Sander Smits

@spp2330.bsky.social

Thanks for highlighting our work done at @hhu.de @chemiehhu.bsky.social published in @angewandtechemie.bsky.social , Aubrey @aubreyzerkle.bsky.social! Rare earth elements rock! doi.org/10.1002/anie...

AP4A functions as a regulatory switch of protein acetylation, connecting stress signaling to central metabolism.

@synmikro.bsky.social @unimarburg.bsky.social @mpimicrobiomarburg.bsky.social

Enjoy the reading:

www.nature.com/articles/s41...

Lasse presents our CRC1535 MibiNet project at the first RNA confluence meeting at the EMBL.
@rhinelandrna.bsky.social @mibinet.bsky.social

‪
Please RT:
Looking forward to our International Symposium on "Microbial Networking - from organelles to cross-kingdom communities".
Highlight of our first funding period of our Collaborative Researc Center @mibinet.bsky.social, @dfg.de

www.sfb1535.hhu.de/mibinet

@hhu.de , @fz-juelich.de

Super happy to share that our Chemical Science article ‘Structural control of dynamic covalent cages: kinetic vs. thermodynamic assembly and PFAS removal from water’ (pubs.rsc.org/doi/D5SC02247A) has been selected for the 2025 most popular supramolecular articles collection 🎉

Happy to announce that our review article on vesicle-coupled mRNA trafficking is now availalbe

@mibinet.bsky.social

#EMBOrnaLocalization

link.springer.com/article/10.1...

@mibinet.bsky.social

Strukturanalyse: Veröffentlichung in ACS Sensors Um Stoffwechselprozesse zu verstehen, ist es wichtig, einzelne wichtige Elemente in lebenden Organismen nachweisen zu können. Forschenden der Heinrich-Heine-Universität Düsseldorf (HHU) entwickelten n...

I feel very grateful that our recent publication on rapid biosensor creation has been announced by HHU (Heinrich Heine University Düsseldorf). 🍀🙏🏼🤩🧪🦠🧫🔬

www.hhu.de/news-einzela...

A Novel Biosensor for Ferrous Iron Developed via CoBiSe: A Computational Method for Rapid Biosensor Design Genetically encoded biosensors enable the monitoring of metabolite dynamics in living organisms. We present CoBiSe, a computational biosensor design approach using Constraint Network Analysis to ident...

✨ I am thrilled to share ✨ that our paper on computational biosensor design has just been published!

Huge thanks to all co-authors and collaborators for the great teamwork and dedication throughout this journey! 🙌

📄 Read the paper here:
pubs.acs.org/doi/10.1021/...

We Are very happy that our Paper was published. Thank to everyone involved

pubs.acs.org/doi/10.1021/...

@mibinet.bsky.social @mfeldbruegge.bsky.social @frunzkelab.bsky.social

🔬 Job Alert! 🚨

Goethe University Frankfurt is hiring a Head of our new Imaging Facility at Campus Riedberg!

Lead and support a vibrant imaging community, working with cutting-edge microscopes, e.g. a new Zeiss LSM 980, a Z1 Light Sheet, and a new Leica Stellaris.

gerbi-gmb.de/resources/ca...

Abteilungsleitung (m/w/d) Forschungsmanagement und Transfer - Heinrich-Heine-Universität Düsseldorf Heinrich-Heine-Universität Düsseldorf bietet Stelle als Abteilungsleitung (m/w/d) Forschungsmanagement und Transfer in Düsseldorf - jetzt bewerben!

Werde Teil des Teams @hhu.de:
#Stellenangebot, scheinbar unbefristet. Grüße an #ichbinHanna & #ichbinReyhan

@mfeldbruegge.bsky.social @mibinet.bsky.social

Vesicle-coupled mRNA transport and translation govern intracellular organelle networking - EMBO Reports Eukaryotic cells are highly compartmentalized, enabling sophisticated division of labour. For example, genetic information is stored in the nucleus while energy is produced in mitochondria. Despite th...

Very happy to See This Published!!!! Thanks for the collaboration

link.springer.com/article/10.1...

Vesicle-coupled mRNA transport and translation govern intracellular organelle networking - EMBO Reports Eukaryotic cells are highly compartmentalized, enabling sophisticated division of labour. For example, genetic information is stored in the nucleus while energy is produced in mitochondria. Despite th...

Very happy to See This Published!!!! Thanks for the collaboration

link.springer.com/article/10.1...

Finally out – It is all about cholesterol
Thanks to all for this excellent collaboration

Postdoc (m/f/d) in Endosymbiosis Research

📢Postdoc position available!🧪🧫🧬
Our group is seeking a motivated researcher to investigate the molecular mechanisms driving host–endosymbiont interactions.
Full details & application: karriere.hhu.de//index.php?a....
Please help us get the word out!

