Tara Lech, PharmD

📢📢NEW research from @jthjournal.bsky.social!

Two new papers were released on stroke risk and prediction in #atrialfibrillation. Whether you’re a clinician or researcher, you won’t want to miss these insights. Visit jthjournal.org to explore this new research. #stroke #afib #af

Who would have thought VTE management could be so much fun!
Thank you @thecurbsiders.bsky.social 🫶🏼
#PharmSky #MedSky #CardioSky #SkyRx #HemeSky
@anticoagforum.bsky.social

#CardioSky #HemeSky #PharmSky #SkyRx #VTE #Thrombosis #AnticoagStewardship

ISTH 2025 Congress Highlights: What You Might Have Missed | Vasculearn Network Key Insights from our Board members, @Alfonso J Tafur and @Tara K. Lech Log in to https://vln.thrombosis.org and check out the ISTH 2025 Community Page for more details & even more presentations not...

💥If you want to see practice changing highlights from #ISTH2025, you can check out the VLN Newsletter vln.thrombosis.org/c/clinical-r...

or log in to the VLN ISTH 2025 Community Page lnkd.in/eyrrr4qZ to see ALL the posts and interact with the community.

I look forward to seeing you there!

vln.thrombosis.org/c/what-s-new...

Vasculearn Network is hosting a Women's Health Support Group May 12th @ 7PM EST

This is a safe & trusted space for patients to ask questions, receive educational resources & feel supported as they learn to VascuLive with their diagnosis

👉Register lnkd.in/esHHKW62

Thank you! I really appreciate you sharing this information 💜

Did you know that NATF has rebranded? Check out the brand new Vasculearn Network: www.google.com/url?q=https:...
Their dynamic site is full of great resources for patients & providers.
I personally love their patient support groups and reading What’s Hot in Clots by @bbikdeli.bsky.social!

Outpatient management of cancer-associated pulmonary embolism: a systematic review and meta-analysis Graphical abstracterj;65/4/2401596/GA1F1GA1Overview of the study. (s)PESI: (simplified) Pulmonary Embolism Severity Index; VTE: venous thromboembolism.

Outpatient management of CAT? Insightful review from @marccarriermd.bsky.social @drdebthrombo.bsky.social & colleagues

publications.ersnet.org/content/erj/...

Excited to share an important new document from ACForum and FWGBD addressing the care of folks with the potential to menstruate (or enter menopause!) or become pregnant. Check it out! acforum.org/web/resource...

Clinical Pharmacist Specialist Anticoagulation Hybrid / Remote (Burlington, MA.) at Beth Israel Lahey Health Learn more about applying for Clinical Pharmacist Specialist Anticoagulation Hybrid / Remote (Burlington, MA.) at Beth Israel Lahey Health.

📢 Calling all Anticoagulation Specialists! Come join our comprehenisve management program. We care for patients on warfarin & DOACs with an emphasis on #Stewardship #Quality and #Equity
Please reach out with any questions
#jobs #hiring #pharmsky #skyrx #anticoagualtion
jobs.bilh.org/job/cambridg...

Agenda Our comprehensive agenda will cover Cardiometabolic Health, Cardiovascular Prevention, Atherosclerosis, Thrombosis, Cardiovascular Dysfunction, Arrhythmias, Valvular Heart Disease and more.

The @medscape.com Heart of Cardiology 2025 conference started yesterday with several stellar presentations! Here are a few key take away points that I’ve been thinking about… www.heartofcardio.com/agenda

Ok, here is the big lesson learned:
💡 When setting up the transfer device the Balfaxar vial MUST be on a solid flat surface so you can push down with force
- We observed team members just connecting the 2 vials, and this led to a loss in the seal & increased transfer times
#pharmRx #SkyRx #PharmSky

Prevalence of discussions around left atrial appendage occlusion as a treatment option in patients on oral anticoagulation experiencing a major bleeding event - PubMed In patients experiencing a major bleed, less than a quarter had documented discussions about LAAO and over a quarter permanently stopped anticoagulation.

💡In this study, < 25% of pts with a major bleed had documented discussions about LAAO & > 25% permanently 🚫 anticoag. Education & shared decision making is vital. These pt are still at risk for embolic events pubmed.ncbi.nlm.nih.gov/39644619/?ut... @gbarnesmd.bsky.social

Drug-drug interactions between direct oral anticoagulants and anticancer drugs: A single center daily practice evaluation of the occurrence, prescriber response, and subsequent thrombotic and bleeding... Drug-drug interactions between direct oral anticoagulants and anticancer drugs: A single center daily practice evaluation of the occurrence, prescriber response, and subsequent thrombotic and bleeding...

