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Jesse Shapiro

@bjesseshapiro.bsky.social

Macrobe qui aime les microbes http://www.shapirolab.ca/

1,703 Followers  |  714 Following  |  403 Posts  |  Joined: 24.08.2023  |  2.888

Latest posts by bjesseshapiro.bsky.social on Bluesky

Ok, I can’t not cheer for Vlad Jr.

24.10.2025 17:21 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Sorry Toronto, but Montreal will be cheering for the Dodgers tonight!

24.10.2025 16:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
A black-and-white photo of Jackie Robinson wearing a Montreal uniform, holding a bat over his shoulder. He is dressed in a light jersey with "Montreal" written across the chest, a matching cap with an "M" logo, and pants with a belt. The background shows a crowd of spectators in a stadium.

A black-and-white photo of Jackie Robinson wearing a Montreal uniform, holding a bat over his shoulder. He is dressed in a light jersey with "Montreal" written across the chest, a matching cap with an "M" logo, and pants with a belt. The background shows a crowd of spectators in a stadium.

On Oct. 23, 1945, the news broke that Jackie Robinson had been signed to play with the Montreal Royals.
He would spend a season with the team before being promoted to the Brooklyn Dodgers on his way to the Hall of Fame.
This is his story.

🧡 1/12

23.10.2025 14:02 β€” πŸ‘ 83    πŸ” 22    πŸ’¬ 2    πŸ“Œ 2
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πŸ¦ πŸ“’If, like us, you lie awake at night wondering how cyanobacteria can be so good at adapting to any conditions, or if you just think they're cool and need an excuse to visit #Montreal, please consider submitting an abstract to our session by November 25th #ASLOSIL2026 www.aslo.org/aslo-sil-2026/

23.10.2025 14:23 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Non-conjugative plasmids limit their mobility to persist in nature Sabnis et al. explain why non-conjugative plasmids move at a low rate in nature. While increased mobility can easily evolve by incorporating phage DNA into plasmids, this is disadvantageous because it...

New paper with my (amazing) friend and mentor @jrpenades.bsky.social
Really looking forward to see what plasmid aficionados think of this one!!
With @asantoslopez.bsky.social @wfigueroac3.bsky.social Akshay Sabins and others
www.cell.com/cell-reports...

22.10.2025 13:12 β€” πŸ‘ 74    πŸ” 40    πŸ’¬ 1    πŸ“Œ 1

I’m very happy this is finally out! Here, we showcase the combination of BONCAT and SIP metaproteomics to uncover rare and active microbes driving anaerobic acetate turnover. We are excited to see what other microbial metabolisms and ecosystems this approach can help to illuminate! 🦠

21.10.2025 17:08 β€” πŸ‘ 28    πŸ” 14    πŸ’¬ 2    πŸ“Œ 2

Please share this with anyone who may be interested in a post-doc in Germany:

jobs.awi.de/Vacancies/20...

This is quite an exciting opportunity to push the boundaries of what is known regarding the molecular basis of the formation and demise of photosymbiotic relationships in marine habitats.

22.10.2025 10:36 β€” πŸ‘ 43    πŸ” 48    πŸ’¬ 1    πŸ“Œ 1

Why can’t I have more content like this?

21.10.2025 00:33 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
A supermarket aisle displaying various dairy products, including bags of milk and cartons of cream, with brands such as "Sealtest" and "Lactantia" prominently featured. The products are arranged on shelves, with some bags of milk in blue and red packaging in the foreground and various milk and cream cartons in the background.

A supermarket aisle displaying various dairy products, including bags of milk and cartons of cream, with brands such as "Sealtest" and "Lactantia" prominently featured. The products are arranged on shelves, with some bags of milk in blue and red packaging in the foreground and various milk and cream cartons in the background.

Outside of Canada, many assume that the entire country uses bagged milk.
The truth is, only part of Canada have bagged milk in the fridge.
But why? Well, it comes down when Canada made the transition to the metric system.
This is the story!

