Tej's Avatar

Tej

@scienthusiast.bsky.social

Proteomics, Mass Spectrometry

577 Followers  |  253 Following  |  278 Posts  |  Joined: 22.09.2023
Posts Following

Posts by Tej (@scienthusiast.bsky.social)

Preview
Faces of Mass Spectrometry/Bini Ramachandran

Faces of Mass Spectrometry/Bini Ramachandran #JASMS pubs.acs.org/doi/10.1021/...

20.02.2026 14:02 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

All values (high intensity and low intensity) need to be within the linear dynamic range of the instrument platform to be safely adjusted by software normalizations. Overloaded samples suffer saturation, underloaded samples have things go below limits of detection. There are no shortcuts in life.

16.02.2026 22:52 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Post image

Astral with 2 minute gradients! More quantification off of triangles! www.nature.com/articles/s41... - I get it, I'm being the old jerk shouting at cars about how in my day we had to have more than 1 scan/peak.

16.02.2026 21:02 β€” πŸ‘ 17    πŸ” 1    πŸ’¬ 5    πŸ“Œ 0
Course at EMBL-EBI. Proteomics bioinformatics. 6 - 10 July 2026. Hinxton, UK. EMBL's European Bioinformatics Institute logo.

Course at EMBL-EBI. Proteomics bioinformatics. 6 - 10 July 2026. Hinxton, UK. EMBL's European Bioinformatics Institute logo.

Proteomics bioinformatics by EMBL-EBI Training is the course for you if you want to discover:

- Mass spectrometry
- Quantitative proteomics
- Data acquisition approaches
- Proteogenomics
- @emblebi.bsky.social resources: IntAct, PRIDE, and UniProt

Apply by 15 March: www.ebi.ac.uk/training/eve...

11.02.2026 14:39 β€” πŸ‘ 5    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0
Preview
DEprot: a comprehensive R-package for the analysis of label-free quantitation mass spectrometry data Abstract. In recent years, studies investigating protein–protein interactions on a proteome-wide scale have increased exponentially. These developments wer

πŸ’‘β€œDEprot” is now out on @narjournal.bsky.social Genomics and Bioinformatics.
With Nils Eickhoff ( @zwartlab.bsky.social, @nkinl.bsky.social & @oncodeinstitute.bsky.social), we designed this β€œall-in-one” tool to facilitate the analyses of LFQ-based proteomics data.

academic.oup.com/nargab/artic...

11.02.2026 23:32 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 2    πŸ“Œ 0
Home - Trost Lab

I have a 3-year postdoc position available at University of Manchester for a mass spec expert in proteomics. The person will be involved in exciting projects in single cell proteomics, drug discovery and innate immunity - on timsTOF Ultra AIP & HF & Astral Zoom.

www.jobs.ac.uk/job/DQJ093/r...

02.02.2026 19:52 β€” πŸ‘ 24    πŸ” 27    πŸ’¬ 0    πŸ“Œ 0
Video thumbnail

Want to make your DIA-NN QC reports in a web browser and then go back in time to the 80's and 90's? Now you can with my completely AI vibe coded streamline app! dia-nn-qc.streamlit.app You're welcome 😜

27.01.2026 23:46 β€” πŸ‘ 20    πŸ” 4    πŸ’¬ 4    πŸ“Œ 2
Post image

Special Issue on Women in Proteomics www.mcponline.org/ar...

---
#proteomics #prot-paper

22.01.2026 09:40 β€” πŸ‘ 5    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0
Post image

Yasset Perez-Riverol | This chart is a warning light for anyone in science or tech.

www.linkedin.com/pos...

---
#proteomics #prot-other

18.01.2026 09:20 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Post image

A New Detailed Mass Offset Search in MSFragger for Improved Interpretation of Complex PTMs pubs.acs.org/doi/10....

---
#proteomics #prot-paper

14.01.2026 15:01 β€” πŸ‘ 11    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Also good to know, it wasn't just me wondering why MAPS was left out..

15.01.2026 06:56 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
New mass spectrometry technique captures low-abundance molecules A new mass spectrometry technique captures molecules of lower abundance in a sample, providing a more comprehensive sample profile.

Saw the same on biotechniques, atleast they cited the article in the press release. But, yeah, the press release was ambiguous with no specifics
www.biotechniques.com/analytical-c...

15.01.2026 06:53 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Limited proteolysis-coupled mass spectrometry captures proteome-wide protein structural alterations and biomolecular condensation in living cells link.springer.com/ar...

---
#proteomics #prot-paper

13.01.2026 18:40 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Post image

News in Proteomics Research blog post | Finally! A ready-to-run human plasma proteomics standard! proteomicsnews.blogs...

