Nathan J. O'Connor, PhD, MS's Avatar

Nathan J. O'Connor, PhD, MS

@nateoconnor.bsky.social

I love food, dogs, science, and good people. #neuroscience #cellbio I'm a scientist at MBF Bioscience and views expressed are my own.

421 Followers  |  481 Following  |  44 Posts  |  Joined: 03.12.2024
Posts Following

Posts by Nathan J. O'Connor, PhD, MS (@nateoconnor.bsky.social)

photo of Pam Bondi testifying in the foreground as a group of 7 women and 1 men raise their hands

photo of Pam Bondi testifying in the foreground as a group of 7 women and 1 men raise their hands

Likely-historic photo by NBC News of all the Epstein victims asked to raise their hands if they've not yet been asked to meet with the DOJ as Bondi testifies in foreground

11.02.2026 17:15 β€” πŸ‘ 40538    πŸ” 13812    πŸ’¬ 1374    πŸ“Œ 891

I've noticed that #conspiracy buffs have the interesting ability to passionately describe outliers as the norm.

05.02.2026 23:29 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Hybrid Solid-Liquid Optics Enable Scalable, High-Resolution, Multi-Immersion Light-Sheet Microscopy Modern biology increasingly depends on data-driven discovery, requiring scalable and affordable high-content 3D imaging across molecular to organ scales. Although tissue clearing, expansion microscopy...

Proud to be a part of this transformative work from the Tomer Lab & @mbfbioscience.bsky.social πŸ”¬

HySIL & SCOPE are the framework that power the new SLICE light-sheet microscope. πŸš€

Submicron resolution, multi-immersion, and affordability:
www.biorxiv.org/content/10.1...

#Microscopy #LightSheet

19.11.2025 20:09 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Big data in microscopy shouldn't be a bottleneck.

I started Arnas Technologies arnastech.com to solve exactly that. We build custom #AI workflows to automate analysis for #lightsheet, #microscopy, and #OMICS data.

#BioTech #DataScience #ImageAnalysis #BioImageAnalysis

19.11.2025 19:16 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

🎨 You’re invited to an Evening of Art and Ideas!

Experience science and creativity over appetizers, drinks, and the exhibition Umwelt: Phenomenal Worlds, exploring perception and consciousness.

πŸ“ UC San Diego Park & Market
πŸ—“οΈ Sun, Nov 16 | 6–9 PM

✨ We hope to see you there!

11.11.2025 20:19 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Video thumbnail

First real-time human embryo implantation recorded (in 2D and 3D). Time lapse video of 2 embryos (200 ΞΌm apart) implanting in the 3D platform
science.org/doi/10.1126/...

15.08.2025 19:39 β€” πŸ‘ 220    πŸ” 45    πŸ’¬ 7    πŸ“Œ 2

Amazing! The top looks like transmitted light microscopy. And the bottom is reflectance imaging so you can see the collagen matrix, right (from reading the paper)?

15.08.2025 19:49 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
A Practical Guide to Selecting Compression Levels for 3D Light Sheet Fluorescent Microscopy Data A white paper outlining practical strategies for managing the large data volumes generated by 3D light sheet fluorescence microscopy, with a focus on selecting compression levels that balance file siz...

Lightsheet microscopy produces terabytes of image data quicklyβ€”creating storage, transfer, and analysis bottlenecks. In my work, I’ve found smart compression strategies to be essential. Here are some of my observations:
figshare.com/articles/pre...

#microscopy @mbfbioscience.bsky.social

13.08.2025 19:41 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Checkout this webinar (8-6-25; 12pm EDT) on the SLICE light sheet microscope from @MBFBioscience! This high performance system is the size of a microwave and costs less than most confocals. I've loved working on this democratizing leap in #microscopy. #goodStuff #neuroscience

29.07.2025 21:49 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Checkout this webinar (8-6-25; 12pm EDT) on the SLICE light sheet microscope from @mbfbioscience.bsky.social! This high performance system is the size of a microwave and costs less than most confocals. I've loved working on this democratizing scientific leap in #microscopy #goodStuff #neuroscience

29.07.2025 21:37 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

My #capybara friend is helping me register brains to Dr. Kim's devCCF (kimlab.io/brain-map/De...) atlas based on the CCF mouse brain atlas from the @alleninstitute.org. @mbfbioscience.bsky.social I'm, of course, using NeuroInfo for registration and cell counting :) #neuroScience

16.06.2025 22:35 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Chunky black bean corn #salsa to go with quesadillas made from leftover lean grilled to sirloin. #easycooking

04.06.2025 22:49 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Our abstract for #SfN25 is in! #neuroscience @mbfbioscience.bsky.social #science #brains #connectomics #microscopy

04.06.2025 18:40 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Preview
Protecting the Future of Biomedical Research: A Call to Defend NIH Funding Join us to defend scienceβ€”write, call, and speak up. Biomedical research must be protected; the cost of inaction is too high for human lives.

