAemia in critically ill patients: a retrospective multicenter analysis Human Herpesvirus-6 (HHV-6) DNAemia is not rare in intensive care unit (ICU) patients. However, evidence for a causal association of HHV-6 DNAemia with organ disease and with mortality is limited in this setting.

Clinical features and outcomes of Human Herpesvirus-6 DNAemia in critically ill patients: a retrospective multicenter analysis

✅ Just Accepted
#IDSky

Measles: the urgent need for global immunisation and preparedness Since the beginning of 2025, the USA has reported a rise in the number of measles cases, with 607 confirmed infections across multiple states, as of April 3, 2025.1 Notably, 97% of these cases are amo...

🚨 With > 600 confirmed measles cases in 2025, the U.S. risks losing elimination status- despite vaccines costing <$1/child.

In our new commentary in @thelancet.bsky.social @saadomer.bsky.social and I call for urgent action on global immunization & preparedness
www.thelancet.com/journals/lan...

Texas records second measles-related death, local media report A second child with measles has died in Texas where hundreds of cases of the disease have been recorded in recent weeks, prompting U.S. Health Secretary Robert F. Kennedy Jr. to plan a trip to the state, local media reported early on Sunday.

Another life lost to measles in Texas — the second in the state, third in the U.S. this year.

A measles vaccine costs less than $1.
Such a small price to pay to prevent a tragedy.

#VaccinesSaveLives #Measles #PublicHealth

www.google.com/url?q=https:...

RFK, Jr. Laying Off Entire Office Of Infectious Disease And HIV/AIDS Policy Robert F. Kennedy, Jr., the Secretary of Health and Human Services is reportedly laying off the entire Office Of Infectious Disease And HIV/AIDS Policy. Here's the impact

Because, why not? 🤦🏾‍♀️
www.forbes.com/sites/brucel...

Nawruz Mubarak! 😊😊😊

Good results for PJI caused by Corynebacterium spp. after algorithmic surgical approach and rifampicin combination in implant retention he aim of this study was to evaluate success rate of a clinical cohort of patients with PJI, where Corynebacterium spp. was the causative organism (CPJI), treated according to an algorithm. Methods: From the institutional bone infection registry 44 patients treated for CPJI between 2007 to 2023 were identified.

Good results for PJI caused by Corynebacterium spp. after algorithmic surgical approach and rifampicin combination in implant retention

✅ Just Accepted
⭐ Editor's Choice
#IDSky

Is this an opportunity for the rest of the world to step up and create a situation not so US dependent? WHO needs to get aggressive with other countries and ask for more input. Easier said than done. I know.

Second death reported in growing measles outbreak The death of a New Mexico adult comes eight days after a 6-year-old child succumbed to the disease in Texas last week.

Second measles death in the US

In a country that eliminated measles in 2000 due to the success of vaccination efforts

www.washingtonpost.com/health/2025/...

Adult infected with measles dies in New Mexico, health officials say Person from Lea county had been unvaccinated and did not seek care but virus not yet confirmed as cause of death

Childhood illnesses tend to be quite more severe in adults. Every adult I have ever seen with measles or chickenpox or mumps was hospitalized or very ill. To die of measles in 2025 is a sad and deeply unfortunate choice.
www.theguardian.com/us-news/2025...

Dr @hildabast.bsky.social had warned us about PubMed and suggested alternatives

Formerly anti-vax parents on how they changed their minds: ‘I really made a mistake’ Researchers believe personal stories are more persuasive than facts alone in addressing vaccine skepticism

This is an important read. Most vaccine skeptic parents think they are protecting their children by choosing not to vaccinate. This is thanks to pervasive mis/disinformation. Understanding why the change their minds is informative to improve vaccine uptake.
www.theguardian.com/global/2025/...

CDC Staff Prohibited From Co-Authoring Papers With World Health Organization Personnel It’s just the latest “Orwellian” crackdown on government scientists.

FFS!

CDC Staff Prohibited From Co-Authoring Papers With World Health Organization Personnel

www.huffpost.com/entry/cdc-wh...

San Antonio-area charter school now says they have a case of rubella, not measles Officials at Legacy Traditional School – Cibolo said Thursday they had confirmed a measles case in a first-grade classroom. They later said the case was actually rubella.

Not too suprising that when the uptake of the MMR vaccine is low, it brings not 1 but all 3 dieases it usually protects from:
measles
Mumps and as here
Rubella

www.tpr.org/education/20...

With CDC and Public Health decisions/meetings in the USA being postponed, now is the time for PHAC in Canada to step up! PHAC should become a beacon for Public Health leadership!

10/ The solution is simple: Vaccination.

📌 The MMR vaccine is safe, effective, and necessary.
📌 To maintain elimination, we need ≥95% coverage.
📌 Public health vigilance is key.

Measles elimination was a major victory—let’s not lose it.
Outbreak are NOT USUAL NOT SHOULD THEY BECOME THE NORM.