I am a big fan of practicle papers! It is great to see how providers are handling these interactions and what the impact on patient outcomes
#PharmRx #Skypharm #Hemesky #MedSky
pubmed.ncbi.nlm.nih.gov/39643974/

A Pilot Study Describing DOAC Level Results and Association With Clinical Outcomes - PubMed <span><b>Purpose:</b> Describe direct oral anticoagulant (DOAC) level ordering and interpretation practices in association with clinical outcomes at a vascular medicine clinic. <b>Methods:</b> This st...

Is anyone routinely checking DOAC levels and changing therapy as a result?

Curious to see what others are doing in practice #SkyRx #PharmSky #MedSky
pubmed.ncbi.nlm.nih.gov/38884944/

🚨 Help needed!

We recently switched to Balfaxar and are having issues with reconstitution.

Any tips or tricks? Nurses are reporting times > 10min which is not ideal.

Thanks!
#PharmRx #SkyRx #PharmSky #MedSky #HemeSky #CardioSky

FirstWord

👀 🚨 FDA denies full approval of Andexanet

Can’t say I am surprised. It will be interesting to see what happens next
#SkyRx #PharmSky #CardioSky #HemeSky

firstwordpharma.com/story/5921956

Direct Oral Anticoagulants: Quick Primer on When to Use and When to Avoid - PubMed Direct oral anticoagulants (DOACs) have transformed the landscape of antithrombotic therapy in the past two decades. However, there is uncertainty about when they should or should not be used for trea...

💡Great for trainees!
#AnticoagStewardship #CardioSky
#MedSky #PharmSky #SkyRx @bbikdeli.bsky.social
pubmed.ncbi.nlm.nih.gov/39557062/

Applying Clinical Risk Scores in Real-World Practice: The CHA2DS2-VASc Score in Atrial Fibrillation - PubMed Applying Clinical Risk Scores in Real-World Practice: The CHA2DS2-VASc Score in Atrial Fibrillation

🌟 Good read on how to apply the CHADSVaSc score in clinical practice @gbarnesmd.bsky.social & #GregoryLip #CardioSky #PharmSky #SkyRx #Afib #AnticoagStewardship
pubmed.ncbi.nlm.nih.gov/39365222/

We *tried* to do a meta-analysis on menstrual bleeding in FXI inhibitor studies - not only is it not an outcome, but hardly any participants were capable of menstruation. We call for action to improve capture of HMB in anticoagulant trials in our latest @jthjournal.bsky.social pub. t.co/c26Y0umzOi

Arrhythmia Challenges in Cardio-Oncology: High-Risk Therapies, Management, and Anticoagulation - PubMed Cardiovascular disease and cancer are the leading cause of mortality in the United States. In 2021, there were 695,547 and 605,213 deaths due to heart disease and cancer, respectively. With novel onco...

🚨 Great teaching article
💡Review of cancer therapies that ⬆️ risk of arrhythmias (Did you know Ibrutinib ⬆️ AF risk by 15 fold 🤯)
💡Rate control typically preferred
💡AC can be challenging in frail, pancytopenic, ⬆️🩸risk pts
💡👀 for DDIs
🌟Tailor therapy
#CardioSky #SkyRx
pubmed.ncbi.nlm.nih.gov/39551561/

#SkyRx

As we migrate to #MedSky, here is some advice @shematologist.bsky.social @gbarnesmd.bsky.social and I put together on how to responsibly leverage social media in the practice of medicine.

Are your patients looking for a safe space to ask questions & receive accurate information about their blood clots?
The Vasculearn Network, offers free monthly virtual support groups for patients with blood clots. Along with focused sessions for:
-Long PE/CTEPH
-Cancer
-Women’s Health
#HemeSky

What do we need to focus on de-prescribing on CVD?
Dr. Schwartz gives a good state of the field. Polypharmacy 💊💊 + age = higher complications & 💊🚫 interactions. Huge need to systematically withdrawal low-value “inappropriate” medications #AHA24 #CardioSky

Looking forward to ISTH 2025!

The CDC and WHO report a 20% increase in measles cases last year, driven by decreases in vaccination.

This equated to 107,500 DEATHS, mostly in young children.

This, in a PREVENTABLE disease.

Can only imagine what that number will be if we get rid of all mandates.

🔊 Recording now available for the #ACForum "Ask the Experts" webinar!
Watch here: bit.ly/3QLuunC

Expert insights & Q&A session on:
🔹Thrombosis & Thrombophilia
🔹Valvular Disease & Anticoag
🔹Women's Health
🔹Inpatient Anticoag & Acute Care Management
🔹Outpatient Care
#AnticoagStewardship

#PharmSky