@mesospim.bsky.social
Light-sheet microscopes for large samples. Open source hardware and software. Run by @nvladimus.bsky.social and @voigtvision.bsky.social Overview: www.mesospim.org Mailing list: http://eepurl.com/hPBRhj Forum: forum.image.sc/tag/mesospim
Thanks to AI, the comprehensive #mesoSPIM-control documentation is finally here π
mesospim.github.io/mesoSPIM-con...
π¨Preprint alertπ¨ Mapping of 3D collagen architecture with #tissueclearing, @mesospim.bsky.social #lightsheet #Microscopy, the Schmidt #multiimmersion microscope objective & #deeplearning in healthy tissue & wound healing by Wout Houbart & Thomas Naert & Co! www.biorxiv.org/content/10.6...
We're still exploring how to improve LSFM performance with "big" detection air objectives, where field curvature often limits achievable FOV. Here, Steven introduces curvedASLM, a method to dynamically correct field curvature (along one axis) in axially scanned setups www.biorxiv.org/content/10.6...
Fun to see photos from the @mesospim.bsky.social Symposium this last October.
The 10 Years of #mesoSPIM Symposium was a blast! ππThe excitement was palpable, and we were all inspired. Three days flew by fast! Thanks to all the attendees, speakers, organizing team, and our sponsors for making it such a memorable event! Let's shape the next 10y of microscopy together! πͺβ€οΈπ¬
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Start: 01.12.2025 (or on mutual agreement)
β³ Application deadline: 31.10.2025
Curious? Learn more and apply here: t.uzh.ch/1U3
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In this role, you will:
- Clear, stain, and image biological tissues
- Process and share imaging datasets
- Support and train platform users
Weβre looking for candidates with lab experience, curiosity, and practical knowledge in tissue processing and fluorescence microscopy.
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Job opportunity at the University of Zurich! π’
We are looking for a ππππ¨π«πππ¨π«π² ππππ‘π§π’ππ’ππ§ / πππ¬πππ«ππ‘ ππ¬π¬π’π¬πππ§π (ππ%) to join our Microscopy Innovation Platform (MIP), an open-source initiative focused on advancing and making light-sheet and multiphoton microscopy accessible to researchers.
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Both are experienced clinical pathologists who are master users of #mesoSPIM and developed their own way of staining and clearing the most challenging tissues in their clinical practice. Want to learn which method will work best with your samples? Join us at #mesoSPIM2025 t.uzh.ch/1Ss
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Our invited speakers Dr. Anna Maria Reuss and Dr. Hei Ming Lai show astonishing results in this field with their new methods, #aDISCO and #INSIHGT, respectively, at the #mesoSPIM2025 symposium.
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Is it possible to stain specific proteins and cell types in old formalin-fixed human tissues and make them transparent for light-sheet imaging and clinical 3D diagnostics?
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Final program of the 10-year #mesoSPIM2025 Anniversary Symposium, October 13-15 in Zurich! Amazing lineup of speakers: biologists, physicists, developers, computer scientists and industry experts! Join us to learn, present, and connect! Registration until Sept. 15. www.adabd.uzh.ch/en/events/me...
π£We have opened our official User Forum: forum.image.sc/tag/mesospim
In this forum you can connect with π¬developers and the image analysis experts. Ask your burning questions about the #mesoSPIM hardware, software, and image processing, or help the beginners to get started!
Tip: use project tags!
How to image across scales from organs to synapses, unravel biological mechanisms and handle massive data?
Learn more from @adamkglaser.bsky.social, senior scientist at the Allen Institute and the lead developer of #ExA-SPIM technique, at the #mesoSPIM2025 Symposium, Oct 13-15.
π₯How can light-sheet help reveal dark matter?π₯
Join Prof. Laura Baudis @lbaudis.bsky.social at #mesoSPIM Symposium, Oct 13β15 in Zurich or online, to see how light-sheet fluorescence microscopy π¬ is used to image nuclear β’οΈ recoil tracks to detect elusive particles!
Register now: t.uzh.ch/1Ss
What a pleasure to image such samples π₯°
#Deeplearning-based #CRISPR DNA integration and editing by Thomas Naert & SΓΆren Lienkamp & Co with lots of @mesospim.bsky.social #lightsheet #Microscopy data of tadpoles (and some taken with the #Schmidt #multiimmersion objective prototype!) π¬πΈ www.nature.com/articles/s41...
Weβre excited to welcome @kevin-dean.bsky.social to the #mesoSPIM2025 Symposium! Explore his innovations in Multiscale Cleared-Tissue Axially Swept Light-Sheet Microscopy for imaging from organ to subcellular levels.
πΊοΈOct 13β15 | Zurich & hybrid
Interested? Register now: t.uzh.ch/1Ss
Abstract Submission Deadline: TOMORROW, July 15-th π
π Call for Abstracts! π
Abstract deadline approaching! 10 years of #mesoSPIM initiative β join us at the symposium for talks, demos & posters on microscopy, tissue clearing, and data analysis!
π October 13-15, 2025
πΊοΈ Zurich, Switzerland, but also online.
www.adabd.uzh.ch/en/events/me...
Speakers include @voigtvision.bsky.social @adamkglaser.bsky.social @christellelangevin.bsky.social @preibischs.bsky.social @jsdaniel02.bsky.social @nvladimus.bsky.social and many others! Poster design by @mgarbelli.bsky.social, cover image by Anna Maria Reuss.
Highlights:
π£οΈ Keynotes & lightning talks
π©βπ¬ Maker Day for microscope builders
π€ Meet devs, users & industry
Join us to shape the future of open-source microscopy!
#mesoSPIM2025 #openscience
Submit your work in any of these areas:
π§ Bio/Neuro/Phys imaging
π§Ό Tissue clearing techniques
π₯οΈ Image analysis tools (open or commercial)
π§ Hardware and software (open or commercial)
Talks, posters & demos welcome!
Abstract submission: ema.uzh.ch/R7YRN
π Call for Abstracts! π
Weβre celebrating 10 years of #mesoSPIM #opensource initiative β join us at the symposium for talks, demos & posters on open-source light-sheet microscopy, tissue clearing, and imaging!
Dates: October 13-15, 2025
Location: Zurich, Switzerland
Registration: ema.uzh.ch/R7YRN
Happy imaging!
π¬ On June 6, we inaugurated the first #MesoSPIM in France at INRAE Jouy-en-Josas & ENS Paris-Saclay! A big thanks to @nvladimus.bsky.social , @mgarbelli.bsky.social ,Angeliki Vavladeli & all speakers and sponsors. Exciting step forward for #opensource imaging & interdisciplinary science! #microscopy
Did you know that Universite Paris Saclay has its own Benchtop #mesoSPIM? Interdisciplinary team lead by @christellelangevin.bsky.social has built their own setup, the first in France, and organized an inauguration symposium! Cleared baby sturgeon or trout? They have it! French bioimaging is strong!
New chamber mount design for our @mesospim.bsky.social - magnetic kinematic bases from @thorlabs.bsky.social for the win! 3D printed (for now) bases hold the chamber snugly for precise positioning between experiments. Fill port on the front allows for media addition without disturbing imaging.
Looking forward to the @mesospim.bsky.social #lightsheet #Microscopy anniversary symposium in October with @preibischs.bsky.social @adamkglaser.bsky.social @christellelangevin.bsky.social & many more! And to the next mesoSPIM decade! π¬ Thanks @nvladimus.bsky.social & Co for organizing it!