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Vizgen

@vizgen.bsky.social

Confidently take your research to new depths with MERSCOPE Ultra integrating single-cell and spatial multiomics analysis powered by MERFISH technology.

344 Followers  |  9 Following  |  89 Posts  |  Joined: 20.11.2024  |  1.4865

Latest posts by vizgen.bsky.social on Bluesky


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We’re proud to support the spatial and single-cell community at #AGBT26!

Vizgen will be in Orlando (Feb 23–26) as a Contributing Sponsor, sharing the latest advances across MERFISH 2.0™, MERSCOPE Ultra™, and integrated transcriptomic + proteomic workflows.

See you there!

13.02.2026 14:18 — 👍 0    🔁 0    💬 0    📌 0

It’s always exciting to see spatial transcriptomics applied beyond traditional biomedical research.

Great work from one of our Certified Service Providers, @earlhaminst.bsky.social‬!

27.01.2026 15:05 — 👍 0    🔁 2    💬 0    📌 0
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Explore the new Vizgen website.

Discover workflows and tools for spatial transcriptomics, spatial proteomics, and integrated RNA and protein analysis in intact tissue.

hubs.ly/Q03_DD9Q0

#SpatialMultiomics

22.01.2026 23:00 — 👍 0    🔁 0    💬 0    📌 0
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Lymphoid gene expression supports neuroprotective microglia function - Nature PU.1low CD28-expressing microglia may act as suppressive cells in Alzheimer’s disease, mitigating its progression by reducing neuroinflammation and amyloid plaque load, indicating potential immunother...

Spatial transcriptomics reveals that microglia play more nuanced roles in Alzheimer’s disease.

A new @nature.com study identifies a PU.1-low, lymphoid-like microglial state near amyloid plaques, linked to reduced pathology.

hubs.ly/Q03-thJp0

21.01.2026 22:59 — 👍 1    🔁 0    💬 0    📌 0
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Great recap from Stanford’s Beckman Center on the recent MERSCOPE User Group Meeting. A nice look at how researchers are applying spatial transcriptomics across brain development, disease, and aging while keeping tissue context intact.

hubs.ly/Q03-sXW30

#SpatialBiology

14.01.2026 18:59 — 👍 0    🔁 0    💬 0    📌 0
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MERFISH is helping reveal how immune cells interact with glia in aging white matter.

In this webinar clip, the Groh Lab shows MERFISH-detected T cells forming distinct niches enriched for CXCL10, primarily from reactive astrocytes.

Full webinar: hubs.ly/Q03Z0mgP0

06.01.2026 00:11 — 👍 0    🔁 0    💬 0    📌 0
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MERFISH is helping reveal how immune cells interact with glia in aging white matter. In this webinar clip, the Groh Lab shows MERFISH-detected T cells forming distinct niches enriched for CXCL10, primarily from reactive astrocytes.

Full webinar: hubs.ly/Q03Z0mgP0

29.12.2025 15:48 — 👍 0    🔁 0    💬 0    📌 0
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We’re excited to announce the winners of the Human Cell Atlasing Grant Program! Each winner will receive one free MERSCOPE Ultra™ slide run using a MERFISH 2.0™ gene panel. Congrats to the winners! We can’t wait to follow your progress. #CellAtlas

24.12.2025 19:17 — 👍 1    🔁 0    💬 0    📌 0
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At a time when the world faces immense challenges, science remains a powerful source of hope and progress.

Meet Vizgen's Kagimoto-san, who helps bring technologies to scientists, strengthening a global community committed to improving lives through innovation.

#BoundByScience

17.12.2025 20:45 — 👍 1    🔁 0    💬 0    📌 0
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What if MS progression is driven by a tiny inflammatory rim at the lesion edge, not diffuse inflammation?

A new Immunity study used MERFISH on Vizgen’s MERSCOPE Platform to map active lesions and uncover this inflammatory niche.

t.co/Q1ATxCzyz2

#SpatialBiology

12.12.2025 20:49 — 👍 2    🔁 0    💬 0    📌 0
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At Vizgen, we are incredibly proud of our worldwide team and the mission that binds us together.

