Alexey Strygin's Avatar

Alexey Strygin

@strygah.bsky.social

founder, executive, vitalist 🧬 longevity biotech, longevity economics, drug discovery, startups

92 Followers  |  17 Following  |  12 Posts  |  Joined: 25.11.2024  |  1.4159

Latest posts by strygah.bsky.social on Bluesky

I used to need alcohol as a social lubricant when I was younger.

Now I'm the social lubricant myself.

14.02.2025 12:06 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1
We build a Longevity Pop-up City - Zelar.city team interview
YouTube video by Elias Schlie (Longevity) We build a Longevity Pop-up City - Zelar.city team interview

🚨🚨🚨
Reflections on Zelar.City are out! The organizing team was
interviewed during the final days of the 5-week event and daily deep convos

We reflect on longevity industry and pop cities

A MUST SEE

www.youtube.com/watch?v=T5pc...

23.12.2024 16:46 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
International Gains to Achieving Healthy Longevity

Is it just me, or am I uncovering new reasons to pursue radical life extension? πŸ€”

(Of course, we're talking about biological age in theoretical high calendar-year-old 25-year-olds!)

Paper for reference:
doi.org/10.1101/cshp...

04.12.2024 17:28 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

1️⃣ It's way better to be a woman!
2️⃣ If you're a man lucky enough to live to 5,000 years, you're in a world where there are three 25-year-old Japanese women for every one of you!
3️⃣ If you've made it to 10,000 years, the number of women per man is ~7.5.

04.12.2024 17:28 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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3️⃣ We also know there are big differences between male and female mortality rates. I found the mortality rates for 25-year-olds in Japan (0.02% for women, 0.04% for men) and plotted a graph. What do we observe?

04.12.2024 17:28 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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2️⃣ There's a huge variation in lifespan (see the survival curve I modeled):

Half the people will die before reaching 1,214.5 years
18% will live up to 3,000 years
5.78% will make it to 5,000 years
0.33% will reach 10,000 years

04.12.2024 17:28 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

1️⃣ Even when we remove aging from the equation, there are still chances of dying (from infections, violence, accidents, and cancers). For 30-year-olds, the mortality rate in the paper is about ~0.057% per year, aligning with data from developed countries like Japan.

04.12.2024 17:28 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Reversing one year of aging per year essentially hits the Longevity Escape Velocity point. In this scenario, the expected lifespan for 30-year-olds is 1,782.6 years.

Way better than now!

But there are important nuances (I played around with the data for you): πŸ“Š

04.12.2024 17:28 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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I've been digging into Andrew Scott's paper and found an interesting table modeling a theoretical therapy applied once a year that regenerates either 1 year, 9 months, 6 months, or 3 months of aging at different ages (see table).
🧡

04.12.2024 17:28 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

My pronouns are β€œfuck/death”

29.11.2024 19:00 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Who is here from longevity biotech?

25.11.2024 21:09 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

How do get banned here? Can I joke?

25.11.2024 20:56 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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