Mona Johannessen

Thinking about a postdoc in microbiome science?
Our lab at the MPI for Biology (Tübingen) builds on the culture I established at Cornell: collaborative, creative, and internationally diverse. Postdocs lead their own projects with secure funding. Join us!
#PostdocJobs #HostMicrobe #AcademicJobs

Nasal Staphylococcus aureus carriage promotes depressive behaviour in mice via sex hormone degradation - Nature Microbiology Nasal colonization by Staphylococcus aureus is linked with depression in a human cohort and shown in a mouse model to cause decreased serotonin and dopamine in the brain.

#NewResearch

Nasal colonisation by S. aureus is linked with depression in a human cohort and shown in a mouse model to cause decreased serotonin and dopamine in the brain

#MicroSky #Depression

www.nature.com/articles/s41...

Congrats, @ronimiah.bsky.social with your newly published work.

Fishing out AIEC with FimH capturing microgels for inflammatory bowel disease treatment - Nature Communications Inflammatory bowel disease (IBD) is a chronic immune-mediated condition. This study presents a drug-free treatment strategy for IBD that targets bacterial adhesion, utilizing mannan oligosaccharide-lo...

New in Nat Comm

Pathogenic E. coli use protein FimH to grab onto the gut lining

New microgels mimic the mannose binding sites—acting as “decoys” to drag bacteria away and protect the intestine in IBD

Adherent-invasive E. coli (AIEC), enriched in Crohn’s disease, are a key target for this strategy

Good opportunity here to work with a super talented new PI.

Job opportunity Postdoctoral Researcher (m/f/div) in Gut Microbiome Metabolomics at Leibniz HKI Jobportal Wissenschaft/Forschung in Jena

We’re hiring a Postdoc in Gut Microbiome Metabolomics!

Help us decode microbial metabolism and its impact on human health @leibniz-hki.de , Jena 🇩🇪

🔗 jobs.hki-jena.de/jobs/Postdoc...

Regulation of airway fumarate by host and pathogen promotes Staphylococcus aureus pneumonia - Nature Communications This study reveals how the pathogen Staphylococcus aureus adapts to the lung microenvironment, rich in host metabolites fumarate and itaconate, by using a key enzyme, FumC, to support its metabolic fi...

Pleased to share our latest study @natcomms.nature.com! We show that the host metabolites fumarate and itaconate impose selective pressure on Staphylococcus aureus, driving its adaptation via the enzyme FumC. Grateful to all who contributed to this work!
www.nature.com/articles/s41...

Staphylococcus aureus: a model for bacterial cell biology and pathogenesis | Journal of Bacteriology When talking about Staphylococcus aureus, one usually has in mind the diseases that can be caused by this bacterium, ranging from mild skin and soft tissue infections, such as abscesses and furuncles,...

"Among all bacterial species, S. aureus ranks second only to E. coli in the number of scientific publications."
It was a pleasure to contribute to this review, with @pinholab.bsky.social and Friedrich Götz
journals.asm.org/doi/10.1128/...

Staphylococcus aureus exhibits spatiotemporal heterogeneity in Sae activity during kidney abscess development https://www.biorxiv.org/content/10.1101/2025.07.08.663646v1

Staphylococcus haemolyticus is a reservoir of antibiotic resistance genes in the preterm infant gut Staphylococcus haemolyticus is an important cause of sepsis in preterm infants, with gut colonization being recognized as a risk factor for infection. To better understand the diversity of S. haemo...

I am delighted that our manuscript 'Staphylococcus haemolyticus is a reservoir of antibiotic resistance genes in the preterm infant gut' is now published.

www.tandfonline.com/doi/full/10....

Big thank you to all co-authors, particularly @lisalamberte.bsky.social and @halllab.bsky.social

www.biorxiv.org/content/10.1.... New pre-print of the lab in which we dive deep into Klebsiella-macrophage interface. High structural resolution of the lipid A produced by Klebsiella within the Klebsiella containing vacuole governed bt TLR4 signaling. Superb job led PhD student Toby Bartholomew

Assessing the safety of microbiome perturbations Everyday actions such as eating, tooth brushing or applying cosmetics inherently modulate our microbiome. Advances in sequencing technologies now facilitate detailed microbial profiling, driving inten...

(1/6) 🌟 Excited to share our new paper!
Advancing microbiome safety assessments: opportunities, challenges & recommendations 🧫🦠

This work came out of an academic–industry workshop hosted by @microbiologysociety.org in early 2024.

🔗 www.microbiologyresearch.org/content/jour...

Great news for postdocs! 🎉

Looking for your next big career move in microbiology? Explore a range of exciting postdoctoral positions now available on the #FEMSOpportunitiesBoard.

Find your perfect fit and advance your research journey. Apply today👇

buff.ly/CSwBDPl

#CareerOpportunity

Powerful new tool against Malaria (𝘕𝘢𝘵𝘶𝘳𝘦)

Instead of killing mosquitoes, bed nets coated with ELQs (endochin-like quinolones) KILL THE MALARIA PARASITES INSIDE THE INSECTS. Infected mosquitoes land, absorb the drug through their legs, and are rendered parasite-free

www.nature.com/articles/s41...

Secretory IgM regulates gut microbiota homeostasis and metabolism - Nature Microbiology Rainbow trout with depleted secretory IgM reveal interesting insights into the elusive role of this immunoglobulin in maintaining gut microbiota.

🚨 Out now!

Rainbow trout with depleted IgM reveals interesting insights into its role in maintaining the gut microbiota 🐟

#MicroSky #IgM #MicrobiomeSky 🦠

www.nature.com/articles/s41...

