Pascal Albanese

Building the next generation of kick-ass women in marine science, one expedition at a time.
#mesocosm @embl.org

Your sleep pressure is powered by your mitochondria! Sleep, energy, and ageing are all connected through mitochondrial bioenergetics in neurons. Brilliant work from Gero Miesenböck’s lab, just out in Nature @nature.com
www.nature.com/articles/s41...

Science builds bridges🇮🇷🤝🇮🇱
Join me in welcoming our new postdoc Vida who brings PhD in plant sciences and will contribute to new bioenergetic studies. Vida is from Tabriz where her family's lives were disrupted by war. Thankfully no casualties, but career delays to her siblings and psychological toll

Folddisco detects (partial) motifs, allowing for substitutions and angle-length variations, by utilizing an index storing all residue pairs within 20Å encoded as geometric features. For space efficiency, it omits positions and compresses ids through run-length encoding (1.4TB for 53M structures) 2/9

YouTube video by acapellascience The Molecular Shape of You (Ed Sheeran Parody) | A Capella Science

Bluesky needs more music, and the world needs more nerds. This, ladies and gentlemen, is a blast from the past. And a reminder not to underestimate the chemists 😉. #chemsky youtu.be/f8FAJXPBdOg?...

A host organelle integrates stolen chloroplasts for animal photosynthesis Sea slugs steal foreign chloroplasts and store them in specialized organelles that facilitate photosynthesis and eventual digestion to mediate starvation resistance.

Remarkable paper explaining how sea slugs maintain chloroplasts obtained by kleptoplasty active for many month & eventually digest them for resources www.cell.com/cell/fulltex...

Free structural MS hands-on workshop @ BIOCEV (CZ)

📅 Sept 15–19, 2025

For PhDs, postdocs & undergrads (CZ/SK)

HDX-MS, native MS, cross-linking, high-res MS, data processing

Apply by July 31 → bit.ly/3HNyzIg

@spidocs.bsky.social @mbuavcr.bsky.social @ciisbinstructcz.bsky.social

Remember, everything Netanyahu does is to keep himself out of prison. For the sake of one crook's liberty, tens of thousands of people have been murdered, and now a possible full-scale war has been provoked. Israel must rise up and unseat him.

Structure of a stripped-down and tuned-up far-red phycobilisome - Communications Biology CryoEM structure of far-red light adapted allophycocyanin unveils evolutionary adaptations for far-red light photosynthesis and the molecular strategies for efficient light-harvesting under far-red li...

I'm happy to say that our new paper (and the first one out of my PhD thesis) is out!

We describe the CryoEM structure of the phycobilisomes expressed during far-red light photoacclimation, and try to make sense of why these cyano are fond of "minimalism" :)

doi.org/10.1038/s420...

Omaya Dudin Interview with Omaya Dudin, who uses Ichthyosporea as models to study how and why unicellular organisms evolved multicellularity at the University of Geneva.

90% of you probably don’t need to read this.
But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy.
It’s about sharing something hard to say out loud;
partly to heal, partly in case someone needs to hear it too. (1/3)
tinyurl.com/DudinO

Thanks Jim for this Alert. About XL-MS mapping using our tool XMAS: in fig 2C you are plotting the same restraint multiple times (aligned grey dots). To avoid this and show only the shortest in the oligomer you can hit “analyze>find shortest>0Å difference” (default cutoff is 2Å). Cheers :)

Problem cryo-ET structure alert. A recent paper by Lange et al. in @natcellbio.nature.com (tinyurl.com/38s6a4dn) reported an unusual-looking model of the prohibitin complex in situ. We asked: how was this structure generated? Our reanalysis offers an explanation: tinyurl.com/mszdtwxx 🧵

ChlamyAnnotations/chlamydataset2relion5 at master · Chromatin-Structure-Rhythms-Lab/ChlamyAnnotations Particle annotations for the large-scale cryo-ET dataset of Chlamydomonas reinhardtii - Chromatin-Structure-Rhythms-Lab/ChlamyAnnotations

To all #ChlamyDataset enthusiasts, here is a script that lets you directly import the pre-processed results from EMPIAR-11830 into #RELION v5 for subtomogram averaging:

github.com/Chromatin-St...

#Chlamydomonas #TeamTomo #CryoET #OpenSoftwareAcceleratesScience

Structural basis of lipid transfer by a bridge-like lipid-transfer protein - Nature The LPD-3 complex structure reveals protein–lipid interactions that suggest a model for how the native LPD-3 complex mediates bulk lipid transport and provides a foundation for mechanistic studies of ...

"Our LPD-3 complex structural data reveal protein–lipid interactions that suggest a model for how the native LPD-3 complex mediates bulk lipid transport and provides a foundation for mechanistic studies of bridge-like lipid transport proteins (BLTPs)." 🤯🤯😍

www.nature.com/articles/s41...