No matter where we live, we are all bound by science, and united by what it makes possible. Meet Anjana from Melbourne, Australia.

#BoundByScience #SpatialGenomics #ScienceforGood

02.12.2025 20:25 — 👍 0    🔁 0    💬 0    📌 0
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SITC 2025: Cancer-Immune Study with Vizgen Learn about investigating cancer and immune cell interactions in the tumor microenvironment with Vizgen's Multi-omics Platforms. Download Vizgen's SITC 2025 posters today!

Miss our posters at #SITC2025?

Now available: Vizgen's poster presentations showing how spatial multi-omics deepens our understanding of the tumor microenvironment w/ MERFISH 2.0™, the MERSCOPE® platform, and InSituPlex® mIF workflows.

Download here: info.vizgen.com/sitc-2025-ca...

26.11.2025 20:20 — 👍 0    🔁 0    💬 0    📌 0
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New Study in Nature | Vizgen The spatial transcriptomics described in this study was enabled by Vizgen’s MERSCOPE® Platform and MERFISH™ chemistry.

Read our latest blog to see how spatial multi-omics is helping researchers move from descriptive anatomy to mechanistic insight in neurodevelopmental disorders. (3/3)

vizgen.com/the-neurodev...

#Neuroscience #DownSyndrome

21.11.2025 20:05 — 👍 0    🔁 0    💬 0    📌 0

Using imaging-based spatial transcriptomics w/MERFISH on >240,000 cells in the mouse brain, enabled on MERSCOPE®, the team identified trisomy-associated gene expression programs in neurogenesis and gliogenesis that underlie altered cortical development in Down syndrome. (2/3)

21.11.2025 20:05 — 👍 0    🔁 0    💬 1    📌 0

New in @nature.com, researchers combined single-nucleus RNA sequencing, high-resolution #spatialtranscriptomics, and proteomics to map the molecular architecture of mid-gestational prenatal Down syndrome cortex and a trisomic Ts65Dn mouse model. (1/3)

21.11.2025 20:05 — 👍 0    🔁 0    💬 1    📌 0
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Just published in Cell Press: Researchers used MERSCOPE® to show how microglia and astrocytes coordinate synapse remodeling in the intact mouse brain, revealing a spatially orchestrated glial dialogue that fine-tunes neural circuits. hubs.ly/Q03SdHXN0

19.11.2025 20:06 — 👍 1    🔁 0    💬 0    📌 0
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Join us at #SfN25 to explore how high-sensitivity #spatialtranscriptomics is reshaping brain research.

Stop by booth 513 and our 2 poster sessions to see how MERFISH 2.0™ and MERSCOPE Ultra™ support deeper, more precise insights into the complexity of the brain.

12.11.2025 22:25 — 👍 1    🔁 0    💬 0    📌 0
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Today at #SITC2025:

Get a first look at how MERFISH 2.0™ data generated on MERSCOPE Ultra™ is combined with InSituPlex® multiplex immunofluorescence on sequential sections to decode the tumor–immune microenvironment.

12:15-1:45 p.m. & 5:35-7 p.m.

#SpatialBiology #SpatialMultiOmics

07.11.2025 16:05 — 👍 0    🔁 0    💬 0    📌 0
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Choosing a spatial platform isn’t just about the next run. It sets you up for your next few years.

See the whole picture and pressure-test your options with our Buyer’s Checklist: hubs.ly/Q03QRXVC0

30.10.2025 21:23 — 👍 0    🔁 0    💬 0    📌 0
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Reminder: Join us 10/30 for the Labroots webinar: From Myelin Damage to Immune Dysfunction: Unravelling the Aging Brain

Updated times: 6 am PDT | 9 am EDT | 2 pm CET | 10 pm SGT

Register: www.labroots.com/ms/webinar/m...

#SpatialTranscriptomics #Neurobiology #SpatialBiology

29.10.2025 13:53 — 👍 0    🔁 0    💬 0    📌 0
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Exploring Biology in Three Dimensions Spatial biology technologies reveal new dimensions for understanding cellular interactions in their native environment.