I am happy to share our latest preprint, spearheaded by Laura Camus. We show that tyrosin-dependent interactions can foster integration of S. aureus into the nasal microbiome. @cmfi.bsky.social @lmumuenchen.bsky.social
www.biorxiv.org/content/10.1...

Important stuff

Microbes that weather chemo may help cancer patients do the same

Turnbaugh Lab (UCSF) find preTA+ bacteria detoxify 5-FU, reduce side effects

Probiotic supplements to protect patients during cancer therapy?

Works in mouse colorectal cancer model

www.science.org/doi/10.1126/...

Yeah! 7 more years for @cmfi.bsky.social
So many people to thank... We are a fantastic team!

Join us in Tubingen as a Junior Research Group Leader if you do research on #ESKAPE pathogens and infections and are interested in the highly cooperative environment of @dzif.bsky.social‬ and @cmfi.bsky.social ! Please send your application or forward to colleagues!
uni-tuebingen.de/universitaet...

Vacancy Search Results - University of Leicester Recruitment Team View our Latest Vacancies

Interested in phages ?
Want to work as team that will isolate, genome sequence and charachterise 1000s of phage to build a biobank .
Come work with me and Martha Clokie at Leicester

jobs.le.ac.uk/vacancies/va...

Please RT. Post-doc opportunity alert! 💥 closing 5th May.. Come join our team (thelowlab.org) at Imperial, London, working on bacterial secretion systems. The position is funded by the Wellcome Trust.

For more details and to apply please see

www.imperial.ac.uk/jobs/search-...

Chemical strategies for targeting lipid pathways in bacterial pathogens Microbial pathogens continue to plague human health and develop resistance to our current frontline treatments. Over the last few decades, there has b…

If you are interested in lipids in bacteria, check out this awesome new review written by my talented student Alyssa Carter, super postdoc Emily Woods and me. #chembio
www.sciencedirect.com/science/arti...

One of the first antimicrobials blocking a central regulator of bacterial virulence! Great achievement by @cmfi.bsky.social and @dzif.bsky.social scientists Samuel Wagner @hakimb.bsky.social et al

Staphylococcus aureus Bacteremia: A Review This narrative review summarizes current evidence on the epidemiology, pathophysiology, clinical presentation, diagnosis, and treatment of Staphylococcus aureus bacteremia.

New review article on management of S. aureus bacteraemia: jamanetwork.com/journals/jam...

@jama.com @vancefowler.bsky.social #IDSky

Check out the gorgeous Figure which brings together elements of pathogenesis and management: (thread)

Fig 9 from original publication: Bacterial culturability in the stationary phase is dependent on (p)ppGpp-driven GTP depletion. Uncontrolled, high levels of GTP (low ATP) in the (p)ppGpp0 mutant resulted in membrane disorder and decreased PMF. The lower PMF could at least in part be linked to transcriptional downregulation of nucleotide-sensitive genes of the respiratory chain. Maintenance of respiratory chain activity under (p)ppGpp positive/low GTP conditions likely accounts for the observed tolerance of stationary phase cells to bactericidal antibiotics.

Study shows that (p)ppGpp-controlled GTP homeostasis is essential for maintaining the proton motive force.

This ensures #bacterial survival and #antibiotic tolerance.

Study by Andrea Salzer et al. points to new approaches to fight persistent infections:

shorturl.at/HtJ6N

@wolzc.bsky.social

Ever wonder how mouse infection experiments done in two different labs/papers can come up with totally opposite results?

Turns out which anesthetic you choose for your study will dramatically impact mortality and bacterial clearance.

Hunter Gage / Shawn Hannah / Angela Meier
(article link below)

Metabolic modelling reveals the aging-associated decline of host–microbiome metabolic interactions in mice - Nature Microbiology A multi-omics approach reveals host–microbiome interactions in aging in mice.

1/12 Thrilled to share our latest paper on host-microbiome-interactions in aging out in Nature Microbiology @naturemicrobiol.bsky.social, great work led by Lena Best @sci-witch.bsky.social with the Frahm lab within the ITN SmartAge. @crc1182.bsky.social @uni-kiel.de
www.nature.com/articles/s41...

New in Nat Comm

A rapid evolution-tracking system for 𝘒𝘭𝘦𝘣𝘴𝘪𝘦𝘭𝘭𝘢 𝘱𝘯𝘦𝘶𝘮𝘰𝘯𝘪𝘢𝘦 that experimentally tests how this leading MDR threat resists antibiotics and adapts to serum to invade the bloodstream

www.nature.com/articles/s41...

Seks viktige grep i kampen mot antibiotikaresistens Vi kan lykkes, men det krever modige grep fra helsemyndighetene og private finansieringskilder.

Hva om du fikk en infeksjon, men vi hadde ikke antibiotika mot den? Vi trenger disse seks grepene for å holde antibiotikaresistensen på avstand:

www.dagensmedisin.no/antibiotika-...

Role of Formyl Peptide Receptor 2 and Toll-Like Receptor 2 in Skin Barrier Function and Atopic Dermatitis The skin acts as a barrier against external threats and plays an important role in tissue repair. Skin cells, including keratinocytes, sense microbe-associated molecular pattern molecules released by ...

Our new review on microbiome-skin interaction:

Role of Formyl Peptide Receptor 2 and Toll-Like Receptor 2 in Skin Barrier Function and Atopic Dermatitis - Journal of Investigative Dermatology www.jidonline.org/article/S002...