ALS Therapy Development Institute

Finding ALS trials shouldn’t be overwhelming.

The updated ALS Trial Navigator now features:
✔ Simplified experience
✔ Provider Quick Start
✔ NEALS-affiliated filter

Learn more:
als.net/news/the-als...

Today is National Caregivers Day.

To the extraordinary caregivers in the ALS community, thank you. Your strength and resilience fuel our urgency and push our research forward.

We see you. We honor you.

Champion Insights is open. The enrollment portal is live at championinsights.org.

At-home ALS research for high-risk/high-performance populations (endurance athletes, military, and first responders).

If you know someone who is eligible, please share.

#ALS #endALS

We’re excited to share that NEALS is partnering with ALS TDI on the ALS Trial Navigator.

People searching for clinical trials through NEALS can now use the ALS Trial Navigator on the ALS TDI website.

More updates coming in February!

Science can be powerful—and breathtaking. Congrats to Swetha Gurumurthy, Associate Scientist II, named runner-up in the Royal Society Publishing Photography Competition for her image of iPSC-derived motor neurons studying ALS.

Read more here: als.net/news/als-tdi...

🏀 Game on for a cause! This February, Hoops 4 ALS is bringing the heat with 4 Games you won’t want to miss.

Tune in or join us in person to cheer on the teams and help support ALS research. Let’s make every point count!

We’re excited to share that NEALS is partnering with ALS TDI on the ALS Trial Navigator.

People searching for clinical trials through NEALS can now use the ALS Trial Navigator on the ALS TDI website.

More updates coming in February!

You rode. You ran. You danced. You sold. You played. You hosted. You even raised a glass!

And together, events hosted by YOU raised $3.5 million for ALS research at ALS TDI in 2025.

We are endlessly grateful—and can’t wait to see where 2026 takes us. 💜

Beat the cold in style ❄️

Our new 'END ALS' winter beanies are here! Be sure to grab one while they last and help fuel ALS research.

Get yours today: alstdi.88blue.com

What started as a family love of running became a mission to #EndALS.

Connor McCullum ran the 2025 NYC Marathon for his dad after an ALS diagnosis—raising nearly $17K for research along the way.

Read the full story: als.net/news/connor-...

As we enter a new year, it’s time to take stock—not celebrate. Progress in ALS research happens quietly, over time, because people invest before certainty. In 2026, ALS TDI is focused on growth, acceleration, and urgency with rigor. Read more → als.net/news/on-prog...

AP-101 just advanced toward Phase 3 trials—and ALS TDI helped make it possible.
Years ago, donor support funded the unglamorous preclinical work behind this moment.
That’s the power of flexible research funding.

Read more: www.als.net/news/a-story...

What does it mean to be a nonprofit biotech?

At ALS TDI, it means inventing and advancing new medicines in our own lab—accountable only to the ALS community. Every dollar goes back into urgent, open ALS research. Your support fuels the science.

Donate: als.net/endals2025/?...

Happy holidays from all of us at ALS TDI. We’re deeply grateful for our community of supporters, scientists, and advocates who make our work possible. Wishing you a season filled with comfort, connection, and time with those you love.

LIMITED BIBS LEFT! Run for ALS research in:

🇫🇷 Hoka Semi de Paris
🇫🇷 Schneider Electric Marathon de Paris
🇦🇺 TCS Sydney Marathon

Apply NOW to join Team ALS TDI and make every mile count! als.net/news/2026-ma...

Emily is feeling inspired after an energizing four days at the 2025 Alliance Meeting & Allied Professionals Forum in San Diego, CA!

ARC’s in-home blood collection program is powering ALS discoveries — from genomics to biomarker research to global data sharing. 🧬

See how each blood draw accelerates progress at ALS TDI and beyond. Read the full blog: als.net/news/how-blo...

Every discovery brings us one step closer to treatments, and ultimately, an end to ALS. Our team is dedicated to understanding what causes ALS, so no one faces this disease without answers.

Team ALS TDI applications are OPEN for two new 2026 race opportunities! 🏃‍♂️💙

🇺🇸 United Airlines NYC Half — Mar 15, 2026
Apply: fundraise.als.net/marathon/nyc...

🇦🇺 TCS Sydney Marathon — Aug 30, 2026
Apply: sm26.grassrootz.com/the-als-ther...

🔔 Deadline: Dec 5, 2025

The Yozwiak family continues Chris’s legacy with relentless love and action. 💜 Support their mission to help end ALS and fund life-saving research: als.net/news/EOY-202...

Our 2025 Tribute Wall stands as a powerful reminder of the incredible community we are fighting for.

If you’d like to honor someone on our Tribute Wall, you can make a contribution of any size: als.net/2025-tribute.... Thank you for supporting our mission.

Science is taking over our lab! 🧪 Help us make room for research, use code GIVETHANKS25 for 25% off remaining merch while supplies last. We’re moving to a new online store soon, so grab your favorites before they’re gone: fundraise.als.net/store

Compassion drives our work at ALS TDI. Danielle Boyce, our Principal Investigator of Real World Evidence, embodies that; advancing rigorous ALS research while honoring the people behind the data. Thank you, Danielle, for your impact and leadership!

🚨 Applications to run with Team ALS TDI in Paris & Big Sur close TODAY, Nov 10! Join us, run in amazing marathons, and help #ENDALS.

Learn more and apply today: als.net/news/2026-ma...

At the 2025 ALS TDI Summit, our CEO and CSO Dr. Fernando Vieira opened with a powerful message on breakthroughs in ALS research and hope for the future.

Watch his talk, and all Summit presentations, anytime at youtube.com/ALSTDI.

💜 November is National Family Caregivers Month, a time to honor those who give so much of themselves to care for others. At ALS TDI, we recognize the vital role caregivers play in every ALS journey. We see you, we appreciate you, and we thank you for your love and dedication.

Thank you to everyone who joined us at our Open House in Watertown! 💙 We loved showing you our lab, reconnecting with the community, and sharing some Ales for ALS brews 🍻

Check out all the photos here: facebook.com/share/p/1CcB...

Thank you to everyone who joined us for our 14th Annual White Coat Affair Gala last Saturday in Boston! 💜

We were so honored to spend an evening full of smiles, dancing, and community with you. Stay tuned for the full photo album from the night! ✨

Thank you to everyone who joined us for the 2025 ALS TDI Summit! 💡 We loved sharing updates on ALS research with you.

What’s one thing you learned? 👇

📸 Livestream recording, photo album & survey coming soon!

Run for something bigger! 🌍💙 Join Team ALS TDI in 2026 for iconic races in Paris, Boston & Big Sur — every mile helps end ALS. 🏃‍♀️💪

Apply by Nov 7, 2025 👉 als.net/news/2026-ma...