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Korolchuk Lab

@korolchuklab.bsky.social

Cell biology lab at Newcastle University, UK, molecular mechanisms of nutrient sensing and autophagy, ageing and age-related disease πŸ‡ΊπŸ‡¦

2,533 Followers  |  6,048 Following  |  89 Posts  |  Joined: 30.12.2023
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Posts by Korolchuk Lab (@korolchuklab.bsky.social)

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a penguin reading a book with the words happy sunday above ALT: a penguin reading a book with the words happy sunday above

#Autophagy and #mTOR papers from last week, not to be missed!

biomed.news/bims-auttor/...

01.03.2026 11:21 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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a man is sitting on a couch and pointing at something with the word look written on the bottom ALT: a man is sitting on a couch and pointing at something with the word look written on the bottom

#Autophagy and #mTOR papers from last week, don’t miss this selection brought by @biomednews.bsky.social engine!

biomed.news/bims-auttor/...

22.02.2026 10:18 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

New #Autophagy paper from Martens lab:

www.biorxiv.org/content/bior...

18.02.2026 08:45 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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The lysosomal LAMTOR-Rag complex functions as a checkpoint for antiviral interferon production - The EMBO Journal Lysosomes are emerging as important signaling hubs for antiviral defense, yet how they enable type I interferon (IFN-Ξ²) production is unclear. Here, we identify an evolutionarily repurposed lysosomal ...

link.springer.com/article/10.1...

17.02.2026 09:21 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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a cartoon of a girl holding a test tube with the words " it works " on the bottom ALT: a cartoon of a girl holding a test tube with the words " it works " on the bottom

#Autophagy and #mTOR papers from last week, enjoy!

biomed.news/bims-auttor/...

15.02.2026 11:55 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Mitochondrial superoxide regulates nuclear envelope integrity and ageing via redox-mediated lipid metabolism - Nature Metabolism Mitochondrial superoxide production is shown to preserve nuclear envelope integrity by controlling lipid peroxidation, with impact on nuclear and organismal ageing in C. elegans.

A new collection of papers on #Mitochondria in #Health and #Disease! #MitochondrialDisease πŸ“š
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mt superoxide regulates nuclear integrity and ageing via lipid metab

www.nature.com/articles/s42...

08.02.2026 13:06 β€” πŸ‘ 13    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0
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FEBS 2026 | Federation of European Biochemical Societies Congress We are delighted to invite you to the 50th FEBS Congress, which will take place from 4th to 8th July 2026 in Maastricht, the Netherlands. This milestone edition of the FEBS Congress will be hosted by ...

Calling all @biochemsoc.bsky.social members. The #FEBS congress is happening in Maastricht, #Netherlands in July. The abstract deadline is next week and there are bursaries available to support attendance. See you there! #biochemistry

Key deadline: 13 February 2026, 23:59 CET

febscongress.org

06.02.2026 08:12 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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a pigeon is standing next to a pile of dirt and a drain ALT: a pigeon is standing next to a pile of dirt and a drain

Just an idea of working, including sciencing, is making me sick currently. Hopefully just a phase, but is this how all those who hate their jobs but have to work for money feel every day of their adult lives? What a horror 😳

03.02.2026 20:22 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 3    πŸ“Œ 0

A unifying theory of #ageing from colleagues at #NewcastleUni πŸ‘‡πŸΌπŸ‘‡πŸΌπŸ‘‡πŸΌ

Would be interesting to hear your feedback in comments, could this be a new framework for the field of #biogerontology?

www.biorxiv.org/content/10.6...

03.02.2026 09:27 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
bims-proteo 2026-02-01 papers

Good Morning! This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/...
Highlight: CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis www.cell.com/cell/fulltex...

01.02.2026 08:31 β€” πŸ‘ 12    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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a man in a suit and tie is smiling and looking at the camera . ALT: a man in a suit and tie is smiling and looking at the camera .

#Autophagy and #mTOR papers from last week, thanks to @biomednews.bsky.social for running a reliable search engine keeping us up to date with relevant literature. Subscribe to their free services and you won’t regret it!

biomed.news/bims-auttor/...

01.02.2026 09:59 β€” πŸ‘ 14    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
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πŸ“’Last weeks #immunometabolism discoveries @biomednews.bsky.social ⬇️⬇️⬇️

biomed.news/bims-imicid/...

Interesting finding:

Spatiotemporal regulation of energetic charge dictates T cell function @natcomms.nature.com

26.01.2026 14:10 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Good morning everyone, below is last issue of #mitophagy news πŸͺ« πŸ”‹ πŸ—‘οΈ

biomed.news/bims-tofagi/...

This week you'll find insights on the role of mitophagy in germline cells and in inheritance of mtDNA, in mice and in the male arabidopsis germline

Thanks to @biomednews.bsky.social for pre-sorting

26.01.2026 09:00 β€” πŸ‘ 8    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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a cartoon character from blippi is saying let 's go investigate ALT: a cartoon character from blippi is saying let 's go investigate

#Autophagy and #mTOR papers from last two weeks, plenty of interesting stuff and worth looking into:

biomed.news/bims-auttor/...

biomed.news/bims-auttor/...

25.01.2026 10:56 β€” πŸ‘ 8    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
bims-proteo 2026-01-11 papers

Good Sunday Past 2 weeks' selection of articles / #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... and biomed.news/bims-proteo/...
Highlight: Computational design of conformation-biasing mutations to alter protein functions www.science.org/doi/10.1126/...

