Maik Bischoff

must*

Thank you! I nust say, I haven't drawn it myself though. I know this picture for years, but I don't even know who the artist is. There used to be a "Drosophila Drawings" website with many cartoons like that one, I think.

#FlyCROSS mentee surveys are open for #earlycareer #Drosophila scientists. If you're a #gradstudent #postdoc or pretenure faculty or equivalent - fill up the survey by Sept 1 to participate & be matched by #mentor of your preferences to gain guidance to your unique needs. @flybase.bsky.social

Fig. 2. Elongation behaviors of isolated and recombined explants in different conditions. (A) Table of isolation and recombined tissue experiments. Tissues are isolated with Activin or not and tested for elongation in isolation or recombined. This yields a total of eight conditions. (B-C′) Isolated mesenchyme and epithelial tissue experiments and their respective aspect ratio plots. N=5. (D-G′) Recombination experiments and their respective plots. Data are mean±s.d. N=5 for all conditions. Scale bars: 100 µm

Explant elongation initiates in the epithelium

A Research Highlight showcasing new work from @katiabarrett.bsky.social, Shalabh Anand, Virginie Thome, Laurent Kodjabachian, @merkellab.bsky.social, @pflenne.bsky.social

journals.biologists.com/dev/article/...

This thread below is criminally under-liked and under-shared!

Young #Drosophila researchers (PhDs, postdocs, and early-career Drosophilists): fill out the survey by Sept 1st to get matched with a mentor who can support you with your career.

Established Drosophilists, like/share Shefali's Thread ;)

Fantastic work by the Iber group!

Great opportunity here to build your skills and your professional network! Apply for the SciComm Interns program!
#devbiolwriteclub
@socdevbio.bsky.social

📌 Summary:

• #DCM is a rapid, robust mechanism for developmental pattern formation
• COMSOL FEM implementation makes DCM models numerically accessible
• #DCM patterning parameter ranges and timeframes
• Pattern Orientation via attraction anisotropy or directed tissue growth

👇Thread 🧵(10/11)

How can cells self-organize rapidly into complex patterns during development?

Let’s explore a powerful and underappreciated mechanism: Directed Cell Migration (DCM).

Preprint @biorxivpreprint.bsky.social : doi.org/10.1101/2025...

👇Thread 🧵(1/11)

A confocal image of an E18.5 mouse lung showing Shh-expressing cells in green and non-expressing cells in magenta. Image was acquired on a Nikon A1R.

Happy #MicroscopyMonday! Here is another gorgeous lung image from a Shh lineage tracing survey by @stjuderesearch.bsky.social postdoc Christina Daly! This is an E18.5 🐭 lung with magenta showing non Shh-expressing cell types and membrane GFP marking Shh-expressing cells. 🤩 🧪 🔬 👩‍🔬

first data from the new LLSM in PertzLab @olivierpertz.bsky.social! i always thought nuclei were spherical but they are pancakes???? so much more to see in 3d, but data volume produced is insane, we will have to rethink our analysis pipelines. tips welcome! here shown in @napari.org

Quantifying convergent extension: Shih and Keller's quintessential work in developmental cell biology Few biological fields have become more intertwined in recent years than cell and developmental biology, a fact made clear by the departments of cell a…

One the best things about a life in science is that your heroes often become your friends. My entire career stems from two papers by Ray Keller and I'm just thrilled to have a new piece out with Rob Huebner highlighting those classic papers.

www.sciencedirect.com/science/arti...

Looking for an opportunity to work on cutting super-resolution microscopy and AI? There's still time to apply to the two positions!

What does the Vienna BioCenter offer - Hear it directly from our fellows!

Sounds good? Apply now to join our Postdoc Program.

The VIP³ call is open–16 fully-funded, three-year postdoctoral fellowships in an interdisciplinary environment: training.vbc.ac.at/post-docs/vi...

