Nicolas Rivron

Watson was deeply influential to me as a genomicist, but not how you may assume

From stealing Rosalind Franklin's lab notes to his frequent sexist & racist bioessentialist comments later in life, he showed how the scientific community would still worship a terrible person

Don't idolize bad people

Conservation and alteration of mammalian striatal interneurons - Nature An analysis of cell-type diversity in brain samples from a variety of mammalian species, both during development and in adult animals, reveals that the TAC3 initial class of striatal interneurons is c...

Our new manuscript, led by Emily Corrigan, examines inhibitory neuron diversity across approximately 160 million years of evolutionary divergence, as part of BRAIN Initiative Cell Atlas Network (BICAN) developing brain atlas package: www.nature.com/articles/s41...

The ethical framework for embryo models needs clarity and simplicity. The spirit of the integrated/non-integrated distinction was to more prominently regulate models that could potentially develop into a fetus. Hafez Ismaili M’hamdi discusses this. www.progress.org.uk/complexity-w...

Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab!

Thankful for any retweet! 🫶

imba.onlyfy.jobs/job/l6u2m980

Join us in Vienna! The line-up of speakers is ready!

Congratulations to Theresa Sommer on the completion of her PhD! Theresa, a researcher in the Nicolas Rivron Group, presented her work on “Developing a stem cell – based 3D model of the human blastocyst and its application in exploring mammalian embryo morphologies” at her PhD defense.

A genome-wide atlas of human cell morphology - Nature Methods An optical pooled cell profiling platform (PERISCOPE) based on Cell Painting and optical sequencing of molecular barcodes was used to develop the first unbiased genome-wide morphology-based perturbati...

Our paper “A genome-wide atlas of human cell morphology” is finally out today in @naturemethods.bsky.social ! www.nature.com/articles/s41...

(I tweeted about our preprint in 2023 over at the bad place, but deactivated my account, so here we go again!)

1/3 Embryogenesis requires fit cells. Here, following work from @miguel-torres-1963.bsky.social & @tristanrodriguez72.bsky.social and led by @joshifrenster.bsky.social we develop a #gastruloid model of #CellCompetition
www.biorxiv.org/content/10.1...
showing it recapitulates much of the embryo 🧵

The mobile genome: genetic and physiological impacts of transposable elements

Dear all, registrations are open for the Mobile Genome @EMBO workshop. Many slots for posters, short talks but also long talks for last minute groundbreaking results! Let’s meet again on Nov 4-7, 2025 in Heidelberg. www.embl.org/about/info/c...

We are #hiring! Join GMI as the new Operation Engineer and supervise the technical, economic support and maintenance of the buildings. #europe #jobs #science https://imba.onlyfy.jobs/job/2fow0g5m

We are hiring! Join IMBA as the new Operation Engineer and supervise the technical, economic support and maintenance of the buildings. #europe #jobs #science https://imba.onlyfy.jobs/job/2fow0g5m

BMAL1 is a critical regulator of sex-specific gene expression in the heart Pieterjan Dierickx; BMAL1 is a critical regulator of sex-specific gene expression in the heart, Function, , zqaf004, https://doi.org/10.1093/function/zqaf0

Check out our Perspective on a new @kaesser.bsky.social lab study showing that the circadian clock protein BMAL modulates sex-specific differences in both rhythmic and non-rhythmic cardiac gene expression: academic.oup.com/function/adv...
Original paper: academic.oup.com/function/adv...
@dzhk.de

I’m very excited about this collaborative project! We managed to significantly scale up and streamline human blastoid generation without the use of feeders. @leeboratory.bsky.social @grazianomartello.bsky.social @pasquelab.bsky.social and Nicolas Rivron @ucph.bsky.social

With pleasure we share our preprint reporting robust and cost-effective expansion of naive human Pluripotent Stem Cells without feeder cells. A fantastic collaborative effort with @leeboratory.bsky.social @jzylicz.bsky.social @pasquelab.bsky.social and Nicolas Rivron.

tinyurl.com/5n6z9rt9

Feeder-free culture of naive human pluripotent stem cells retaining embryonic, extraembryonic and blastoid generation potential Conventional human pluripotent stem cells (hPSCs) are widely used to study early embryonic development, generate somatic cells, and model diseases, with differentiation potential aligned to a post-imp...

Exciting community effort for robust feeder-free maintenance of human naive pluripotent stem cells with blastoid formation potential. Collaboration with @grazianomartello.bsky.social, @leeboratory.bsky.social @jzylicz.bsky.social @nicolasrivron.bsky.social tinyurl.com/5n6z9rt9

A pleasure for Emiel Van Genderen and myself to be able to contribute to this study that helps build solid foundations for conscientious modeling of human development through robust and efficient protocols. Doing science together with such people is a privilege. Thanks @grazianomartello.bsky.social

We are happy to contribute to this exemplary collaborative study aimed at improving the efficiency of working with human naïve ESCs without MEF feeder cells. With @grazianomartello.bsky.social‬, @jzylicz.bsky.social, @pasquelab.bsky.social, and @nicolasrivron.bsky.social
tinyurl.com/5n6z9rt9

The deadline to submit your abstract for a talk at the 2025 SY-Stem Symposium has been extended to January 22, 2025. Registration deadline remains on February 15th. For more details and to submit your abstract, visit: www.sy-stem.org
We hope to see you there!

#SYStem2025

Join us in Vienna! A symposium dedicated to young scientists doing stem cell research with most talks by First authors in the transition to independent positions!

Scanning electron microscope image of a human trunk-like structure (left) and human embryo (right) false coloured for somites (magenta) and neural tube (gold).

Have you ever wondered how your back formed? The human embryo makes a neural tube (future spinal cord) and somites (trunk muscle/bone) from ~d20. They’re formed at the same time and place, so we used human Trunk-like Structures (hTLS) to investigate their ‘co-development’… (1/7)

Photo of Human Technopole

Thrilled & immensely honoured to receive the Italian Science Fund (FIS) Starting Grant. We will uncover the mechanisms underlying HSV-1 latency and reactivation in human, disease relevant, cells.

Postdoc positions in virology and human stem cell biology @humantechnopole.bsky.social available soon!

The ISSCR invites all students and postdoc members to create their own session at #ISSCR2025! Choose your own topic and showcase recent developments and scientific breakthroughs that you’re passionate about. Learn more 👉 bit.ly/3Op2MxB

I'm speaking at ISSCR 2025 Annual Meeting, join me Register now

Happy New Year! I look forward to the #ISSCR2025 annual meeting in Hong Kong and hope to see you there to talk about how to use #blastoids and all other stem cell based embryo models to make important scientific and medical discoveries! invt.io/1txbejpdn2u
@isscr.org