Adam de Smith

Adam de Smith

@adamdesmith.bsky.social

Assistant Professor at USC Center for Genetic Epidemiology. Researching the causes of childhood leukemia. sites.usc.edu/childhoodcancer/ record.umn.edu

1,214 Followers 153 Following 3 Posts Joined Oct 2023
4 months ago
Post image

πŸ“£Online now!
πŸ“„The impact of Indigenous American-like ancestry on risk of acute lymphoblastic #leukemia in Hispanic/Latino children
πŸ§‘β€πŸ€β€πŸ§‘ @charleston.bsky.social @adamdesmith.bsky.social & co
πŸ‘‰ bit.ly/47qXY3Q

1 3 0 0
1 year ago
Preview
Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed Most genetic variants associated with complex traits and diseases occur in non-coding genomic regions and are hypothesized to regulate gene expression. To understand the genetics underlying gene expre...

πŸ“’ Thrilled to see this out, an atlas of e/sQTL across multiple tissues and diverse ancestries in 14,324 TOPMed participants: www.medrxiv.org/content/10.1...

Grateful to the #TOPMed #Omics WG for giving me an opportunity to learn and contribute to this important work 🧬

36 15 1 1
1 year ago

Mind blown when I first saw this as a kid. Also when the Sesame Street characters just showed up to sing!

1 0 0 0
1 year ago
Preview
Regulated GATA1 expression as a universal gene therapy for Diamond-Blackfan anemia Gene therapy for Diamond-Blackfan anemia is constrained by dozens of causative mutations. Voit and colleagues develop a universal gene therapy through erythroid-lineage-restricted expression of GATA1 ...

Fantastic to have our preclinical study led by Richard Voit and colleagues on a universal gene therapy approach for #DiamondBlackfanAnemia by regulated GATA1 expression published earlier this week: www.cell.com/cell-stem-ce...

37 9 0 2
1 year ago

Would like to be added to this, thanks!

1 0 0 0
2 years ago
Post image

β€œBacktracking to the Future” !

Our new article in Leukemia describes the prenatal origins of childhood leukemia, and what we hope to learn by studying patient cord blood samples in the ReCord study (record.umn.edu)

rdcu.be/dt7ej

4 1 0 0
2 years ago
Post image

πŸ‘‹ Hi everyone! We're the Center for Genetic Epidemiology, here at Keck School of Medicine, USC! Please follow us for updates on our member's research, community engagement, and activities! Stay tuned for more content 🧬 πŸ§ͺ πŸ’» πŸ‘¨β€πŸ”¬ πŸ‘©β€πŸ”¬

20 6 0 0
2 years ago

Trying to be better with sharing work on here πŸ˜…
Check out our paper that identifies novel immune-mediated risk factors for glioma. We also found interesting genetic associations with survival and features of the tumor immune microenvironment 🧬 🧠

6 5 0 0