Spatial biology in 3D. In Genetic Engineering and Biotechnology News, read how combining spatial transcriptomics & multiplex proteomics clarifies tumor–immune signaling & bridges mechanistic insight into clinical readouts. Vizgen’s Manisha Ray weighs in on what’s next for analysis:
hubs.ly/Q03PPC210

24.10.2025 16:10 — 👍 3    🔁 0    💬 0    📌 0
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From Myelin Damage to Immune Dysfunction: Unraveling the Aging Brain Aging is associated with progressive white matter degeneration, which impairs brain structure and function. Defects in myelinating glial cells, combined with chronic neuroinflammation, contr

Join us 10/30 for a Labroots webinar with Dr. Janos Groh: From Myelin Damage to Immune Dysfunction: Unravelling the Aging Brain. Hear how single-cell + spatial transcriptomics reveal glial–immune interactions driving neurodegeneration.

Register: hubs.ly/Q03N0rVJ0

20.10.2025 23:31 — 👍 1    🔁 1    💬 0    📌 0
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Vizgen’s new Cell Atlasing Grant Program is now open.

Top 5 tissue types receive one free MERSCOPE Ultra™ slide run using MERFISH 2.0™. Choose custom 960-gene or 815-gene pre-designed panels (IO, Brain, Breast).

Apply by 10/24. HCA members only. hubs.ly/Q03NCPPv0

16.10.2025 16:05 — 👍 0    🔁 0    💬 0    📌 0
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MERFISH 2.0™ delivers a substantial increase in sensitivity, enabling detection of up to 10× more transcripts per field of view.

Discover how MERFISH 2.0 is transforming spatial biology for researchers like Dr. Bourdenx: hubs.ly/Q03LCNrY0 #SpatialBiology

01.10.2025 21:01 — 👍 0    🔁 0    💬 0    📌 0
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New data release highlights the power of MERSCOPE Ultra to capture high-resolution #spatialtranscriptomics across a 3.0 cm² imaging area:

• Mouse embryo tissue (E10, E12, and E14) on same slide
• Normal and Alzheimer’s human brain on same slide

hubs.ly/Q03KH7VN0

26.09.2025 15:56 — 👍 2    🔁 0    💬 0    📌 0
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Next-gen spatial transcriptomic tools are helping overcome the challenge of degraded & FFPE samples.

Vizgen co-founder Jiang He explains how these advances are opening new doors for research in oncology, neuroscience & beyond:
www.biocompare.com/Editorial-Ar...

18.09.2025 13:17 — 👍 1    🔁 1    💬 0    📌 0
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Just published in Nature: U Mass Chan Medical School, a Vizgen Certified Service Provider, mapped the brain’s molecular landscape across the human lifespan using MERSCOPE®, single-cell RNA-seq & genomic data.

Read: hubs.ly/Q03JsW0z0

#SpatialBiology #Neuroscience #AgingResearch

16.09.2025 16:46 — 👍 1    🔁 0    💬 0    📌 0
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From discovery to clinical research, #SpatialBiology is shaping precision medicine. With Vizgen, researchers now access:

➡️MERFISH 2.0™ spatial transcriptomics
➡️InSituPlex® multiplex protein analysis
➡️STARVUE™ AI image analysis

Explore our tech: hubs.ly/Q03GPSL70

09.09.2025 19:12 — 👍 1    🔁 0    💬 0    📌 0
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How do disseminated tumor cells reveal themselves in the bone marrow?

Using MERFISH 2.0™, Mark Watson, Ph.D.'s team can map 200K–500K cells from bone marrow aspirates and distinguish DTCs from other populations w/ a 140-gene panel.

Full webinar: hubs.ly/Q03GgGLm0

03.09.2025 22:10 — 👍 1    🔁 0    💬 0    📌 0
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New in @science.org: Researchers paired PEtracer with Vizgen’s MERSCOPE® to map how tumors evolve in vivo—showing how cell ancestry and local microenvironments shape growth and revealing new insights into tumor biology.

🔗 www.science.org/doi/10.1126/...

26.08.2025 16:45 — 👍 1    🔁 0    💬 0    📌 0

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