Sophia Zebell's Avatar

Sophia Zebell

@sophiazebell.bsky.social

Plant gene regulation and quantitative traits, Previously: RPCV Jamaica πŸ‡―πŸ‡² NIGMS K99 Postdoc in Lippman Lab at CSHL πŸ… Plant Phys AFE 🌱 PhD in Dong Lab at Duke 🌼 she/her

1,050 Followers  |  980 Following  |  14 Posts  |  Joined: 28.11.2023  |  2.0713

Latest posts by sophiazebell.bsky.social on Bluesky

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USDA funding delays under Trump compromise agricultural research Sharp drop in grant awards leaves researchers frustrated

"With 2 weeks left before the end of this fiscal year, USDA’s [NIFA] had awarded just 558 competitive grants ... 68% fewer than during the prior fiscal yearβ€”and $741 million less in competitively awarded research funds"

Don't forget #PlantSci and ag research, folks.
www.science.org/content/arti...

18.09.2025 14:43 β€” πŸ‘ 49    πŸ” 38    πŸ’¬ 0    πŸ“Œ 0
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Genetic variation at transcription factor binding sites largely explains phenotypic heritability in maize - Nature Genetics Pan-cistrome of the maize leaf under well-watered and drought conditions profiled by haplotype-specific MOA-seq highlights the relevance of transcription factor binding QTLs for understanding phenotypic diversity in maize.

A paper published in Nature Genetics presents a comprehensive pan-cistrome of maize leaves, revealing over 200,000 variants linked to transcription factor binding sites under both well-watered and drought conditions. go.nature.com/4785q5p πŸ§ͺ🌾#plantscience

24.08.2025 14:30 β€” πŸ‘ 24    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0

What a relevant justification! I can't wait to read the resulting issue!

21.08.2025 01:20 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks for posting! I haven't seen your blog before and I really enjoyed the bountiful footnotes and citations!

29.06.2025 15:43 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 2

Other authors, if you can find their contact information online. I know my inbox is less cluttered than senior folks and I try to respond promptly to requests!

12.06.2025 12:07 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

An enjoyable read, with clear simple experiments that show tomato conservation of a core developmental mechanism previously demonstrated in Arabidopsis.

24.05.2025 19:47 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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A wheat tandem kinase activates an NLR to trigger immunity The role of nucleotide-binding leucine-rich repeat (NLR) receptors in plant immunity is well studied, but the function of a class of tandem kinases (TKs) that confer disease resistance in wheat and ba...

2 papers in @science.org this week uncover wheat tandem kinase function. Working in parallel, the authors of each paper show that two different tandem kinases converge to activate the same NLR!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...

#PlantScience

30.03.2025 15:18 β€” πŸ‘ 53    πŸ” 21    πŸ’¬ 1    πŸ“Œ 0

This paper is a tour de force from many friends and collaborators across Solanum expertise! Check it out to learn about the behavior of paralogs in genomes plus the Solanum genus and it's incredible potential for new crops! #plantscienceresearch

05.03.2025 21:46 β€” πŸ‘ 11    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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U.S. gene banks, key to new crops, hobbled by Trump job cuts Newly appointed head of USDA’s genetic repositories axed along with key staff

www.science.org/content/arti...

26.02.2025 13:03 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

This team and our unique dataset have been instrumental in shaping my thinking about paralogs, epistasis, and quantitative genetics. I hope our work inspires others to reconsider the role of genomes in producing the diverse phenotypes of the natural world! #plantscienceresearch

25.02.2025 20:51 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Cryptic variation fuels plant phenotypic change through hierarchical epistasis Cryptic genetic variants exert minimal or no phenotypic effects alone but have long been hypothesized to form a vast, hidden reservoir of genetic diversity that drives trait evolvability through epist...

Thrilled to share our latest preprint, an interdisciplinary look at epistasis between variants in the coding and noncoding genome! #plantscienceresearch www.biorxiv.org/content/10.1...

25.02.2025 20:45 β€” πŸ‘ 15    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Nice work on evolution of genetic interaction between cis-reg elements in floral development! This study really hammered home for me the vast aesthetic difference between having one fewer petal (hideous) and one extra petal (charming) in brassicas. www.pnas.org/doi/10.1073/... #plantscienceresearch

19.02.2025 14:11 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
To My Fellow Lab Rats: A Letter From a Postdoc Who Survived the Bolsonaro Years

β€œYour work is your rebellion” πŸ’ͺ

www.reddit.com/r/labrats/co...

11.02.2025 01:48 β€” πŸ‘ 236    πŸ” 103    πŸ’¬ 4    πŸ“Œ 8

Strong genetics and such a cool example of the consequences of altered TF-DNA binding in domestication!

03.01.2025 13:55 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

Thanks for sharing! I enjoy the concept of "permitting yourself the feeling of doneness".

31.12.2024 15:09 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Diagram illustrating the 4 stages in DNA-free base editing: (1) in vitro transcription, (2) protoplast transfection, (3) protoplast regeneration, and (4) base-edited plants.

Diagram illustrating the 4 stages in DNA-free base editing: (1) in vitro transcription, (2) protoplast transfection, (3) protoplast regeneration, and (4) base-edited plants.

This remarkable new RNA-based adenine and cytosine #BaseEditing system achieves targeted and efficient A-to-G and C-to-T conversions in lettuce, with potential applications in #crop breeding and #PlantBiotechnology.
doi.org/10.1111/jipb...
#PlantScience

31.12.2024 14:28 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Associate Professor / Professor of Evolutionary Genomics - Job Opportunities - University of Cambridge Associate Professor / Professor of Evolutionary Genomics in the Department of Genetics at the University of Cambridge.

