oZgun Gokce

Superpower Suicide: How RFK Jr. Just Kneecapped American Science Canceling mRNA vaccine development isn’t just bad policy – it’s a national act of self-sabotage in the race for global scientific leadership.

yep demwinsmedia.substack.com/p/superpower...

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Excited to co-organize a session with @mootspoints.bsky.social at #TRAC2025!
🧬 Integrating Ancient DNA with Archaeological Theory and Practice
We welcome papers on mobility, migration, & identity in the Roman world and beyond.
📢 Call for abstracts now open! Please spread the word.
#aDNA #science

I love humanity… it’s people I can’t stand.

Dual lineage origins contribute to neocortical astrocyte diversity - Nature Communications Astrocytes display diverse molecular and functional features in the brain, but the developmental origins of this heterogeneity are not well understood. Here, the authors show that two separate progeni...

🚨 First paper from the Bocchi lab out now in @natcomms.nature.com!
We show that astrocytes in the cortex arise from not one, but two distinct progenitor lineages, each giving rise to specialized subtypes with distinct roles.
Here the story📖 doi.org/10.1038/s414...

Ok, let's start this thing here with my favorite 3D animation connected to our recent paper on structure and interactions of beta cell primary cilia. www.nature.com/articles/s41...
Still super ecited about cilia-axon contacts in the pancreas.

Workshop 2025 About the workshop This workshop will cover array tomography (AT) technology with a focus on “simple and affordable” workflows based on serial ultramicrotomy and imaging. The practicals include...

Our 2nd Array Tomography Workshop will be in November in Buenos Aires and there is still time to apply! Five days of hands-on learning, discussions and talks + gorgeous electron microscopy and immunofluorescence. Focus on simple and affordable workflows.
www.arraytomography.org/workshop-202...

Well deserved!

Excited to share that our study on the role of the liver in #CancerCachexia is out in Cell! 😀 🧬

We found that the liver plays an active role in driving weight loss in cancer through disruption of the circadian regulator REV-ERBα and secretion of catabolic hepatokines

www.cell.com/cell/fulltex...

Fell in love with the neuropathology community 🧠 brilliant, selfless minds working to make brain donations meaningful for Donors, their families and scientists. @drneurochic.bsky.social & Hemali Phatnani’s leadership, we outlined a bold new vision in @cp-neuron.bsky.social lnkd.in/e7YxwrES

Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration Murray et al. introduce “transformative neuropathology” through dynamic, technology-integrated approaches to accelerate tissue-based discoveries and offer actionable strategies to strengthen brain ban...

Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration @cp-neuron.bsky.social www.cell.com/neuron/fullt...

Was a lot of fun working on this piece with Ben Clayton for @annualreviews.bsky.social
Reactive astrocyte heterogeneity is a thoroughly exciting and complicated problem... lots of exciting discoveries in recent years.

www.annualreviews.org/content/jour...

What are "omics"?
A good schematic
cell.com/neuron/fullt...
could add epigenomics, immunomics, microbiomics, glycomics, exposomics, etc

Waiting for paper reviews in the summer

Redhaired scientist here: are you the redhaired geek in group? If yes you won’t answer this due to a gruesome situation

A timely, argument on why we still animal research now when AI can write songs:

Why We Still Need Animal Research in a World of AI and Organoids The portrayal of uncaring scientists without any thought for the animals being used in their research is far from the truth.

While I’m a big fan of new technologies that help us study human biology…there’s still no replacement for animal research! See my article in Gen News. www.genengnews.com/topics/trans...

FDA-NIH Workshop: Reducing Animal Testing The FDA is hosting a workshop on reducing animal testing. The workshop is open to current FDA and NIH employees.

The NIH is asking scientists and the public to comment on plans to drastically limit animal model research. If you think animal models remain important tools for basic and clinical research tell them! Click the link below and scroll down to send your comments!

www.fda.gov/news-events/...

FDA-NIH Workshop: Reducing Animal Testing The FDA is hosting a workshop on reducing animal testing. The workshop is open to current FDA and NIH employees.

Does everyone know there is a comment period re: changes in animal research at NIH? I didn't. Closes July 14. The scientific community need to respond en masse. I asked university leadership to distribute to reach our colleagues not on social media, you can too

go.pardot.com/e/858023/duc...

We are excited to share our latest research on oligo-vascular interactions at the GLIA 2025 meeting. #GLIA2025

Interested in OPC/OL biology and blood vessels? Visit our posters:

T18-015B (presented by Emilia Korhonen; Wed)
T18-016C (presented by Carla Ramunno; Thu)

@gliameeting.bsky.social‬

great to meet! is there any link between Wilma and Felix arm bandage? muscle integrity testing? 🐾

The Republican spending bill is a historic theft that will take from the poor to give to the already-rich.

Republicans passed this knowing people will die.

They know people will lose their health care.

They know children will go hungry.

They will own the tragic results. We can't let them forget.

Sainsc: A Computational Tool for Segmentation‐Free Analysis of In Situ Capture Data (Small Methods 5/2025) Segmentation-Free Analyses Sainsc: a new tool for efficient whole organism spatial transcriptomics data analysis at the nanometre scale. Shown is a blended composite spatial map of total gene express...

Spatial transcriptomics - helping authors wow reviewers with pretty pictures (... and interesting spatial biology).. and making it possible for bioinformaticians to submit journal cover art! Our Sainsc tool is featured as the back cover for Small Methods: onlinelibrary.wiley.com/doi/10.1002/...

Acute stress causes sex-specific changes to ventral subiculum synapses, circuitry, and anxiety-like behavior - Nature Communications Here, the authors systematically interrogate the impact of acute stress on the sexually-dimorphic ventral subiculum circuitry and identify sex-specific synaptic and behavioral adaptations. Critically,...

New publication from Dr. Carley Miller in a collab with Dr. Kevin Beier, and Chris Li (at UCI)! Acute stress triggers sex-specific changes in the ventral subiculum. They’re unexpectedly driven by distinct signaling pathways! Check it out 👉 tinyurl.com/3fvkumuy

A bar graph. On the left side is a bar showing that Republicans are cutting $930 billion from Medicaid. On the right side is a bar showing that Republicans are giving $910 billion in tax breaks to corporations under their budget bill, paid for by gutting Medicaid.

Republicans may lie about what's in their budget bill but the numbers sure don't.

Really excited to speak at the Canadian Conference on Epigenetics. Join us in beautiful Banff in November 👇🏻

Pope Leo condemns US bombing Iran

Don’t forget to register to the seminar on June 27 and July 25:

GESTALT - Seminar Series

June 27 - 2025: Dr. Fei Chen
July 25 - 2025: Dr. Hanchen Wang

Please visit the Seminar Series Webpage for more information and registration: globalspatial.org/seminar-seri...

Only two years left of world’s carbon budget to meet 1.5C target, scientists warn Breaching threshold would ramp up catastrophic weather events, further increasing human suffering

We’re wasting the remaining carbon budget on war and AI.

Kupffer cell programming by maternal obesity triggers fatty liver disease Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.

We are SO EXCITED to share our story @nature.com:
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Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring.
This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease.
👉 Read here: rdcu.be/erD3b

Come and join us! Start your group at Karolinska Institutet @ki.se!