#VBCPostDoc

Helen Weavers

Our latest interview is with 2025 @bscb-official.bsky.social WICB early career medal winner Helen Weavers @helenweavers.bsky.social‬. We hear about what winning the award means to Helen, her research and her advice on staying resilient.
journals.biologists.com/jcs/article/...

Finally! My PhD work is out in @jcb.org ❤️ thanks to everyone involved. It was a long way to this, but it was worth it.

If you’ve been following this account closely, you might already know methods to probe mechanics in vitro, but what about in live embryos?

I’m @amichaut.bsky.social, and I’m going to share a few great papers on this aspect of #EpithelialMechanics.

Image-activated cell sorting - Nature Reviews Bioengineering Genomic research has been transformed by genome databases, epigenetic discoveries and precise editing, yet linking genetic and epigenetic changes to cellular phenotypes remains challenging. In this Re...

nice combo approach!
www.nature.com/articles/s44...

It's one of those experiments where you don't really know if it's worth doing it but you're also curious to know what happens if you do it.
I adapted another Optogenetic tool in 🐸 that allows one to change the migration direction of immune cells. It works beautifully, but is it useful for me, Idk 😅

I would be glad to help!

Thank you so much, Angelo

🤩Thanks for sharing the featured 🔬image with us and putting up this beauty, so we can appreciate the full morphology of the hydei testis.🤩

Such an honor to be featured by @focalplane.bsky.social , especially on my favorite day of the week: #FluorescenceFriday! 🔬

Below for reference, a picture of the full hydei testis with the musculature stained (depth-coded) taken together with @saraheclark.bsky.social

#cellbio #devbio #microscopy

Featured image with Maik Bischoff - FocalPlane Featured image with Maik Bischoff - News

Our featured 🔬image this #FluorescenceFriday is of a portion of testis from Drosophila hydei, acquired by @maikbischoff.bsky.social.

Learn more about the image and Maik’s research ⤵️
focalplane.biologists.com/2025/07/18/f...

Yay! New paper out in PNAS: www.pnas.org/doi/10.1073/... . How do dynamical forces generated by tissue movement affect organ morphology changes during embryonic development?
Using Kupffer’s vesicle in zebrafish embryo we showed that dynamical forces produce shape changes in a developing organ.

YouTube video by The Late Show with Stephen Colbert A Scientific Brain Drain Has Followed Trump’s Gutting Of The NIH - Dr. Francis Collins

If you haven't seen this wonderful interview with Dr. Francis Collins, it's worth your time. Send to family and friends and #RT. #devbio @c4lifesciences.bsky.social

www.youtube.com/watch?v=lW9c...

How cells understand each other: Marburg teams analyze cell communication in epithelial tissues within the Priority Programme SPP 2493.

See further details: www.uni-marburg.de/de/fb20/aktu...

Screenshot of the Node's Jobs Board. Text reads: Welcome to the developmental and stem cell biology jobs board. The board shows only active job adverts – expired adverts will be moved to the jobs archive.

Did you know we have a dedicated Jobs Board?

Whether you're looking for your next job, or you have an open position to advertise, do check out our Jobs Board:
thenode.biologists.com/jobs/

#DevBio #StemCells

Quality of scientific papers questioned as academics ‘overwhelmed’ by the millions published Widespread mockery of AI-generated rat with giant penis in one paper brings problem to public attention

Quality of scientific papers questioned as academics ‘overwhelmed’ by the millions published
Widespread mockery of AI-generated rat with giant penis in one paper brings problem to public attention
@iansample.bsky.social writes @theguardian.com
www.theguardian.com/science/2025...

Everyone is talking about this #paper as if the rat penis is the only weird picture. 😁

I present: Figure 2 and 3/3 😂...

Yep... seems legit to me. JAK interacts with JAK which activates JAK, then JAK and then JA or JK...

All downstream of the proprounization of Stat proteins🤓

#devbio #science