Associate Professor / Professor of Evolutionary Genomics
www.jobs.cam.ac.uk/job/49389/

29.11.2024 11:19 β€” πŸ‘ 67    πŸ” 76    πŸ’¬ 2    πŸ“Œ 1
Lehigh University, Department of Biological Sciences Full service online faculty recruitment and application management system for academic institutions worldwide. We offer unique solutions tailored for academic communities.

Calling all #genomics researchers! The small, diverse, friendly Dept of Biological Sciences at Lehigh has a #tenuretrack position: bit.ly/3CYRb5B. App review starts 12/2 (not a hard cutoff). Please join our awesome team!

27.11.2024 22:20 β€” πŸ‘ 24    πŸ” 29    πŸ’¬ 0    πŸ“Œ 0
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Assistant Professor, Integrative Plant Biology - Orlando, Florida, United States The OpportunityThe Department of Biology in the College of Sciences (COS) at the University of Central Florida (UCF) invites applications for a 9-month, tenure track assistant professor, anticipated t...

🚨TT job alert 🚨
Asst. Prof. of Plant Biology @ucf.bsky.social
Deadline: Jan 16 2025

25.11.2024 18:15 β€” πŸ‘ 5    πŸ” 11    πŸ’¬ 0    πŸ“Œ 1
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Starter packs BIOLOGY Ecology Macroecology https://go.bsky.app/GBn9pNZ Global ecology https://go.bsky.app/V6tN4cv Trait based ecology and evolution https://go.bsky.app/PThMXeX Invasion biology https://go.b...

hey everyone! i made a list of some useful starter packs (primarily biology/earth sciences with a few bonus things thrown in) to share with friends who have joined bsky in the last week and thought it may be useful for some people here too! 🌍πŸ§ͺ #SciSky #BioSky docs.google.com/document/d/1...

11.11.2024 17:41 β€” πŸ‘ 730    πŸ” 388    πŸ’¬ 77    πŸ“Œ 38

Sometimes it's just about the right moment for the idea. I know that doesn't fit with the urgent need to secure funding, but if you can hold out and try again I bet your ideas will find their time to shine. I find your love for development inspiring!

19.11.2024 21:09 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Antagonizing cis-regulatory elements of a conserved flowering gene mediate developmental robustness Developmental transitions require precise temporal and spatial control of gene expression. In plants, such regulation is critical for flower formation, which involves the progressive differentiation o...

Putting my postdoc hat back on for a moment to share this beautiful work by Amy Lanctot! She demonstrates both activation and repression within a tomato CRE and shows a different regulatory landscape in Arabidopsis, all with amazing flowering phenotypes! www.biorxiv.org/content/10.1...

05.11.2024 22:01 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Convergent evolution of plant prickles by repeated gene co-option over deep time An enduring question in evolutionary biology concerns the degree to which episodes of convergent trait evolution depend on the same genetic programs, particularly over long timescales. In this work, w...

Phenomenal study from the Lippman lab on convergent evolution: a single gene is responsible for the loss of an important defense trait in many species, from monocots to dicots!
#PlantScience
www.science.org/doi/10.1126/...

02.08.2024 10:02 β€” πŸ‘ 32    πŸ” 17    πŸ’¬ 1    πŸ“Œ 0
Plant Physiology. Calll for Assistant Features Editors. 
Deadline for applications: October 15, 2024.

Plant Physiology. Calll for Assistant Features Editors. Deadline for applications: October 15, 2024.

We're looking for two cohorts of Plant Physiology Assistant Features Editors to start in 2025 and 2026!
See the editorial. Advanced PhD students & postdocs.
I'd be delighted to tell you more in person, at #PlantBio2024, #ICAR2024SanDiego, or #BT2024DBG.
Or message me!
doi.org/10.1093/plph...

13.06.2024 13:49 β€” πŸ‘ 4    πŸ” 12    πŸ’¬ 0    πŸ“Œ 0

Part of this manuscript actually used herbaria to examine evolution of prickles loss across the spiny Solanum... How cool is that!

23.02.2024 13:23 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Pictures of prickles (sharp projections) on various plants: Rosa, Senegalia greggii, Ceiba Speciosa, Bixa orellana, Datura stramonium, Solanum pyracanthos, Aralia spinosa, Smilax, Astrocaryum alatum, Victoria amazonica, Ceratozamia mexicana, and Alsophila firma

Pictures of prickles (sharp projections) on various plants: Rosa, Senegalia greggii, Ceiba Speciosa, Bixa orellana, Datura stramonium, Solanum pyracanthos, Aralia spinosa, Smilax, Astrocaryum alatum, Victoria amazonica, Ceratozamia mexicana, and Alsophila firma

Intrigued by the proliferation of prickly plants across lineages? Jack Satterlee and a triumph of collaborators have answers about convergent evolution of these sharp projections, and how to get rid of them! www.biorxiv.org/content/10.1...

22.02.2024 19:29 β€” πŸ‘ 6    πŸ” 6    πŸ’¬ 1    πŸ“Œ 1
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Extreme restructuring of cis-regulatory regions controlling a deeply conserved plant stem cell regul... bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Proud to have played a small role in Dani Ciren's PhD work, out last week on BioRxiv! Check it out to learn about regulatory sequence rearrangement during evolution! www.biorxiv.org/content/10.1...

02.01.2024 18:47 β€” πŸ‘ 11    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Development has announced the next call for applications for the 'Pathway to Independence' programme - aimed at supporting postdocs going on the job market. Application deadline 31 January 2024.

Full details can be found at journals.biologists.com/dev/pages/pi...

12.12.2023 15:57 β€” πŸ‘ 17    πŸ” 27    πŸ’¬ 0    πŸ“Œ 2

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