Zoomed out view of scientists sampling a beach on the TREC expedition

TREC is now on Bluesky! The expedition has gathered samples all along Europe’s coasts – now scientists are exploring what the data tell us. We’ll be sharing insights into this amazing ongoing work! Spread the word! @embl.org @taraoceans-science.bsky.social @embrc-eu.bsky.social 📸Massimo Del Prete

YouTube video by The Royal Institution How the Krebs cycle powers life and death – with Nick Lane

Biochemist Nick Lane on the body electric ⚡ and the cycle that drives all carbon based life-forms on earth 🍃🌍

youtu.be/vBiIDwBOqQA #KrebsCycle #Complexity #Science #Biochemistry #Life 🧬🦠🔬

"Wound wood" is ecological engineering by the Earth Mother at its best! The tree seals the damage, fungi move in, beetles make tunnels, and here, Anolis carolinesis (green anole lizards) use it for a home. Decay signals transformation, not THE END. #WoundWood #Trees #Naturalist #botany #photography

Metabolites are not genes — avoiding the misuse of pathway analysis in metabolomics - Nature Metabolism Pathway analysis, originally developed for gene expression data, has been adapted for metabolomics. However, owing to the unique characteristics and constraints of metabolites compared with genes, pat...

Metabolites are not genes — avoiding the misuse of pathway analysis in metabolomics www.nature.com/articles/s42...

Tissue-like multicellular development triggered by mechanical compression in archaea The advent of clonal multicellularity is a critical evolutionary milestone, seen often in eukaryotes, rarely in bacteria, and only once in archaea. We show that uniaxial compression induces clonal mul...

Pretty much everything is fucked, but here is some beautiful and exciting science from @archaeon-alex.bsky.social and colleagues.

www.science.org/doi/10.1126/...

two men in military uniforms are standing next to each other and one has a badge on his arm that says ' a ' ALT: two men in military uniforms are standing next to each other and one has a badge on his arm that says ' a '

#HeardToday “You can’t solve mechanisms with genomics. For that you need to go to the trenches and do BIOCHEMISTRY!”

The many facets of photosynthesis meeting, 26-28 May, Paris

🌿Join us for the 2025 congress of the French Society of Photosynthesis in Paris May 26–28!

🌱 Exciting sessions on a broad range of topics related to photosynthesis.

📌 Abstract deadline: March 31
✨ Free registration for students & postdocs 😁

👉 mfp2025.sciencesconf.org?lang=en

#Photosynthesis

Who does that? We rented a train JUST for the conference, that will take the participants from Prague to the woods of Bohemia. There'll be talks ON THE TRAIN. In Prague we'll have 5 locations with different atmospheres.
#theconferencetoendallconferences Register now:
woodstock.img.cas.cz

MITOtalks this week

IMBA is recruiting a Junior Group Leader! Are you interested in starting your own lab, pursuing curiosity-driven basic research in the life sciences? Apply now to our group leader position. The deadline is May 28. Link is below.

Structure of an oxygen-induced tubular nanocompartment in Pyrococcus furiosus Reactive oxygen species (ROS) pose a significant threat to biological molecules, prompting organisms to develop systems that buffer oxidative stress and contain iron, which otherwise amplifies ROS pro...

And now to something completely different: the response of an anaerobic archaeon to oxidative stress. Tubular nanocompartments encapsulate virus-like particles! Great work by Wenfei Song and many colleagues from @bijvoet-centre.bsky.social and @mib-wur.bsky.social.
www.biorxiv.org/content/10.1...

When predictions meet experiments: the next challenges in structural biology Building on the success of the 2022 EMBO Workshop “When Predictions Meet Experiments: The Future of Structure Determination”, this second edition continues the journey at the interface of computation…

meetings.embo.org/event/25-str...

The final version of our work on the in-cell architecture of the mitochondrial respiratory chain is now online in @science.org 🎉
You can find the full story here www.science.org/doi/10.1126/...
@verenaresch.bsky.social did a wonderful job on the cover and animation, she really brought it to life 👩‍🎨

Decoding genetic diversity through genome engineering in bryophytes Bryophytes have achieved evolutionary success, spreading widely thanks to their genetic diversity. This review highlights recent advancements, from precise gene editing to synthetic genomics, and emp...

𝐅𝐨𝐜𝐮𝐬𝐞𝐝 𝐫𝐞𝐯𝐢𝐞𝐰📚
Decoding genetic diversity through genome engineering in bryophytes
📖 doi.org/10.1111/tpj....
🖊️ Ye, Luo, Liu, Cao et al
This review explores genome engineering in bryophytes, unlocking advances in agriculture, biotech, and more. 🌿🔬

Makes sense