Fiber photometry analysis of spontaneous dopamine signals: The z-scored data are not the data Fluorescent sensors have revolutionized the measurement of molecules in the brain, and the dLight dopamine sensor has been used extensively to examine reward- and cue-evoked dopamine release, but only...

New Bluesky user here. I am excited to share our new preprint detailing how z-scoring can obscure experimental effects when analyzing prolonged fiber photometry recordings over time, also discussing when normalization is appropriate versus not. Please check it out!
www.biorxiv.org/content/10.1...