Nikki Lytle's Avatar

Nikki Lytle

@nikkilytle.bsky.social

Assistant Professor at the Medical College of Wisconsin. Tumor-microenvironment interactions and cell plasticity. Sources of joy: science, dogs, nature, comedy, sports

528 Followers  |  325 Following  |  3 Posts  |  Joined: 13.11.2024  |  1.6315

Latest posts by nikkilytle.bsky.social on Bluesky

Post image

🥳🚨🚨🚨Happy Monday! First publication from the lab is out! My PhD student Md Al Azim reviewed the complexity of ECM, its receptors and their role in cancer progression and therapeutic interventions! We thank Ryan Petrie for his valuable input,our reviewers and Matrix Biology for publishing our work!

14.04.2025 11:32 — 👍 19    🔁 4    💬 3    📌 2
Post image 26.03.2025 12:10 — 👍 17    🔁 13    💬 1    📌 8
Post image Post image Post image Post image

@standupforscience.bsky.social Madison. Take home message = call your representatives!!

07.03.2025 22:23 — 👍 6    🔁 0    💬 0    📌 0
Preview
Cell polarity proteins promote macropinocytosis in response to metabolic stress - Nature Communications Cancer cells rely on macropinocytosis to survive in a nutrient-deprived environment. Here, Lambies et al. identified various members of the cell polarity protein network as essential regulators of mac...

I'm thrilled to share our latest research, published in Nature Communications. This work highlights how pancreatic cancer cells hijack cell polarity proteins to regulate macropinocytosis and tumor metabolism, shedding light on potential therapeutic vulnerabilities.
www.nature.com/articles/s41...

04.12.2024 00:52 — 👍 70    🔁 16    💬 4    📌 0

I’d love to join your starter pack!

24.11.2024 01:46 — 👍 2    🔁 0    💬 0    📌 0
Preview
Single-cell RNA-sequencing of human spleens reveals an IDO-1+ Tolerogenic Dendritic Cell subset in pancreatic cancer patients that is absent in normal individuals. Local and systemic immunosuppression are prominent features of pancreatic cancer, rendering anti-tumor effector cells inactive and immunotherapeutic a…

Single-cell RNA-sequencing of human spleens reveals an IDO-1<sup>+</sup> Tolerogenic Dendritic Cell subset in pancreatic cancer patients that is absent in normal individuals. #PDAC www.sciencedirect.com/science/arti...

15.11.2024 21:17 — 👍 3    🔁 1    💬 0    📌 0

I’d love to be added!

15.11.2024 13:46 — 👍 0    🔁 0    💬 1    📌 0

I’m thrilled to share the Pancreatic Cancer Starter Pack! If you want to join DM go.bsky.app/2FHVVL6

15.11.2024 12:15 — 👍 5    🔁 7    💬 4    📌 1

@nikkilytle is following 20 prominent accounts