DFG fördert Projekte für ressourceneffizientere Großgerätenutzung in der Forschung

Die DFG fördert Projekte für ressourceneffizientere Großgerätenutzung in der Forschung mit insgesamt ca. 5,5 Mio €. Außerdem werden zusammen mit der GWK bis Ende 2025 Anträge unter dem üblichen Schwellenwert möglich, die eine längere Nutzung vorhandener Geräte erlauben.
Details: sohub.io/r4km

crTP X-ray structure

✨X-ray crystallography reveals surprising twist in how proteins enter the unique photosynthetic organelles of Paulinella. The chromatophore targeting peptide (crTP) folds into a 3D structure, hinting that folded proteins cross peptidoglycan and inner membrane. (1/2)
academic.oup.com/plphys/artic...

New publication in J Mol Biol
New insights in to the function of the CLD and the entire hemolysin secretion machinery. Thanks to Holger Gohlke’s lab and CSS for the wonderful collaboration. Congrats to Sakshi and Cigdem!

Hijacking a bacterial ABC transporter for genetic code expansion - Nature Bacterial ATP-binding cassette (ABC) transporters can be utilized and engineered to transport non-canonical amino acids into Escherichia coli for highly efficient synthesis of proteins with novel func...

🚨Our paper is out! 🥳
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...

it all started years ago with a failed experiment
🧵👇 1/9

Please RT:
We have an opening for a junior group leader position in „Phage Biology & Biotechnology“.
www.fz-juelich.de/de/karriere/...

Interested candidates are encouraged to contact me via email for further details.

@spp2330.bsky.social; @mibinet.bsky.social

Excited to share our latest work, spearheaded by @gabmrojas.bsky.social!

GPCRs are central sensors in eukaryotes, but little is known about them in fungi. In Ustilago maydis, we now uncovered a host-dependent GPCR mechanism that promotes fungal infection.

Gabriel nicely explains the full story👇

Evolutionary refinement of mitochondrial and plastid targeting sequences coincides with the late diversification of land plants Abstract. Plastids and mitochondria are key to plant survival and adaptation. The evolutionary progress of land plants (embryophytes) witnessed gene and ge

The evolution of land plants involved a charge-based adaption in the targeting sequences for #mitochondria and #chloroplasts and the origin of their de/phosphorylation.

#science 🧪

academic.oup.com/mbe/advance-...

✨ Lust auf ein Studium mit bunten Farben, spannenden Apparaturen und mikroskopisch kleinen Stoffen? ✨👩🏼‍🔬👨‍🔬
🧪 Chemie oder Wirtschaftschemie könnten da genau das richtige für dich sein!
💡 Neu: Wirtschaftschemie ist ab sofort zulassungsfrei.

Glutathione S-Transferase Mediated Epoxide Conversion: Functional and Structural Properties of an Enantioselective Catalyst Styrene is a naturally occurring but mainly anthropogenically produced aromatic compound. It is degraded via different routes in nature but often activated to styrene oxide, predominantly to its (S)-e...

Just moved online:

Glutathione S-Transferase Mediated Epoxide Conversion: Functional and Structural Properties of an Enantioselective Catalyst | ACS Catalysis pubs.acs.org/doi/10.1021/...

I am honored and excited that our research on #nitrogenases and the conversion of #CO2 to hydrocarbons is highlighted in the Yearbook 2024 of the Max Planck Society, see page 29. An English and a German version of the Yearbook are available in www.mpg.de/13631298/yea....

Studierende schreiben über Prof. Dr. Michael Schmitt: „Er zeichnet sich durch eine ausgezeichnete Verbindung von fachlicher Inhaltvermittlung, menschlicher Nähe und dem gezielten Fördern des Lernprozesses aus.“

Fachliche Exzellenz und menschliche Nähe: diese Kombination beschreibt unseren heutigen #hhuLehrpreis2025-Nominierten Prof. Dr. Michael Schmitt @lasermichel.bsky.social aus der Chemie @hhu.de perfekt. In seinen Vorlesungen gibt er viel Raum für Diskussion. 🎓💬

T7 RNA polymerase-based gene expression from a transcriptionally silent rDNA spacer in the endosymbiont-harboring trypanosomatid Angomonas deanei Eukaryotic life has been shaped fundamentally by the integration of bacterial endosymbionts. The trypanosomatid Angomonas deanei that contains a β-proteobacterial endosymbiont, represents an emerging ...

Excited to share that our T7 RNA polymerase-based expression system brings a new level of versatility to Angomonas deanei as a model for studying endosymbiosis!
doi.org/10.1371/jour...