11.01.2026 07:41 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Good Sunday, all. Here is a great summary of last week's papers in #cancermetabolism and #mitochondrialbiology. Don't miss it! Find it here: biomed.news/bims-camemi/... Biomed News #keepreading

"Life isn't a dress rehearsal; this is it. It's your job to show up for this moment" Oliver Burkeman

11.01.2026 06:37 β€” πŸ‘ 22    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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kermit the frog is dancing in front of a red curtain with the words its week # 2 !!! ALT: kermit the frog is dancing in front of a red curtain with the words its week # 2 !!!

The first two issues of #autophagy and #mTOR papers of the year pre-selected by @biomednews.bsky.social engine. Enjoy and Happy New Year to all!

biomed.news/bims-auttor/...

biomed.news/bims-auttor/...

11.01.2026 12:05 β€” πŸ‘ 13    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Open #postdoc fellowship in my group. Virus replication and cryo-ET. Projects can be tailored to ambitious candidates with diverse backgrounds, so don't hold back from applying! DM for more info.

Deadline 8 Feb. Apply here:
umustipendie.varbi.com/en/what:job/...
#virus #virology #teamtomo #cryoEM

09.01.2026 13:58 β€” πŸ‘ 34    πŸ” 28    πŸ’¬ 2    πŸ“Œ 3
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a happy new year greeting card with a reindeer in a christmas ornament ALT: a happy new year greeting card with a reindeer in a christmas ornament

Happy New Year to all! Let it bring lots of exciting science!

31.12.2025 12:28 β€” πŸ‘ 11    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
bims-proteo 2025-12-28 papers

This week's selection of articles and #preprints on #proteostasisi thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/...
Highlight: Multi-scale classification decodes the complexity of the human E3 ligome www.nature.com/articles/s41...

28.12.2025 11:24 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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a merry christmas card with a christmas tree ALT: a merry christmas card with a christmas tree

The final set of #autophagy and #mTOR papers published this year and preselected by @biomednews.bsky.social engine. Enjoy!

biomed.news/bims-auttor/...

28.12.2025 09:45 β€” πŸ‘ 10    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Happy Sunday!! Here comes a new issue of #cebooc featuring the latest papers in oocyte cell biology!

biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/41419741/

Powered by @biomednews.bsky.social

21.12.2025 08:35 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Good Sunday all. The last weekly issue of papers in #cancermetabolism and #mitochondrialbiology before Christmas is out: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading

I wish you all a great Holiday Season and Merry Christmas to all who celebrate it.

21.12.2025 06:02 β€” πŸ‘ 11    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
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a close up of a pineapple from spongebob squarepants with a hole in it . ALT: a close up of a pineapple from spongebob squarepants with a hole in it .

#Autophagy and #mTOR papers form last week, lots of goodies which shouldn’t be missed, have a peep:

biomed.news/bims-auttor/...

21.12.2025 11:32 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
bims-proteo 2025-12-14 papers

This week's selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/...
Highlight: LRRC59 cooperates with nuclear transporters to restrain the nuclear envelope repair machinery and safeguard genome integrity www.nature.com/articles/s41...

14.12.2025 09:25 β€” πŸ‘ 7    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Good Sunday, all! What a wonderful selection of papers in #cancermetabolism and #mitochondrialbiology. I couldn't stop selecting!! biomed.news/bims-camemi/... Biomed News

"There are three musts that hold us back: I must do well. You must treat me well. And the world must be easy."-Albert Ellis

14.12.2025 06:48 β€” πŸ‘ 17    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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a man in a grey sweater holds his finger up in the air ALT: a man in a grey sweater holds his finger up in the air

#Autophagy and #mTOR papers from last week, with our review on the top, enjoy!

biomed.news/bims-auttor/...

14.12.2025 10:25 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Frontiers | Autophagy–NAD+ axis: emerging insights into neuronal homeostasis and neurodegenerative diseases Autophagy is an evolutionarily conserved catabolic process that plays a central role in maintaining cellular homeostasis by degrading and recycling damaged o...

Great to see our new review on #NAD and #autophagy led by Sovan Sarkar published. Hope it serves as a useful point of reference for the field.

www.frontiersin.org/journals/mol...

13.12.2025 23:11 β€” πŸ‘ 12    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
a pointilllist mito

a pointilllist mito

Good Sunday, all. Don't miss this week's selection of papers in #cancermetabolism and #mitochondrialbiology as there are some true gems: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading

"The everyday human gesture is always a heartbeat away from the miraculous."-Nick Cave

07.12.2025 06:47 β€” πŸ‘ 24    πŸ” 9    πŸ’¬ 1    πŸ“Œ 1
https://www.cell.com/cms/10.1016/j.cell.2025.11.002/asset/6a29b9bb-e6a4-4eb7-a86a-b1f1f5fd697f/main.assets/fx1_lrg.jpg

https://www.cell.com/cms/10.1016/j.cell.2025.11.002/asset/6a29b9bb-e6a4-4eb7-a86a-b1f1f5fd697f/main.assets/fx1_lrg.jpg

Such a great collection of papers on #mitochondrialdisease from #week49! πŸ“š Congratulations to all authors! biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social

Innate immune and metabolic signals induce mitochondria-dependent membrane lysis via mitoxyperiosis
Wang et al

07.12.2025 14:54 β€” πŸ‘ 14    πŸ” 8    πŸ’¬ 1    πŸ“Œ 0