Krzysztof Kiryluk

Join us for ‘#LUPUS: Current & Future Breakthroughs’ – a virtual and in-person conference on Friday, September 12, 2025 with 7.50 ACCME Credits. Registration & info:
www.eventleaf.com/e/Lupus2025
#lupus #arthritis #Nephritis #CARTcell #autoimmune #autoimmunedisease #rheumatology #MedEd

N.I.H. Workers Denounce Trump’s ‘Harmful’ Health Policies

www.nytimes.com/2025/06/09/h...

Here Are the Nearly 2,500 Medical Research Grants Canceled or Delayed by Trump Some cuts have been starkly visible, but the country’s medical grant-making machinery has also radically transformed outside the public eye.

The Gutting of America’s Medical Research: Here Is Every Canceled or Delayed N.I.H. Grant www.nytimes.com/interactive/...

www.economist.com/leaders/2025...

Uncovering the pathogenesis in glomerulonephritis—

ASCI member Ali G. Gharavi & team discover GALNT14 variants in patients with IgA nephropathy that link O-glycosylation defects with altered mucosal immunity and B cell homing: buff.ly/Q8zdWgy

Trump Has Cut Science Funding to Its Lowest Level in Decades The lag in funding extends far beyond D.E.I. initiatives, affecting almost every area of science: chemistry, computing, engineering, materials and more.

Trump Has Cut Science Funding to Its Lowest Level in Decades www.nytimes.com/interactive/...

This is a disaster on multiple levels. The litany of bad ideas continues to flow freely...

YouTube video by LastWeekTonight RFK Jr. & HHS: Last Week Tonight with John Oliver (HBO)

I am late to this but @lastweektonight.com is doing better journalism on the Trump-induced crisis in American public health than most other "real" mainstream media outlets. Watch it, all of it. #RFKMustGo. youtu.be/8H34jcpEsFs?...

The Editorial in full.

🆕 “Science and medicine in the USA are being violently dismembered while the world watches [...] bullies are only emboldened by acquiescence or indifference.”

The Lancet’s latest Editorial: Supporting medical science in the USA www.thelancet.com/journals/lan...

Hundreds more NSF grants terminated after agency director resigns Sethuraman Panchanathan abruptly leaves helm of US funding agency after Elon Musk’s DOGE arrives.

Fresh turmoil has hit the US National Science Foundation: hundreds more of the agency’s research grants were terminated today on top of the hundreds already terminated last week, Nature has learnt.

https://go.nature.com/3YOHqiq

Posting on behalf of Shamil Sunyaev: Eimear(Vice Chair) and I (Chair) are organizing the 2025 Gordon Research Conference (GRC) on Human Genetics and Genomics, which will be held on July 6-11, 2025 in beautiful University of Southern Maine, Portland, Maine.

“I Am Seeing My Community of Researchers Decimated” Across the country, the Trump Administration’s assault on public institutions and its cuts to government funding are forcing scientists to abandon their work and the patients who benefit from it.

The Trump Administration’s cuts at Health and Human Services hit every part of the scientific establishment: not only the federal government and universities but also states, counties, cities, and the private sector.

Lorundrostat Efficacy and Safety in Patients with Uncontrolled Hypertension | NEJM Aldosterone dysregulation contributes to hypertension. Lorundrostat is an aldosterone synthase inhibitor, but data on its efficacy and safety in patients with hypertension are limited. In this mult...

The ASIs have arrived

www.nejm.org/doi/full/10....

Aldosterone synthase inhibitors - first one to finish the phase 3 line

#Lorundrostat #Hypertension

Harvard Sues Trump Administration Over Threats to Cut Funding Harvard’s lawsuit comes after the administration sought to force the university to comply with a list of demands by cutting billions in federal funding the school receives.

Good for Harvard. Hope Columbia will do the same! www.nytimes.com/2025/04/21/u...

Trump Officials Blame Mistake for Setting Off Confrontation With Harvard An official on the administration’s antisemitism task force told the university that a letter of demands had been sent without authorization.

Another twist to the story, and a shocking display of the administration's utter incompetence: Trump Officials Blame Mistake for Setting Off Confrontation With Harvard www.nytimes.com/2025/04/18/b...

Medical Journals Get Letters From DOJ At least three journals received letters from a U.S. Attorney asking about 'competing viewpoints'

Meanwhile, DOJ lawyers are threatening medical journals for not providing adequate "viewpoint diversity" and for misinforming their readership, which I suppose means not publishing enough of the stupid shit that RFK Jr., JB, etc. keep saying.

This is an outrageous First Amendment violation.

Despicable AND dishonest.

Why Harvard Decided to Challenge Donald Trump Universities are accustomed to acquiescing to the government, but Trump made Harvard an offer it couldn’t not refuse.

