Laura Cantini's Avatar

Laura Cantini

@cantinilab.bsky.social

PI of the machine learning for Integrative genomics lab @pasteur.fr and @CNRS.bsky.social #NewPI #DiversityEqualityInclusion Single-cell, multi-omics, machine learning

863 Followers  |  229 Following  |  15 Posts  |  Joined: 13.11.2024  |  2.1651

Latest posts by cantinilab.bsky.social on Bluesky

Brain Surfaces of 70 primate species

Brain Surfaces of 70 primate species

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To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, youโ€™ll be surprised!

๐ŸงตThread on our new preprint with @r3rt0.bsky.social , doi.org/10.1101/2025...

27.07.2025 17:26 โ€” ๐Ÿ‘ 459    ๐Ÿ” 209    ๐Ÿ’ฌ 13    ๐Ÿ“Œ 23
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SPONGE: simple prior omics network GEnerator AbstractSummary. Gene regulatory networks modelled from experimental data can be improved through the use of prior biological knowledge, e.g. transcription

GRN inference algorithms often build on prior knowledge of e.g. TF binding. Build up-to-date priors with our new tool SPONGE, now out in Bioinformatics: academic.oup.com/bioinformati...

28.07.2025 09:46 โ€” ๐Ÿ‘ 11    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

MOTL is finally out in Genome Biology! Work led by David Hirst and @anaisbaudot.bsky.social

If you are interested in multi-omics matrix factorization when few samples are available (e.g. rare diseases), have a look at it!

#multiomics #machinelearning #transferlearning

26.07.2025 10:55 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Going back to Paris after four days of awesome science! Really happy to have contributed to #ISMBECCB2025 with a keynote talk in the @netbio.bsky.social.

Thanks again @anaisbaudot.bsky.social and all #NetBio commitee for the invitation!

@institutpasteur.bsky.social #singlecell #AI #netbio

24.07.2025 08:47 โ€” ๐Ÿ‘ 6    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Group Leader (282908) | University of Oslo Job title: Group Leader (282908), Employer: University of Oslo, Deadline: Monday, September 8, 2025

๐Ÿšจ We're hiring! NCMBM @ncmbm.bsky.social is looking for 2 new group leaders to join our vibrant research community. Ready to build your own group with strong support and a solid startup package?

Interested and attending #ISMBECCB2025? Letโ€™s connect!

๐Ÿ”— www.jobbnorge.no/en/available...

22.07.2025 06:12 โ€” ๐Ÿ‘ 37    ๐Ÿ” 27    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿšจ Excited to announce our first keynote for #NetBio 2025: Laura Cantini (@cantinilab.bsky.social)!

She is sharing cutting-edge work on multi-modal learning for single-cell data integration, tackling how to combine diverse omics and spatial data to unlock new insights into cellular heterogeneity.

22.07.2025 10:49 โ€” ๐Ÿ‘ 9    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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scConfluence: single-cell diagonal integration with regularized Inverse Optimal Transport on weakly connected features - Nature Communications The abundance of unpaired multimodal single-cell data drives the need for improved integration methods. Here, authors introduce scConfluence, a method combining uncoupled autoencoders with regularized...

For more infos on the presented works
scPRINT: www.nature.com/articles/s41...
scConfluence: www.nature.com/articles/s41...
STORIES: www.biorxiv.org/content/10.1...

20.07.2025 14:08 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Flying to Liverpool for #ISMBECCB2025 @iscb.bsky.social. This year the lab is well represented with @jkobject.com presenting scPRINT in #MLCSB, Jules presenting two posters at #MLCSB: scConfluence and STORIES. I will finally, give a keynote at #NETBIO. Come to see us at the conference!

20.07.2025 14:05 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Fantastic opportunity to launch your research group following the @embl.org model in a great environment with a solid startup package and access to state-of-the-art resources.

Join us at the @ncmbm.bsky.social, part of the @nordicembl.bsky.social, at @uio.no

Feel free to reach out if you have Qs.

03.07.2025 10:24 โ€” ๐Ÿ‘ 8    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Leveraging data as a patientโ€“scientist: frustrations and opportunities Nature Reviews Nephrology, Published online: 19 June 2025; doi:10.1038/s41581-025-00968-9The transition from data scientist to patientโ€“scientist has given me new perspectives into clinical research and strengthened my commitment to open science. Although limitations on data availability have led to frustration, collaboration bodes well for a future in which patients will have access to more personalized information.
19.06.2025 13:57 โ€” ๐Ÿ‘ 10    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
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Two weeks ago, I had the pleasure to discuss the research activity of my team @institutpasteur.bsky.social in the panel discussion "How is AI and data-driven innovation reshaping oncology" at @parissaclay.bsky.social SPRING 2025 in @ecolepolytechnique.bsky.social

#ParisSaclaySPRING #SPRING25

04.06.2025 21:04 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Kicking off our afternoon session, @cantinilab.bsky.social discusses her dual approach to capture both multi-modal dimensionality reduction and molecular network inference. She gave a very nice overview of her work!

#NetBioMed2025 #NetSci2025 @verapancaldi.bsky.social

02.06.2025 12:27 โ€” ๐Ÿ‘ 5    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Before lunch break Elma Dervic gave us a very quick talk on how to build comorbidity networks from data. I loved her visualization through time. More amazing talks at #NetBioMed2025 after lunch, so stay tuned! #NetSci2025 @verapancaldi.bsky.social

02.06.2025 10:33 โ€” ๐Ÿ‘ 4    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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After coffee break Anna Niarakis discusses her approach to #digitaltwins, a novel conception to treat complex human pathologies. If we haven't been able to build artificial agents capable of openended evolution, can we truly build biological digital twins? #NetSci2025 #NetBioMed2025

02.06.2025 09:28 โ€” ๐Ÿ‘ 9    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Now @lmrocha.bsky.social goes deeper into the #digitaltwins paradigm, discussing how to build multiscale models for this purpose. What's the temporal limit when building these complex models? Can we build something as complex as biological architectures?

