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Freya Allen

@freyaallen.bsky.social

PhD student at the University of Birmingham | AMR, evolution and enterococci

63 Followers  |  84 Following  |  2 Posts  |  Joined: 17.11.2023  |  1.5869

Latest posts by freyaallen.bsky.social on Bluesky

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Resistance to last-resort antibiotics in enterococci Abstract. The genus Enterococcus comprises a diverse group of species, many of which are commensal members of the gut microbiota of humans and animals. The

Delighted that our review on resistance to last-resort antibiotics in Enterococci has been published in FEMS Microbiology Reviews

academic.oup.com/femsre/advan... (accepted manuscript version)

TL;DR: the Enterococci are really good at evolving resistance to antibiotics in new and creative ways.

08.11.2025 17:41 โ€” ๐Ÿ‘ 56    ๐Ÿ” 25    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 1

Thanks Ross!!

10.11.2025 08:46 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks Lisa!

10.11.2025 08:45 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
From left to right: Willem, Freya, Jess and Rob.

We are standing in front of a wall with a congratulations banner and some left-over Halloween decorations.

From left to right: Willem, Freya, Jess and Rob. We are standing in front of a wall with a congratulations banner and some left-over Halloween decorations.

Absolutely delighted (and proud) that @freyaallen.bsky.social passed her viva with minor corrections today.

Thanks very much @jessicamablair.bsky.social @robfagan.bsky.social for examining!

06.11.2025 22:09 โ€” ๐Ÿ‘ 45    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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Genome co-adaptation and the evolution of methicillin resistant Staphylococcus aureus (MRSA) Background: Antimicrobial resistance (AMR) in bacterial pathogens is a major threat to global health, rendering standard treatments ineffective and increasing the risk of severe infection or death. Re...

๐ŸšจNew pre-print ๐Ÿšจ
We introduce our new tool GOLD-GWAS and demonstrate its use by digging into the evolution of MRSA facilitated by SCCmec

This work was led by talented PhD student @seungwonko.bsky.social who did most of the computational heavylifting 1/n

www.biorxiv.org/content/10.1...

23.07.2025 10:50 โ€” ๐Ÿ‘ 22    ๐Ÿ” 12    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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PNGaseA-mediated N-glycan stripping from peptides by infant-derived Bifidobacterium bifidum N-glycans are highly common sources of nutrition for human colonic-dwelling bacteria. These microbes have evolved a several methods to remove N-glycans from proteins; herein we describe the biochemica...

๐Ÿšจ New preprint klaxon ๐Ÿšจ
We characterised the structure of a PNGaseA superfamily member from Bifidobacterium bifidum LMG13195 and highlight its preference for N-glycan structures attached to a peptide, rather than to a native or denatured protein ๐Ÿ’ซ @imibirmingham.bsky.social

18.07.2025 11:22 โ€” ๐Ÿ‘ 13    ๐Ÿ” 4    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium pRUM-like plasmids are commonly found in multidrug-resistant Enterococcus faecium , but the evolution of these plasmids has not been characterised in detail. When we analysed the genome sequences of t...

New manuscript from the group

'IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium'

www.biorxiv.org/content/10.1...

/1

17.07.2025 08:39 โ€” ๐Ÿ‘ 28    ๐Ÿ” 13    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 2

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