🧡 1/9

20.10.2025 13:02 β€” πŸ‘ 138    πŸ” 46    πŸ’¬ 3    πŸ“Œ 9

Very cool! Look forward to reading it :)

20.10.2025 23:13 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Habitat-specificity in SAR11 is associated with a few genes under high selection Abstract. The order Pelagibacterales (SAR11) is the most abundant group of heterotrophic bacteria in the global surface ocean, where individual sublineages

I'm delighted our paper is out: doi.org/10.1093/isme...
With new SAR11 isolate genomes and time-series metagenomes, we reveal coastal and offshore SAR11 ecotypes, identify associated metabolic traits, and pinpoint selective gene sweeps as a likely evolutionary driver to niche partitioning. 🌊🦠

20.10.2025 19:40 β€” πŸ‘ 24    πŸ” 18    πŸ’¬ 2    πŸ“Œ 1

And now NextStrain as well.

Next up, will GISAID start charging open-source community tools to have access?

That would completely shaft users who contributed to GISAID, where we never agreed to that and assumed GISAID would be good custodians of the data we contributed. They're not.

16.10.2025 19:48 β€” πŸ‘ 62    πŸ” 53    πŸ’¬ 9    πŸ“Œ 2
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Isolation, engineering and ecology of temperate phages from the human gut - Nature Human host-associated cellular products may act as induction agents for bacteriophages.

Very cool phage study from @jeremyjbarr.bsky.social's lab.

Isolation, engineering and ecology of temperate phages from the human gut
#microbiomesky #phagesky

15.10.2025 21:26 β€” πŸ‘ 15    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
MIT Faculty Searches MIT INSTITUTE FOR MEDICAL ENGINEERING AND SCIENCE FACULTY SEARCH

We are recruiting new faculty in IMES at MIT!

IMES (Institute for Medical Engineering and Science) is the MIT home of the famous HST program. As faculty are also appointed in a department at MIT, we have diverse research programs, all focused on human health.

faculty-searches.mit.edu/imes-search/

14.10.2025 20:08 β€” πŸ‘ 10    πŸ” 18    πŸ’¬ 0    πŸ“Œ 0
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Ecological constraints foster both extreme viral-host lineage stability and mobile element diversity in a marine community Phages are typically viewed as very rapidly evolving biological entities. Little is known, however, about whether and how phages can establish long-term genetic stability. We addressed this eco-evolut...

Phages evolve fast, or do they?
In oysters, some stay identical for years.
With >1,200 phages & 600 Vibrio genomes, we reveal long-term stability and new mobile elements.
Proud of this collaborative work across our teams (Roscoff-UdeM and @epcrocha.bsky.social www.biorxiv.org/cgi/content/...

12.10.2025 21:16 β€” πŸ‘ 86    πŸ” 50    πŸ’¬ 1    πŸ“Œ 2
A mural of road cycling racers and the inclined tower of the Olympic stadium are illuminated by the golden light of the setting sun. In the foreground, orange cones casually delimit an intersection under construction.

A mural of road cycling racers and the inclined tower of the Olympic stadium are illuminated by the golden light of the setting sun. In the foreground, orange cones casually delimit an intersection under construction.

Montreal scene

14.10.2025 22:26 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Bicentenary Early Career Research Fellowships | Biology, Medicine and Health | University of Manchester Find out about and apply for a Bicentenary Early Career Research Fellowship.

Three Bicentenary research fellowships on offer at @officialuom.bsky.social @fbmh-uom.bsky.social for exceptional ECRs with <3y postdoc experience

3yrs salary + Β£30k pa research expenses

Do you have a great idea & want to join @mermanchester.bsky.social?

www.bmh.manchester.ac.uk/research/sup...

09.10.2025 20:47 β€” πŸ‘ 21    πŸ” 39    πŸ’¬ 0    πŸ“Œ 1
Preview
a man in a blue jacket is crying and says " are you crying " ALT: a man in a blue jacket is crying and says " are you crying "

Reading the acknowledgments section of my student's PhD thesis...

09.10.2025 18:57 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Measles, Canada... 1,923 cases total

https://www.alberta.ca/measles

Measles, Canada... 1,923 cases total https://www.alberta.ca/measles

Meanwhile in Canada, there have been more reported measles cases in Alberta (cases: 1,923; population: ~5M) than reported in all of the US this year (cases: 1,563, population: ~340M).

Consequence: "The Americas region is at risk of losing its measles-free status..."

globalnews.ca/news/1146683...