#NetBioMed2025 #NetSci2025

02.06.2025 10:02 โ€” ๐Ÿ‘ 6    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Iker Nuรฑez-Carpintero shows us his integrative #multilayer approach to explore rare neuromuscular disorders. Particularly he's focusing on cardiac and skeletal muscle myopathies. Join us at #NetBioMed2025, a @netsciconf.bsky.social satellite at #NetSci2025!

02.06.2025 10:20 โ€” ๐Ÿ‘ 5    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Kristel Van Steen kicks off our #NetBioMed2025 Satellite discussing how to use #networkscience to develop individual medical networks, going towards personalized medicine!

@netsciconf.bsky.social @verapancaldi.bsky.social

02.06.2025 07:35 โ€” ๐Ÿ‘ 9    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Our second talk of the day corresponds to Natasa Przulj, who gave us a detailed explanation on how to use #AI techniques in order to build #complexnetworks based on multi-omics!

#NetBioMed2025 #NetSci2025 @verapancaldi.bsky.social

02.06.2025 07:39 โ€” ๐Ÿ‘ 5    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

@netsciconf.bsky.social crossing Holland on my way to Maastricht for @netbiomed2025.bsky.social Join us tomorrow at FASOS for a great day of network biomedicine talks!

01.06.2025 16:34 โ€” ๐Ÿ‘ 3    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

Super cool to see scPRINT, work of my team led by @jkobject.com, featured by @cnrsbiologie.bsky.social

To access the work www.nature.com/articles/s41...

19.05.2025 08:06 โ€” ๐Ÿ‘ 6    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Happy to contribute to this wonderful meeting!

Thanks to @silviagrigolon.bsky.social @hugowioland.bsky.social and all co-organizers for the invitation !

19.05.2025 08:03 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Save the date poster of the Physics & Life days, division of the French Physical Society.

Save the date poster of the Physics & Life days, division of the French Physical Society.

Save the date for the 3rd edition of the Physics & Life days, division of the French Physical Society, October 2-3 at the Institute Jacques Monod, Paris.
More info coming soon!
Co-organised with Silvia Grigolon & Morgan Chabanon.
@sfp-physique.bsky.social @ijmonod.bsky.social

15.05.2025 14:20 โ€” ๐Ÿ‘ 14    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
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Bonsai: Tree representations for distortion-free visualization and exploratory analysis of single-cell omics data Single-cell omics methods promise to revolutionize our understanding of gene regulatory processes during cell differentiation, but analysis of such data continues to pose a major challenge. Apart from...

Here it is! Bonsai. Now there is really no more excuse for using t-SNE/UMAP. Bonsai not only makes cool pictures of your data. It actually rigorously preserves its structure. No tunable parameters. Incredible work by @dhdegroot.bsky.social.
I'm so excited about this!
www.biorxiv.org/content/10.1...

09.05.2025 10:49 โ€” ๐Ÿ‘ 320    ๐Ÿ” 103    ๐Ÿ’ฌ 8    ๐Ÿ“Œ 13

Looking forward to @netbiomed2025.bsky.social @netsciconf.bsky.social thanks @verapancaldi.bsky.social and all organizers for the invitation!

14.05.2025 15:13 โ€” ๐Ÿ‘ 5    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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How can we design #machinelearning methods able to co-analyze the numerous available #omics data and translate them into actionable biological knowledge? @cantinilab.bsky.social will answer this and other exciting questions related to single-cell data integration! #NetBioMed2025 #NetSci2025

14.05.2025 13:33 โ€” ๐Ÿ‘ 5    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2

Our new call for VIB.AI group leaders is online! Junior and senior positions available to develop innovative ML methods in biology. With professorship at CS or Medical Faculty. Deadline 14th June. DM for more info.

26.04.2025 11:00 โ€” ๐Ÿ‘ 32    ๐Ÿ” 21    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

๐Ÿšจ Two PhD positions available in the lab of @arnaumontagud.bsky.social in I2SysBio ๐Ÿ‡ช๐Ÿ‡ธ. Both are related to simulations of biological tissues

06.05.2025 16:10 โ€” ๐Ÿ‘ 3    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ“ข Exciting news! We will soon open two PhD positions at @i2sysbio.bsky.social @csic.es, in research projects in collaboration with the @bsc-cns.bsky.social. Both are related to tools to simulate biological tissues. Hereโ€™s the description of the open positions. #PhDpositions #PhDOpportunities
๐Ÿ‘‡

06.05.2025 08:46 โ€” ๐Ÿ‘ 10    ๐Ÿ” 10    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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๐Ÿšจ New preprint: Topography Aware Optimal Transport for Alignment of Spatial Omics Data

We present our new alignment framework TOAST www.biorxiv.org/content/10.1...

22.04.2025 09:37 โ€” ๐Ÿ‘ 31    ๐Ÿ” 17    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
scPRINT: pre-training on 50 million cells allows robust gene network predictions - Nature Communications Authors present a state-of-the-art cell foundation model trained on 50โ€‰million cells. They show that the model generates a meaningful gene network and has zero-shot ability in various tasks.

.@jkobject.com @cantinilab.bsky.social @gabrielpeyre.bsky.social present a foundation model trained on 50 million cells, generating a meaningful gene network with zero-shot ability. #AIxBio @natcomms.nature.com

www.nature.com/articles/s41...

21.04.2025 20:25 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@cantinilab is following 20 prominent accounts