Alexey Strygin

Full research, and what would actually move the needle: open.substack.com/pub/strygin/...

This is my first Substack post. Subscribe if you want more.

Full research: open.substack.com/pub/strygin/...

The funding gap is staggering.
246 billionaires worth $1.56T died of aging this decade.
Total ultra-wealthy investment in longevity over 25 years? $5B (according to
@wsj.com)
The average billionaire who died of aging held more wealth than the entire field's funding.

After 90, any advantage billionaires have disappears entirely.
Billionaire mortality at 90+ is statistically indistinguishable from leading life expectancy countries
The Gompertz curve doesn't care about your net worth.

So how much does being a billionaire buy men? 0-4 extra years beyond the world's healthiest population. Why such a wide range? It's complicated: selection bias, survivor effects, and pre-death wealth loss. Read the full study.

It sucks to be a female billionaire.
Female billionaires die 4.5 years EARLIER than the leading benchmark. The usual 5-7 year female longevity advantage nearly vanishes. Male and female billionaires die at about the same age. No country on Earth shows a gap this small.

6 helicopter crashes in a decade, in a population of a few thousand.
Helicopters are used to compress travel time. For 6 billionaires, they compressed life instead.

90% of billionaires die of an aging-related disease, or "peacefully," "in their sleep," "surrounded by family." All euphemisms for aging doing what aging does.

Caveat: among deaths with known cause. 30% have no publicly disclosed cause (True wealth is quiet)

I tracked every billionaire who died in the last decade.
389 deaths. $2.17 trillion in wealth. 6 helicopter crashes.
Here's what I found.

Subscribe to get it when it drops: substack.com/@strygah

I'm launching a Substack next week with a piece I've been working on for two months. Original research on billionaire ... (can you guess what?)

I used to need alcohol as a social lubricant when I was younger.

Now I'm the social lubricant myself.

YouTube video by Elias Schlie (Longevity) We build a Longevity Pop-up City - Zelar.city team interview

🚨🚨🚨
Reflections on Zelar.City are out! The organizing team was
interviewed during the final days of the 5-week event and daily deep convos

We reflect on longevity industry and pop cities

A MUST SEE

www.youtube.com/watch?v=T5pc...

Is it just me, or am I uncovering new reasons to pursue radical life extension? 🤔

(Of course, we're talking about biological age in theoretical high calendar-year-old 25-year-olds!)

Paper for reference:
doi.org/10.1101/cshp...

1️⃣ It's way better to be a woman!
2️⃣ If you're a man lucky enough to live to 5,000 years, you're in a world where there are three 25-year-old Japanese women for every one of you!
3️⃣ If you've made it to 10,000 years, the number of women per man is ~7.5.

3️⃣ We also know there are big differences between male and female mortality rates. I found the mortality rates for 25-year-olds in Japan (0.02% for women, 0.04% for men) and plotted a graph. What do we observe?

2️⃣ There's a huge variation in lifespan (see the survival curve I modeled):

Half the people will die before reaching 1,214.5 years
18% will live up to 3,000 years
5.78% will make it to 5,000 years
0.33% will reach 10,000 years

1️⃣ Even when we remove aging from the equation, there are still chances of dying (from infections, violence, accidents, and cancers). For 30-year-olds, the mortality rate in the paper is about ~0.057% per year, aligning with data from developed countries like Japan.

Reversing one year of aging per year essentially hits the Longevity Escape Velocity point. In this scenario, the expected lifespan for 30-year-olds is 1,782.6 years.

Way better than now!

But there are important nuances (I played around with the data for you): 📊

I've been digging into Andrew Scott's paper and found an interesting table modeling a theoretical therapy applied once a year that regenerates either 1 year, 9 months, 6 months, or 3 months of aging at different ages (see table).
🧵

My pronouns are “fuck/death”

Who is here from longevity biotech?

How do get banned here? Can I joke?