August is Make a Will Month — the perfect time to protect what matters most and plan for the future. This year, consider including MPN Research Foundation in your will, trust, or estate plan. 

Link to: Planning Toolkit | https://plannedgiving.mpnresearchfoundation.org/planning-toolkit

The August edition of ‘“Under the Microscope’” hit your inboxes at 5PM CT today!  
Join our community today to receive these stories and so much more with this link: https://mpnresearchfoundation.org/subscribe-to-our-newsletter/

Thousands of employers match charitable donations made by their employees, but most people never take advantage of it.  It only takes a minute to see if your employer matches - check today: 
https://mpnresearchfoundation.org/donate-to-mpn-research/  

#EmployerMatch #DoubleYourDonation #MPNResearch

🧬 Essential thrombocythemia (ET) isn’t one-size-fits-all. 

Genetic mutations like JAK2, CALR & MPL impact platelet levels, clot risk & treatment. Genetic testing = better care decisions.  

Know your mutation, know your path. 

#MPNAwareness #GeneticTesting #ET

🏆 Big moment for MPNs: PV research took the plenary stage at #ASCO2025. Dr. Andrew Kuykendall presented VERIFY trial results on rusfertide: 

✓ 62% maintained Hct <45% 
✓ Better symptom control 
✓ Fewer skin malignancies 

#MPNs #PVawareness #Rusfertide #VERIFYtrial

Patients and caregivers play a critical role in shaping the future of MPN research. Join us for an empowering session exploring how your voice can influence every stage of research & drug development. 

Register now: https://us02web.zoom.us/webinar/register/WN_RqcXr7lLQZ-MVvpRae4SeA#/registration

Dr. Gabriela Hobbs, MD repurposes clinical trials that better serve patients. Learn how she’s turning every tissue sample into progress.

Read more: https://mpnresearchfoundation.org/news/every-sample-every-step-how-dr-gabriela-hobbs-is-rethinking-the-transplant-journey-in-mpns/

#MPNs @MPNResearch

The Leukemia & Lymphoma Society (LLS) & MPN Research Foundation unite to provide clinical trial nurse navigation support. 

Get support today: https://mpnresearchfoundation.org/mpn-clinical-trials/

#MPNs #ClinicalTrials #Hematology #Oncology #PatientSupport #MPNRF #LLS

📣 MPN Pathways: Empowered Voices in Research Webinar 
Session 5: Patient and Caregiver Voices in Research  

🗓 Aug 14 | 5–6 PM CST 

Featuring Patty Spears, BS, FASCO – leading cancer research advocate. 

🔗 Register: https://goto.mpnresearchfoundation.org/4knHgqZ 
 
#MPN #PatientAdvocacy #MPNVoices

MPNs are dynamic — new symptoms, changing blood counts, spleen enlargement. 

Even subtle shifts may raise the risk of disease progression, which looks different from patient to patient. Symptom tracking matters. 

#MPNs #RealWorldEvidence #Myelofibrosis #PV #ET @MPNResearch

20 years after her ET diagnosis, MJ Tooey’s journey is one of research, resilience & trust. From treatment setbacks to advocacy wins, her care team partnership made all the difference.  

Read her story here: https://mpnresearchfoundation.org/patient_stories/mj/

#MPNs #PatientVoice #MPNCommunity

Pruritus = 2nd most common symptom in #PV + #ET, 4th in #MF (2024 MPNRF Unmet Needs Survey). Once seen as PV-only, we now know itching affects all #MPNs — and it’s underrecognized. It can impact sleep, mood & clot risk.

It’s time we take it seriously.
#MPNsymptoms #BloodCancer

#MPN cells may resist #JAK2 inhibitors by rerouting growth signals. Combining ruxolitinib with other pathway inhibitors could block this escape route and delay resistance.
 
Sources: (Meyer & Levine, 2014; Stivala et al., 2019; Schnoeder et al., 2021; Brkic et al., 2021)

Living with myelofibrosis (MF) in the U.S.? 

Take a 5–7 min survey to share your experience and help improve MF community support! 

📝 https://www.tfaforms.com/5183605 
🔒 Confidential & for research 
Learn more: mappingmf.com
 
#Myelofibrosis #MPN #MappingMF

We are sharing a new #CME activity from @Medscape. It is designed to help you apply evidence-based strategies when caring for patients with #myelofibrosis (MF).

Let the #MF experts guide you through choosing the best therapies for complex cases! https://goto.mpnresearchfoundation.org/4gN7XTu

👏 We’re proud to support the #MPNHeroes Recognition Program by @VoicesofMPN.