09.10.2025 11:59 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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Trade-offs between phage resistance and conjugative ability shape the ecological and evolutionary response of a multidrug resistance plasmid to plasmid-dependent phage Phage therapy is a promising alternative to antibiotics to treat multidrug resistant infections. Plasmid dependent phages (PDPs) are particularly attractive as therapeutics because they can both kill ...

New pre-print www.biorxiv.org/content/10.1...
Plasmid-dependent phage (PDPs) are ubiquitous, but the selective pressures that they impose on plasmids are not well understood. Project led by Daniel Cazares in collaboration with @brockhurstlab.bsky.social!
#phagesky#microsky

09.10.2025 10:07 β€” πŸ‘ 50    πŸ” 28    πŸ’¬ 1    πŸ“Œ 0

Bon conseil ;)

09.10.2025 00:13 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Would love to. Let’s keep in touch.

08.10.2025 11:51 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Experimental evolution of a mammalian holobiont: bank voles selected for herbivorous capability evolved distinct and robust gut bacterial communities Abstract. According to the β€œhologenome” theory of evolution natural selection and evolution can act through a conglomerate biological unit, the β€œholobiont”

Pleased to share new work tinkering with and testing the concept of the holobiont
@isme-microbes.bsky.social

"Experimental evolution of a mammalian holobiont: bank voles selected for herbivorous capability evolved distinct and robust gut bacterial communities"
🌾🐭🦠

academic.oup.com/ismecommun/a...

12.09.2025 17:02 β€” πŸ‘ 14    πŸ” 10    πŸ’¬ 1    πŸ“Œ 2

Around Montpellier! Exact location TBA, depends on the quality of local bike routes ;)

07.10.2025 21:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Fall 2026 to summer 2027! Want to come visit? Will you be nearby?

07.10.2025 21:03 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A photo of a cycling map of France on a table beside a glass of beer on a table in a bar.

A photo of a cycling map of France on a table beside a glass of beer on a table in a bar.

Sabbatical planning: step 1.

07.10.2025 20:24 β€” πŸ‘ 39    πŸ” 0    πŸ’¬ 3    πŸ“Œ 0
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Disability in ecology and evolution In this TrendsTalk series 'Disability in ecology and evolution' in Trends in Ecology and Evolution, we will be hearing from people about their experiences being disabled in ecology and evolution. We a...

www.cell.com/trends/ecolo...

New entry into the Disability in Ecology and Evolution series in TREE featuring me :)

07.10.2025 16:24 β€” πŸ‘ 19    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
Glass buildings with a paved path in between (gray, with blue lines)

Glass buildings with a paved path in between (gray, with blue lines)

My department @geographieudem.bsky.social is looking for a professor in human geography specializing in the study of social-ecological transformations, political ecology, climate change, environmental justice and/or the geography of risks and infrastructures. Deadline November 10, share widely!

06.10.2025 19:19 β€” πŸ‘ 10    πŸ” 9    πŸ’¬ 2    πŸ“Œ 0
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Genomic correlates of tailocin sensitivity in Pseudomonas syringae Abstract. Phage-derived bacteriocins, also referred to as tailocins, are structures encoded by bacterial genomes and deployed into the extracellular enviro

Here’s published version of our manuscript using GWAS to investigate tailocin sensitivity in Pseudomonas syringae. TL:DR pretty clear LPS is tailocin receptor but also that P.syringae often completely swaps out its entire O antigen biosynth pathway w/ recombination

academic.oup.com/g3journal/ad...

06.10.2025 18:57 β€” πŸ‘ 36    πŸ” 11    πŸ’¬ 1    πŸ“Œ 1
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Resistance mutation supply modulates the benefit of CRISPR immunity against virulent phages Only a fraction of bacterial genomes encode CRISPR-Cas systems but the selective causes of this variation are unexplained. How naturally virulent bacteriophages (phages) select for CRISPR immunity has...

New preprint!

Ever wondered why only a fraction of genomes encode CRISPR immunity? 🧬 🦠

Turns out CRISPR is rarely beneficial against virulent phages, being most beneficial against those for which resistance mutations are rare!

An epic effort by Rosanna Wright

www.biorxiv.org/content/10.1...

06.10.2025 06:27 β€” πŸ‘ 93    πŸ” 46    πŸ’¬ 3    πŸ“Œ 1

@bjesseshapiro is following 20 prominent accounts