Universities, which are defined by academic independence yet depend on government support, are extremely vulnerable to government bullying. Harvard’s decision suggests that some, at least, have a limit to how far they’re willing to be pushed.

Opinion | What Trump Just Cost America Do you think these former close U.S. allies are ever going to trust getting into a trench with this administration again?

Great points and my favorite quote of the day "If you hire clowns, you should expect a circus." What Trump Just Cost America www.nytimes.com/2025/04/09/o...

President Trump offered praise to a white-supremacist rally that included chants of “Jews will not replace us,” publicly dined with Holocaust deniers, made common cause with Germany’s Nazi-descendant AfD party and invoked tropes about wealthy Jews. The true motivation behind his attack on universities is suggested by Vice President JD Vance’s declaration that the “universities are the enemy.” Shakedown is the administration’s strategy as it has gone after law firms, federal judges, legislators who disagree with its edicts and traditionally independent arms of the government. Title VI of the 1964 Civil Rights Act appropriately allows that federal funding of universities can be made contingent on their avoiding discrimination. But as a recent statement by a group of leading law professors points out, it also protects against this power’s being used to punish critics or curtail academic freedom. Among the law’s requirements are notice periods, hearings, remedies that are narrowly tailored to specific infractions and a 30-day congressional notification before any funding is curtailed. None of this appears to be part of the Trump administration’s approach to universities.

Universities facing those threats should make clear they are willing to negotiate with government officials only over matters covered by statute and through the procedures laid out in the law. They should make clear that their formidable financial endowments are not there to simply be envied or admired. Part of their function is to be drawn down in the face of emergencies, and covering federal funding lapses surely counts as one. As a former president of Harvard University, believe me when I say that ways can be found in an emergency to deploy even parts of the endowment that have been earmarked for specific use by their donors. And to maintain the moral high ground, which universities have in large part lost, they need a much more aggressive reform agenda focused on antisemitism, celebrating excellence rather than venerating identity, pursuing truth rather than particular notions of social justice and promoting diversity of perspective as the most important dimension of diversity.

In light of HHS freezing all research funds to Columbia today, I think this op-ed from Larry Summers last week is worth revisiting. Universities should:
- Negotiate only over matters covered by statute
- Leverage endowments
- Implement their own reforms

archive.is/KL3Dd

Nice to see this - hope all other major Universities take the same stance.

Picture of the day.

Trump Administration Cuts Princeton Funding to Study Climate Change The cuts to a Princeton University program come as the Trump administration has been reviewing an array of research grants related to global warming.

I am feeling much less anxious about the climate change already… www.nytimes.com/2025/04/09/c...

NIH freezes all research grants to Columbia University Amid negotiations with Trump, the university could risk losing nearly $700 million

The damage to the medical school and health sciences will be irreversible. NIH freezes all research grants to Columbia University | Science | AAAS www.science.org/content/arti...

Finally, top scientists speak up against the Trump administration in a letter signed by 2,000 elected members of the National Academies of Sciences, Engineering, and Medicine: "the nation's scientific enterprise is being decimated"; see related NYT coverage here:
www.nytimes.com/2025/03/31/s...

Columbia's annual "IgA Nephropathy 2025 Diagnosis & Treatment Updates" CME course coming up on April 4th. Join us for a great day packed with the latest data: complement inhibition, B-cell therapies, SGLT2i, DEARA, and more... @cuimcmedicinedept.bsky.social @columbiakidney.bsky.social

Overseas universities see opportunity in U.S. ‘brain drain’ But many U.S.-based scientists seeking to leave may struggle to find positions in countries grappling with funding issues of their own

Universities around the world have reported seeing an uptick in applications from U.S.-based researchers, who face an increasingly uncertain climate under President Donald Trump’s administration. scim.ag/4ibvP4T

Legal Experts Question Trump’s Authority to Cancel Columbia’s Funding The government has demanded drastic changes to the university before it will consider reinstating $400 million. Lee C. Bollinger, the school’s former president, calls it an “existential threat.”

Finally, a coherent call for a legal action: Legal Experts Question Trump’s Authority to Cancel Columbia’s Funding www.nytimes.com/2025/03/17/n...

Nice to see this in print - combined analysis of #CureGN and #CRIC demonstrates the value of broad family history collection from patients with various forms of CKD. Interestingly, positive family history of diabetes was associated with a higher risk of CKD progression even in non-diabetics!

Brown University Surgeon and Professor Are Deported to Lebanon Despite a Judge’s Order Dr. Rasha Alawieh, a kidney transplant specialist and Brown University professor who had a valid visa, was expelled in apparent defiance of a court order.

Thanks to President Trump, we are finally cleansing our country of … kidney-transplant specialists who “fly through the night to pick up donated organs before performing emergency surgery”

www.nytimes.com/2025/03/16/u...