This year, MPN Research Foundation’s Director of Patient Engagement, Sara Douglas, was honored to serve as a judge — helping recognize the inspiring contributions of this year’s heroes.

#MPNCommunity #PatientAdvocacy

💡 Only 48% of MPN patients feel they have enough emotional support.

Living with an MPN is emotional, not just physical. No one should face it alone.

Explore support resources: https://mpnresearchfoundation.org/subscribe-to-our-newsletter/

#MPNAwareness #PatientSupport #MentalHealthMatters #MPN

We’re celebrating 25 years of MPN progress by honoring our founder, Bob Rosen. 💙 

Join our webinar tomorrow to learn how you can support the next 25 years of life-changing blood cancer research. 

5 PM CT 
https://goto.mpnresearchfoundation.org/402Cjfd

#MPNResearch #LegacyGiving

Why do some MPNs progress? 

Scientist like Dr. Anandi Krishnan measure MPN mutant cell dysfunction to get answers: “Quality control is gone” — like “a factory where the pace has increased so much that the protein folding machinery is going awry.” 

#MPNProgression #MPNs

Young. Thriving. Overlooked.

Dana Turner is redefining what it means to live with a myeloproliferative neoplasm (MPN) — and why younger patients must be seen and heard.
 
Join our community and read her story: https://mpnresearchfoundation.org/subscribe-to-our-newsletter/
 
#MPN #PatientVoices

What do kidneys have to do with #MPNs?

A clinical trial hold-up led Dr. Brandi Reeves to a new theory: MPNs may trigger silent kidney damage through clotting signals in neutrophils.

She's testing it. 🔗 Read more: https://goto.mpnresearchfoundation.org/4kNfjsw

#MPNChallenge @UNC_Health #hematology

Join us today, 5–6 PM CST for FDA 101 — a crash course on how the FDA works and how MPN patients & caregivers can engage in the drug approval process. Featuring FDA expert Sarah Wicks. 

🔗 Register: https://goto.mpnresearchfoundation.org/4knHgqZ 

#MPN #FDA101 #PatientVoices #DrugDevelopment

Meet Andrea Spica: MPN patient and 7-year post-transplant recipient turned advocate.

From clinical trials to @MPN_RF Patient Impact Council, her journey fuels hope, research & support for others.

Read more: https://mpnresearchfoundation.org/patient_stories/andrea/

#MPNAdvocate #PatientSupport

Thank you to everyone who donated to #FoundationForward — you're powering patient-driven research and honoring Bob Rosen’s legacy. 

⏳ Today’s the last day to give. 

Let’s finish strong. 
📥 Donate now: https://goto.mpnresearchfoundation.org/4js24x1 

#MPNResearch #RareDisease #LastDayToGive

25 yrs ago, MPNs had no research roadmap.

Then came Bob Rosen.

His first grant helped lead to the discovery of JAK2 in 2005 — a breakthrough that changed everything.

We're moving #FoundationForward.
Join us: https://goto.mpnresearchfoundation.org/425ellc

#MPNResearch #RareDisease #BobRosenLegacy

MPN patients + caregivers: Join us June 5 for FDA 101, a free webinar on how the FDA approves treatments — and how YOU can get involved. Recording included! 

⏰ 5–6PM CT
🔗 Register: https://us02web.zoom.us/webinar/register/7917435180461/WN_MSZktPYUQpmI_vLodw38og 

#MPNVoices #FDA101 #MPNPathways

72% of MPN patients are unaware of the MPN 10 symptom-tracking tool. 

We're moving #FoundationForward by raising awareness. 
💬 Ever used it? Heard of it? Tell us below! 

📥 Subscribe for updates: https://mpnresearchfoundation.org/subscribe-to-our-newsletter/
#MPNResearch #RareDisease

627 voices. 31 countries. 1 shared mission. 

From Bob Rosen’s vision to global momentum — the global response to our Unmet Needs Survey is shaping the future of MPN research. 

👉 Reply with your country & join the movement.

In 1997, Bob Rosen was diagnosed with PV — and found no roadmap. So, he built one. 

25 years later, we’re moving #FoundationForward, empowering patients with research, resources, and support. 

📥 Join our community: https://goto.mpnresearchfoundation.org/425ellc
 #MPNResearch #RareDisease

What’s a citation trail? It’s when one study sparks another — and another... 

MPN Research Foundation has funded research with rich citation trails that stretch from years ago to today’s most promising advances. 

Join us: https://goto.mpnresearchfoundation.org/425ellc
#MPNResearch #CitationTrail