Nikhil Krishnan

the line between "I think this person is going to do something to change the world"

and "there's a 10% chance this person ends up in jail"

is way thinner than I initially thought

Honestly we should ban all social media for one year, a societal “touch grass” reset

I feel like the out-of-pocket newsletter from @nikillinit.bsky.social is like an early Christmas gift each time it lands in my inbox

When everyone brings their +1 you can't do that, it just becomes small talk and people leave early (most of the hashing out happens at 10pm and later)

my lightly disagreeable take is that company holiday parties should not allow +1s

It's not even a cost thing, though that helps. Holiday parties are meant for people at a company to vent, learn what else is happening at the company, and build rapport with people you're currently on projects with

When you work at a startup for the most formative years of your life and you do the math on how much you could’ve made if you had gotten a normal job instead

H/t @healthapiguy.bsky.social for soundboarding this

3) We are seeing companies that take advantage of ubiquitous data transportation standards (e.g. fax) and expanding the use cases by being able to do read anything that comes through, regardless of how the data is structured (e.g. see TennrAI)

2) Voice AI can create information flows where APIs don't currently exist today. Pharmacies don't have APIs that let you see their inventory, but you can call into a pharmacy to ask if they have something in stock. You can do this to essentially create ad-hoc data pulls.

One version of this is AI agents that are scraping data out of EHRs on behalf of providers - and some very big lawsuits being fought around this exact things (Intus v RTZ, PointClickCare v. Real Time Medical Systems)

GenAI tools look at intent on the page instead of where the specific button is + the interface is getting much easier to use to make fixes (e.g. just use a chatbox)

1) Generative AI might actually achieve the future that robotic process automation promised. The issue with v1 RPA was that because it was focused on screen specific features it broke frequently + was too difficult for frontline staff to learn the tools to make fixes themselves.

a few loose thoughts on how AI in healthcare is hacking together interoperability

When are they gonna publish the results from the largest universal basic income experiment of all time: the people working on Alexa

The key is being really good at curation and catering the type of book to a specific audience (eg stripe press targeting tech people)

Each month you get one published book that’s shorter but higher information density, and you pay monthly and get the book no matter what

I always thought there’s was an opportunity for a new publisher focused on 100 page books. This is typically too short of a length for people to buy on a per book basis, so you’d do it as a monthly subscription

(Did)

We did a Friendsgiving where you had to make “weird fusion cuisines”

My entries were gochuchang chicken stuffed with kimchi fried rice + matar paneer in Japanese curry

my toxic trait is whenever someone tells me about a slight inconvenience about their job I tell them they should just quit and start something

totally anecdotal, but I feel like for so many people they met their partner when they were on the fence about going on the date or to an event where they met their partner

I feel like it's something about coming in with low expectations and then being really happily surprised

Sleep health is getting interesting | Out-Of-Pocket The consumer and clinical worlds of sleep are colliding

Full post is here www.outofpocket.health/p/sleep-heal...

new post that I've been working on for a bit

a deep dive into how the world of sleep health is changing

This is a great post about what’s unique about palantir’s culture (good and bad)

Thought this part about shifting respect to people that go in the field was particular good

t.co/07soLk2Ky4

IMO this is one reason why it’s important to have a strong POV on what your culture is - and why it should explicitly dissuade certain people from joining as much as it attracts other kinds of people

Gotta give palantir credit - have chatted with several ex-palantir people looking for their next company to join and they explicitly have mentioned wanting to join another ex-palantir founding team

What’s the big trend happening in your industry?

One thing about the internet town square degrading is I’m learning less about other industries where I might borrow ideas from

So figured I’d just explicitly ask

Waymos are probably going to do more for healthcare than all digital health startups lmao

guy next to me on my flight to SF wearing a Vision Pro - looks like he’s pleasuring the air in front of him

we’re so back

There also is increasingly more research around how your underlying biological rhythm can affect things like how your metabolism functions, which can affect how drugs work and potentially things like insulin resistance.

This can tell us things like whether we’re predisposed to being a morning or night person, which is a big issue when it comes to sleep.

We live in a world designed for only one chronotype, and maybe we should have schools specific to your chronotype (e.g. for night learners).