Clinical & Experimental Immunology

person reading posters at BSI congress

Well done to the recipients of this year’s BSI journals-sponsored Poster Prizes! 🎉

Congrats to Flavio Beke, Aisling Newing & Rébecca Barascud for their brilliant contributions. 👏

Read more: https://bit.ly/3MljD6r

Attending #BSI25? Don't miss 'Immunology in the Balance' at 16:30 today. 🧬⚖️

See our very own Editor-in-chief Claudia Mauri discuss how immunity is regulated to stay effective & safe.

See the programme here: https://bit.ly/4a5iBp1

Attending #BSI25?📣 Don’t miss AI in Publishing with Rachel Moriarty from our publisher OUP.

Explore how AI is shaping journals, research integrity & ethical practice, plus tips for using AI responsibly as an author.

🗓 3 Dec 2025 | ⏰ 13:15–14:10 | 📍 Hall 1C

Attending #BSI25? 📣 Meet our Editor-in-Chief, Claudia Mauri!

Join us at the BSI stand this evening (18:00–19:30) in the exhibition hall to hear more about Immunology and Clinical & Experimental Immunology. Come say hello! 👋

🔬 New in the “Clinical & Experimental Treatment of…” series: residual immune activation persists in people with HIV on ART. This review explores strategies to reduce inflammation and guide future research.

📖 https://bit.ly/4g5VMm4

#HIV #Immunology #ART #WorldAIDSday

Rotavirus vaccines save lives, but CMV exposure may reduce responses in some infants. New research highlights this challenge in HIV-exposed, uninfected babies, underscoring the need for equity in early-life health.

📖 Learn more: https://bit.ly/3DX1oAq

#WorldAIDSDay #Immunology #ChildHealth

🦠 How do gut cells shape infections? This study, part of the Review Series - Organoids to Study Immune Cells Development and Function (Ed. Joana Neves), uses organoids to reveal how pathogens target specific cells!

🔬 Read more: https://bit.ly/422Z96U

#GutHealth #Organoids #InfectiousDiseases

🛡️ This #PublishingIntegrityWeek, BSI journals are tackling papermills, promoting AI transparency, DEI & accessibility, and supporting ethical research in immunology.

Read more 👉 https://bit.ly/4odyvAZ

💙 On #WorldDiabetesDay, explore new insights into immune regulation in childhood #T1D.

An Open Access study in Clinical & Experimental Immunology links Galectin-1 with inflammation & Treg cells in children with type 1 diabetes.

Read more 👉 https://bit.ly/4r3C2Vw

Tomorrow marks #WorldDiabetesDay, check out this Open Access study: a new LIPS assay detects zinc transporter 8 autoantibodies (ZnT8A) quickly, safely, and with minimal blood, helping identify children at risk for type 1 diabetes.

Read more 👉 https://bit.ly/3JBSPhw

🧫 Organoids reveal how gut epithelial diversity shapes host–pathogen interactions, enabling study of viruses, bacteria & parasites previously impossible in vitro.

👉 https://bit.ly/422Z96U

#Organoids #GutImmunology #Immunology

📘 People living with HIV can experience residual immune activation even on ART, raising comorbidity risks.

Krystelle Nganou-Makamdop reviews human studies on anti-inflammatory therapies and future strategies.

👉 https://bit.ly/4g5VMm4

#HIV #Immunology

New study finds IL-17 deficiency may underlie cryptococcosis in HIV-negative “immunocompetent” adults. Could unlock new paths for immunotherapy! 🦠🧬

Open access: https://bit.ly/47rL1Xq

#Immunology #Cryptococcosis #IL17 #InfectiousDiseases

Heading to #BSACI2025? 🫁

We’ve been looking at how allergens ramp up IL-18 & IL-18Rα in Th2/Th17 cells in allergic asthma, and what that means for therapy.

👉 https://bit.ly/4qgknJE

#Allergy #Immunology

Going to #BSACI2025? Let’s talk neutrophils!

