Christal Sohl

Supreme Court allows Trump administration to terminate $783 million in NIH grants linked to DEI initiatives By a vote of 5-4, the Supreme Court on Thursday agreed to allow the National Institutes of Health, the largest public funding source for biomedical research in the world, to […]

SCOTUSBlog story about NIH Grant Termination case

www.scotusblog.com/2025/08/supr...

CNN headline that reads: "Supreme Court allows Trump to block $783 million in National Institutes of Health grants for now"

The Supreme Court just greenlit Donald Trump gutting nearly $800 MILLION for medical treatments and cures.

Congress approved this funding for a reason: it saves lives.

This is disgraceful, and families will suffer.

A retired colleague and a younger cousin are joining me in this, so this campaign has cross generational appeal. RFKJ is a quack spreading deadly misinformation about vaccines and other public health issues. He is completely unqualified to lead HHS. #standupforscience @standupforscience.bsky.social

This is not the time to step back from diversity, equity, and inclusion Recently, I exchanged views with a prominent Ivy League scientist who was complaining about the minority students and junior faculty applying to his program. He claimed that the university, through diversity, equity, and inclusion (DEI) policies, was ...

This is not the time to step back from diversity, equity, and inclusion | Science www.science.org/doi/10.1126/...

BREAKING: Scientists are staging a “science fair” in the lobby of a Congressional building to tell elected officials about the critical knowledge the US will lose because their research grants have been canceled.

Sec. 7. Enforcement and Oversight. (a) Each agency head shall establish internal processes to evaluate alleged violations of the requirements of this order and other applicable agency policies governing the generation, use, interpretation, and communication of scientific information. Such processes shall be the responsibility, and administered under the direction, of a senior appointee designated by the agency head and shall provide for taking appropriate measures to correct scientific information in response to violations, consistent with the requirements and procedures of section 515 of the statute commonly known as the Information Quality Act, Public Law 106-554, appendix C (114 Stat. 2763A-153). The designated senior appointee may also forward potential violations to the relevant human resources officials for discipline to the extent the potential violation also violates applicable agency policies and procedures. The designated senior appointee may consult appropriate officials with scientific expertise when establishing such processes. (b) The processes created under this section are, unless otherwise required by applicable law, the sole and exclusive means of evaluating and, as applicable, addressing alleged violations of this order and other agency policies governing the use, interpretation, and communication of scientific information.

The lede was buried.

Disappointed in your crypto vote :(

How Vaccines are Developed and Approved for Use Learn how vaccines are developed and approved for use.

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RFK Jr. says childhood vaccines weren’t tested and that COVID boosters need full trials every year.
That’s not how vaccines—or science—work. Time for a #FactCheckFriday!

Let’s talk about how vaccines are tested, and how this kind of talk puts real people at risk.

www.cdc.gov/vaccines/bas...

a cartoon of a man holding a frying pan and a spoon with red alert written above him ALT: a cartoon of a man holding a frying pan and a spoon with red alert written above him

ATTENTION: NSF GRANT RECIPIENTS

We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.

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the word alert is in a purple circle ALT: the word alert is in a purple circle

ACTION ITEM-----ACTION ITEM

Implementation of Schedule F

This is what a lot of us have been worried about.

This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.

BUT THERE IS A COMMENT PERIOD...

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HAPPY TAX DAY!
How much would you spend on a year of tornado warnings? The average US taxpayer spends only $4 a year to help fund the NWS. It’s a smart investment—every $1 invested in NWS yields approx. $73 in social benefits.
🌪️❄️ Support science. Support the NWS.
Stay tuned for more this #TaxDay

Trump admin pulled Princeton's grants, citing their NOAA-funded research "suggests that the Earth will have a significant fluctuation in its water availability as a result of global warming. Using federal funds to perpetuate these narratives does not align with the priorities of this Administration"

Maybe not all mutations are exactly the same!