Protect the future of biomedical research!
www.mbfbioscience.com/news/2025/03...

@mbfbioscience.bsky.social @alleninstitute.bsky.social #science #neuroscience @mcuban.bsky.social

06.03.2025 20:35 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Preview
Calling BS: Live-chat and Prebuttal to Trump's Address Β· MoveOn A better Tuesday and country are possible! As Trump hawks an hour of lies and dangerous directives to Congress, MoveOn is providing an antidote: a livestream event with Senators Chris Murphy and Brian...

mobilize.us/s/oe8p8j

04.03.2025 22:51 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

#BrainAwarenessWeek is almost here! 🧠✨ We're considering hosting some Bluesky chats to bring the #Neuroskyence community together. Would this be something you would join in on? What would you ask the community?

20.02.2025 22:48 β€” πŸ‘ 29    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Post image

Um... didn't the #USA have a revolution or something just to not have a king? #SMH

19.02.2025 23:09 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Portuguese editorial cartoonist Zez Vaz reaches back to Tiananmen Square to call on American defiance.

15.02.2025 13:43 β€” πŸ‘ 50509    πŸ” 16409    πŸ’¬ 515    πŸ“Œ 1149
Post image

Stuart got us these bands for #valentinesday. Solid as metal together. No matter what happens in these crazy times, nothing will break us. #LGBT #civilrights

15.02.2025 21:23 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Reporting methods for reusability - Nature Methods Proper methods reporting is crucial for transparency, but ensuring method reusability by other labs takes a bit of extra effort. Here we discuss best practices for reporting methods so that they can b...

In this month's Editorial, we discuss best practices for reporting methods so that they can be reused by other labs. Read it here!
www.nature.com/articles/s41...

11.02.2025 18:45 β€” πŸ‘ 18    πŸ” 12    πŸ’¬ 0    πŸ“Œ 0
Post image

Why does the world's richest man want to gut the CFPB?

Because it would shield him from having to follow financial laws to keep customers' money safe β€” and give him access to confidential records about his competitors.

Follow the money.

10.02.2025 17:26 β€” πŸ‘ 5664    πŸ” 1904    πŸ’¬ 214    πŸ“Œ 96
Preview
Drunk Driving | NHTSA Get resources on ways to prevent drunk driving and alcohol-impaired crashes along with national drunk driving statistics and facts.

I know it's an awesome day for celebration (#superbowl), but please don't #DrinkAndDrive. I've lost a brother and a brother-in-law to drunk drivers. Ubers and taxis are so easy to get. www.nhtsa.gov/risky-drivin...

09.02.2025 22:50 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image Post image

JD Vance, a Yale Law graduate, doesn't understand Marbury v. Madison, the most famous case in Constitutional law, which established judicial review of the other two branches of government.

09.02.2025 20:22 β€” πŸ‘ 5614    πŸ” 1573    πŸ’¬ 415    πŸ“Œ 91
Preview
Puppy Bowl

Love this. I love our rescue pup. #adoptDontShop #puppyBowl www.discovery.com/shows/puppy-...

09.02.2025 20:24 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
JD Vance Suggests Judges β€˜Aren't Allowed’ To Control Trump After Courts Block His Policies A slew of court rulings in recent weeks have hampered the Trump administration’s moves on issues like birthright citizenship and shutting down USAID.

So much for the #GOP being the party of "law and order"... and this is from Forbes. #JDVance www.forbes.com/sites/alison...

09.02.2025 20:07 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

He's definitely a bit flighty on #science.

08.02.2025 02:08 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

It will be his "Let's go Brandon". He deserves it.

08.02.2025 01:55 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Microplastics in the bloodstream can induce cerebral thrombosis by causing cell obstruction and lead to neurobehavioral abnormalities Microplastics get in the blood and are eaten by immune cells, leading to cell obstruction and cerebral thrombosis.

There seems to be a growing body of research on the #brain and #microplastics. scholar.google.com/scholar?hl=e...

This is an interesting article from that search: www.science.org/doi/abs/10.1...

#neuroscience #microscopy

07.02.2025 22:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

That is some awesome data for that probe. Very cool! #microscopy

06.02.2025 21:56 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
February 5, 2025
YouTube video by Tammie Eller February 5, 2025

@thedailyshow.com @msnbc.com Please cover #bigots like this. @margaretcho.bsky.social

www.youtube.com/shorts/8uv2J...

06.02.2025 03:02 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0