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Anna Lehmann

@aelehmann.bsky.social

PhD candidate in the Heitman lab @dukemedschool studying genetics of antimicrobial resistance in fungal pathogens | @dartmouthartsci alum | runner, skier, outdoor enthusiast

26 Followers  |  59 Following  |  1 Posts  |  Joined: 09.08.2025  |  1.4302

Latest posts by aelehmann.bsky.social on Bluesky

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Whole-chromosome duplications drive antimicrobial resistance in Aspergillus fumigatus Aneuploidy causes genome plasticity and enables adaptive responses that confer drug resistance in eukaryotes ranging from fungal pathogens to human cancer cells. Aspergillus fumigatus is a soil-reside...

Excited to share our new preprint in collaboration with @kellerlab.bsky.social! We identified unstable aneuploidy in Aspergillus fumigatus and explore how aneuploidy-mediated transcriptional and metabolic changes influence antifungal resistance.

www.biorxiv.org/content/10.1...

04.10.2025 21:53 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Extremely excited to present our latest preprint in which we mapped a thermoregulation network that governs virulence in a human fungal pathogen through genetic suppressors, TurboID proximity ligation assay, and functional regulation via domain-truncation alleles.
www.biorxiv.org/content/10.1...

20.08.2025 03:00 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Population structure in a fungal human pathogen is potentially linked to pathogenicity Nature Communications - Genetic diversity between clinical and environmental fungal isolates of Aspergillus flavus is poorly studied. Here, the authors analysed genomic data from a global set of...

Thrilled to share that the final chapter of my PhD with @rokaslab.bsky.social is now out in @natcomms.nature.com ๐ŸŽ‰
Read it to find out how population structure impacts pathogenicity in Aspergillus flavus, a fungus that infects humans ๐Ÿงช
rdcu.be/eAToj

18.08.2025 21:48 โ€” ๐Ÿ‘ 51    ๐Ÿ” 20    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3
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Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host - Nature Microbiology A mycovirus infecting the pathogenic fungus Aspergillus fumigatus enhances its stress tolerance and virulence in mice.

๐Ÿšจ Fungi + viruses + mammalian lungs? Buckle up! Our new paper in
@natmicrobiol.nature.com
uncovers the story of a deadly fungus and its gnarly viral hitchhiker โ€” and how this duo may change how we diagnose & treat fungal disease ๐Ÿ„๐Ÿซ๐Ÿšจ doi.org/10.1038/s415... โฌ‡๏ธ

14.08.2025 09:46 โ€” ๐Ÿ‘ 93    ๐Ÿ” 43    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 6

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