We are so grateful for the hard work of our students and trainees, and of our collaborators both at SDSU and in Germany, that allowed us to undertake this large and fun project! (6/6)

Via RNAseq, we see pro-tumor pathways turned on that have these R132Q-expressing tumors looking a little bit more like WT IDH1-driven gliomas, which typically are more aggressive and have worse outcomes. (5/6)

Cell lines expressing IDH1 R132Q have more D2HG than those expressing R132H...and mouse xenografts expressing R132Q have more D2HG in the tumors and sera, too. Tumors are bigger. (4/6)

We've been working a few years to try to figure this out, & our wonderful team of scientists w/ biochemical, computational, & cell biology expertise have showed that catalytic efficiency DOES matter! (3/6)

One of the catalytically weirdest mutants is R132Q -- it makes buckets of D2HG, especially compared to the more common mutations seen in patients, like R132H.
But does this catalytic efficiency translate to more D2HG in a cell? In a tumor? (2/6)

Catalytically distinct metabolic enzyme isocitrate dehydrogenase 1 mutants tune phenotype severity in tumor models Mutations in isocitrate dehydrogenase 1 (IDH1) impart a neomorphic reaction that produces D-2-hydroxyglutarate (D2HG), which can inhibit DNA demethylases to drive tumorigenesis. Mutations affect resid...

🚨New paper alert!🚨J Biol Chem
www.jbc.org/article/S002...
We have a long-standing interest in the many mutations in isocitrate dehydrogenase 1 (IDH1) in cancer patients -- many alterations @ residue have been reported (eg R132H/C/G/S/L), all able to make the tumor-driving oncometabolite D2HG (1/6)

@sandiegostate.bsky.social Professor Eunha Hoh and her lab are featured in Out of Plain Sight, a documentary based on the LA Times investigation into the environmental crisis of offshore DDT dumping.

Watch the debut at the San Diego Asian Film Festival on April 25: sdaff.org/spring2025/m...

Lawsuit aims to broadly overturn NIH’s grant terminations Multiple groups and NIH-funded scientists challenge agency’s decision as arbitrary and capricious

Breaking news: A new lawsuit seeks to challenge the National Institutes of Health’s decisions to abruptly terminate hundreds of grants, totaling more than $2.4 billion, over the past month. scim.ag/3DZnylL

I may be tired and a little hoarse, but as I said again and again on the Senate floor, this is a moment where we cannot afford to be silent, when we must speak up.

Booker telling the story of his father's experience with Parkinson's and using it to speak about the importance of funding research on science and health.

Booker, after speaking for more than 24 hours and breaking Thurmond's record, is still standing and still speaking--using his time to warn his colleagues and his country about the dangers of defunding universities and defunding scientific research.

Live: Speaking on Trump, Musk, and America’s Moral Moment on the Senate Floor | Senator Cory Booker YouTube video by Senator Cory Booker

I’ve taken the Senate floor and will speak for as long as I’m physically able to lift the voices of Americans who are being harmed and not being heard in this moment of crisis. Watch here:

Did You Work on a Terminated NIH Grant? ProPublica Wants to Hear From You. The National Institutes of Health is canceling grants that are seen as conflicting with the Trump administration’s priorities. We want to hear from researchers who have been affected.

Did You Work on a Terminated NIH Grant? ProPublica Wants to Hear From You. www.propublica.org/getinvolved/...

Grant cancelled? 👇

If the constitution is still in operation, Trump's executive order abolishing the Department of Education is just a suggestion.

If Trump can abolish the Department of Education with an executive order, then the constitution is just a suggestion.

Adding CBC News to my daily reading

(which includes The Guardian, Boston Globe, Philadelphia Inquirer)

Mourning the loss of my lifelong standbys, now sane-washing a rapid slide into autocracy

RIP Washington Post, NYT, LA Times

NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.

New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024.

That's not to mention the countless lives that biomedical research has saved.

Show me a better investment than that.
www.forbes.com/sites/michae...

Protest sign with black text listing a subset of words that were flagged for further scrutiny by federal agencies (including “bias” “increase diversity” “disability” “racism” “trauma” “victim” and “women”). In large red letters over top, the words “These words kill fascists” is written, an homage to Woody Guthrie.

We will keep fighting and standing up for science.

(and thank you so much for being a lifeline for all of us during this...hope you're taking care of you as best as you can during all of this!)