Rianne Lord

Nominations are open until 31st December for this year's Organometallics Distinguished Author Award. Please consider nominating an amazing early career researcher for this award! 🙏🏼🥳

It is always great to be part of the @rsc.org early career events. Thanks again for the invite! 🙏🏼

October has been hectic and I am a little late, but a really warm welcome to our new group members. Eleanore (PhD) working on vanadium metallodrugs, and Andrea and Kulsoom (MChem's) working on iron metallodrugs 🥳👏🏼✨️ Thanks as always to Ben for all your help with them!! 🙏🏼

🎉 We have a BBSRC MIBTP funded PhD open for Oct 2026. Both home and international students are eligible.

💡 This exciting antifungal metallodrug project is in collaboration with Prof. Peter Sadler (Warwick) and Dr Stefan Bidula (UEA)

🖇 warwick.ac.uk/fac/cross_fac/…

‼️application close on 27/11/25

Exciting things to come on antimicrobial resistance research, in our new Stellenbosch-Warwick funded collaboration 🤩🎉🧫
I can't wait to work with South Africa!

Understanding the Modes of Action of β-Ketoiminato Iridium(III) Complexes in Cancer Cells Four new charged iridium(III) 1,2,3,4,5-pentamethylcyclopentadienyl (Cp*) complexes, 1–4, of the type [Cp*Ir(L1–4)(PTA)](PF6) (where L1–4 = functionalized β-ketoiminate ligands and PTA = 1,3,5-triaza-7-phosphaadamantane), have been successfully synthesized and characterized. Single crystal X-ray crystallographic data have been obtained for all compounds and confirm a typical pseudo-octahedral half-sandwich geometry. Cytotoxicity values have been determined against a range of cancerous and noncancerous cell lines and highlight high cytotoxicity and selectivity toward breast cancers. Among these compounds, the unfunctionalized β-ketoiminate Ir(III) complex (1) emerged as the most promising candidate, demonstrating activity that was comparable to or exceeded that of cisplatin, especially after 24 h against the triple-negative MDA-MB-231 cell line. Morphological and molecular analyses confirmed that 1 triggers apoptotic cell death, involving caspase activation and PARP cleavage, which is consistent with its DNA-damaging characteristics, highlighting the future anticancer potential of compound 1.

Late to the party, but...

Congratulations to the group on the latest @pubs.acs.org in Inorganic Chemistry! Thanks for your efforts Tam and Ben 🙏🏼
Thanks also to Dr Ceyda Acilan and her team for the continued collaboration 🙏🏼🎉🥂

pubs.acs.org/doi/10.1021/...

Huge congratulations to my first PhD student Oliver, on passing his PhD with minor revisions! 🎉🥂

Many thanks to Dr Charlotte Willans and Dr Alice Johnson for conducting the viva 🙏🏼

Finally, back to doing what I love.. crystallography. Thanks to my postdoc Ben for these beautiful crystals! 😍💎

We still have a PhD position open in our team.
The deadline is 29th April, and funding is secured for 3.5 years (UK applicants only). Please email me with any queries.
RTs are appreciated! 🙏🏼🙏🏼

Communicating Science OR SEARCH CITATIONS

Please take a look at the ACS information on our Flash Communications and consider Organometallics for communicating rapid reports on initial findings of interest!

More details from our EIC 👇🏼
pubs.acs.org/doi/10.1021/...

Thanks to the @acs.org Organometallics team for the warm welcome/editorial!
pubs.acs.org/doi/full/10.10…

I look forward to receiving all of the bioinorganic papers, so please keep sending them!

We also have our new Flash Communications (details in the comments)

We are happy to announce that a 3.5-year fully funded PhD position is open within our team at the University of Warwick - fees are covered only for home UK students, and the deadline is 29th April 2025.

RTs are appreciated! 🙏🏼

Enquiries: Rianne.Lord@warwick.ac.uk

www.jobs.ac.uk/job/DLQ466/p...

I am delighted to have been asked to be a Topic Editor for @acs.org Organometallics!

I am looking forward to working with the other editors and handling your bioinorganic publications! Also, a plug for more bioinorganic researchers to get submitted!! 🙏🏼🎉