---
#proteomics #prot-other

07.12.2025 17:00 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
Post image

PhD Fellow in Spatial Proteomics of Cardiac Conduction and Disease Mechanisms | JobTeaser www.jobteaser.com/nl...

---
#proteomics #prot-jobs

05.12.2025 17:40 β€” πŸ‘ 0    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

Multi spectral imaging at UV and IR range to mark sampling zones..and followed it up with hydrophobic ion-ion interaction to identify peptides.. old vs new peptides distinguished by monitoring of oxidation and deamidation.. sleuths at work..#paleoproteomics

29.11.2025 10:39 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Jobs Jobs at VIB Technologies

🚨 Job opportunity
The Proteomics Core is hiring a (Junior) Technical Support Team Member to keep its mass-spec proteomics services running smoothly.

πŸ—“ Deadline: November 30, 2025
πŸ‘‰ Apply via the VIB job site https://vib.be/en/technologies/about-vib-technologies/jobs#/job-description/127269

28.11.2025 15:10 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Utrecht University is hiring:
Postdoc Position in Proteomics and Immuno-Oncology

16.11.2025 06:50 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Preview
R/Bioconductor for Mass Spectrometry and Proteomics Dates 17-19 November 2025 To foster international participation, this course will be held online

πŸŽ“ Upcoming Online Course: R/Bioconductor for Mass Spectrometry & Proteomics

πŸ“… November 17–19, 2025

Join Dr Laurent Gatto for a hands-on course on mass spectrometry–based proteomics analysis using R and Bioconductor.

πŸ‘‰ Register & learn more: www.physalia-courses.org/courses-work...

06.11.2025 10:00 β€” πŸ‘ 14    πŸ” 8    πŸ’¬ 0    πŸ“Œ 1
Doing Differential Expression analysis on Proteomics Data using Limpa!!
YouTube video by Brett Phinney Doing Differential Expression analysis on Proteomics Data using Limpa!!

Need to do some cutting edge Proteomics Differential expression? Maybe give Limpa a try! Guaranteed to rise to the occasion ...despite its name !

youtu.be/vqeOT8xcycc

27.10.2025 17:03 β€” πŸ‘ 17    πŸ” 4    πŸ’¬ 3    πŸ“Œ 0

Some new content at GitHub:

github.com/pwilmart/pow...

We have been measuring proteomes for a long time but almost never think about our data and results at the whole proteome level. We lose a lot of information when we think one protein at a time. We need to multiplex our thinking.

27.10.2025 23:29 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 3    πŸ“Œ 0
Post image

Are you having a LaPh? Diverse roles of Labile Phosphorylation in mammalian cells portlandpress.com/bi...

---
#proteomics #prot-paper

23.10.2025 11:00 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

"... if we're competitive from a price, thoughput and coverage perspective, the other technologies seem more than a bit silly. " That sums it upπŸ‘πŸΎ

19.10.2025 10:57 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Enrichment of Cysteine S-palmitoylated peptides using Sodium Deoxycholate Acid Precipitation www.mcponline.org/ar...

---
#proteomics #prot-paper

19.10.2025 09:00 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Post image

Struggling to compare Bruker timsTOF methods or extract window schemes from raw .d files? I developed a free desktop tool to solve this: timsCompare! πŸš€

It automates the manual work of extracting method parameters, presenting them in a structured and comparable view.

(A thread 🧡)

15.10.2025 11:01 β€” πŸ‘ 24    πŸ” 9    πŸ’¬ 2    πŸ“Œ 1
Post image

Postdoctoral Fellow to study host-virus responses using proteomics and mass spectrometry stilling.forskning.n...

---
#proteomics #prot-jobs

14.10.2025 09:00 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Preview
Twenty-Five Years of High-Throughput Screening of Biological Samples with Mass Spectrometry: Current Platforms and Emerging Methods Robust high-throughput screening (HTS) approaches for discovering new chemical entities are desirable for research and translation. Applications for which high-throughput (HT) methods are particularly...

Twenty-Five Years of High-Throughput Screening of Biological Samples with Mass Spectrometry: Current Platforms and Emerging Methods #AC pubs.acs.org/doi/10.1021/...

09.10.2025 18:44 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Post image

Boosting the speed and accuracy of protein quantification algorithms in mass spectrometry-based proteomics www.biorxiv.org/cont...

---
#proteomics #prot-preprint

09.10.2025 08:20 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Post image

PhD Position in Experimental Mass Spectrometry-Based Proteomics | JobTeaser www.jobteaser.com/fr...

---
#proteomics #prot-jobs

07.10.2025 21:20 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Okay y’all. I’m at a complete loss. DIA is better on EVERYTHING on my Ultra2 except plasma digests. Neat, PC, PCA-N. DDA (pasef) works better. Coisolation FDR artifact? Anyone else see this?

06.10.2025 19:52 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 3    πŸ“Œ 0