🧬 Our new open-access review covers their surprising roles in allergy and potential therapeutic targets.

👉 https://bit.ly/3GReFeX

#Allergy #Immunology

🏆Following last week's #NobelPrize announcement, we've pulled together a new virtual issue.

🔎Check it out for must-read articles on peripheral immune tolerance published in the BSI journals: immunology.org/publications...

HYCO-3, a dual-action CO-releaser/Nrf2 activator, modulates immune cells by reducing pro-inflammatory cytokines & antigen presentation. Promising strategy for autoimmune & chronic inflammatory disorders.

Read more 👉 https://bit.ly/3Gf7UDk

#Immunology #Autoimmunity

Neuro-Behçet’s disease is a rare but severe manifestation of Behçet’s. This review highlights advances in diagnosis, biomarkers (IL-6, autoantibodies, BAFF), and immunopathogenesis.

🔗 https://bit.ly/4gZDyU0

🩺 New review highlights immunological insights in liver transplantation from host–graft responses to biomarkers predicting rejection, emphasizing the quest for operational tolerance.

🔗 https://bit.ly/46xnt4l

#LiverTransplant #Immunology

🔬 New study shows 2B4 (CD244) binds Staphylococcus aureus exotoxin SEB, driving allergic inflammation.

2B4 knockout mice had reduced inflammation → a potential therapeutic target.

Read here: https://bit.ly/4my2B1e

#Immunology #Staphylococcus #Inflammation

🦴 New study identifies CFI, an NKT cell–related gene, as a promising biomarker in osteoarthritis.

Validated in patients & mouse models, CFI knockdown reduced inflammation.

🔗 https://bit.ly/42Lz1OT

#Osteoarthritis #Biomarkers #Immunology

Persistent immune activation remains a challenge for people living with #HIV, even with viral control.

On #HIVandAgeing Awareness Day, discover strategies to improve long-term immune health

Read the study here👉 https://bit.ly/4g5VMm4

A novel Fc-modified anti-haptoglobin mAb shows non-inferior efficacy to IVIG in an ITP monkey model at much lower doses, potentially reducing treatment burden.

Open Access 👉 https://bit.ly/4mN8dWJ

#Immunology #ITP #MonoclonalAntibodies

Attending the UK inflammation 2025 meeting? #BSIInflammation2025

If your research explores innate immunity & inflammation, consider submitting to Clinical & Experimental Immunology, showcase your work to a global audience!

Learn more🔗 https://bit.ly/443pf8s

Heading to the UK Inflammation 2025 meeting? #BSIInflammation2025

Check out how sulforaphane targets NLRP3 inflammasomes to relieve inflammation in CP/CPPS, preclinical insights that could inform future therapies.

Read the full study🔗 https://bit.ly/45QNNpI

HTNV infection impacts CD8+ MAIT cells in HFRS patients, causing both activation and depletion.

These cells show antiviral properties, highlighting a key role in disease defence.

Open Access 👉 https://bit.ly/4g4SoYA

#HFRS #Immunology

CD56 on immune and tumor cells: what is the known and beyond? @ceijournal.bsky.social
academic.oup.com/cei/advance-...

🧠 Altered B-cell subsets and cytokine expression are linked to disease activity in CIDP.

Findings suggest immune signatures could help guide diagnosis and prognosis.

🔗 https://bit.ly/3rzemhN

#CIDP #Neuroimmunology

Alzheimer’s disease is one of the greatest health challenges of our time.

This #WorldAlzheimersMonth, Clinical & Experimental Immunology calls on immunologists investigating Alzheimer’s & immunity to share their findings with us.

Submit here: https://bit.ly/443pf8s

@alzheimerssoc.bsky.social‬

💉🌐 Oral vaccines are cheap, easy & life-saving, but why do they underperform in the places they’re needed most?

This paper highlights multifactorial causes & urges tailored solutions for equity in immunisation.

👉 https://bit.ly/42aACy3

#ImmunisationAwarenessMonth