Journal of Cardiac Failure

In the accompanying 🔥editorial, the authors parse the existing data on PA sensors, including the conclusions of this analysis of PROACTIVE-HF.

They opine: "PA sensors are positioned to transform the lived experience of patients with heart failure."

🔗 bit.ly/4pHpLUQ

In this analysis, ambulatory hemodynamic monitoring using seated mPAP, loop diuretic up-titration lowered mPAP within days, while down-titration raised it. ARNI and MRA changes showed variable effects. Real-time hemodynamics may help guide HF med titration!

🔗 bit.ly/4qNO1W5

📣 JCF is now accepting submissions for a Focus Issue dedicated to Innovations in Heart Transplantation, highlighting advances across clinical practice, research, and patient outcomes.

🗓️ Deadline to submit: April 10, 2026

#CallForPapers #HeartTransplantation #Cardiology

Integrated health tech in HF faces real challenges: access gaps📱, privacy/security🔐, workflow disruptions⚙️ & costs 💸. A new SS from @HFSA & @AAHFN highlights solutions: better engagement, interoperability, reimbursement & future directions like automation & ML

🔗 bit.ly/3Z5bgzb

New scientific statement from @hfsa.bsky.social & AAHFN! Integrated health technologies are reshaping HF care💻, from telemonitoring to mobile apps to implantables. Benefits include ⬆️QoL & ⬇️hospitalizations, but success depends on many complex factors.

🔗 bit.ly/3Z5bgzb

Today’s AHF pts are older, obese & multimorbid w/“inflammaging” rather than just pump failure. The latest SotA Review suggests early initiation of 4 GDMT pillars during AHF—and possibly added anti-inflammatory therapy—may improve longer-term outcomes & remission.
🔗 https://bit.ly/3Z2S5Wx

A New Year brings new insights.

The January issue of JCF is here, highlighting timely research and emerging conversations shaping the year ahead in heart failure science.

Start reading 📖 https://onlinejcf.com/current

#HeartFailure #Cardiology

New science 🚨! In the BRING-UP-3 HF study, among ambulatory HF pts in Italy, 65% of HFrEF pt received all 4 GDMT pillars. BBs & RASi/ARNI >90%, MRAs & SGLT2i >80% (though target doses still low). SGLT2i already common in HFmrEF (72%) & HFpEF (50%)!

🔗 https://bit.ly/44jVymK

Despite strong evidence, GDMT remains underused. In this Indian expert consensus doc, using a modified Delphi process, authors propose simplified, patient-profile–based guidance to enable early, safe initiation of the 4 GDMT pillars & improve outcomes in HFrEF.

🔗 bit.ly/4iZB48Q

Tricuspid regurgitation in ❤️‍🩹 HFpEF isn’t benign💡

In 206 pts undergoing invasive exercise testing 🚴‍♀️, moderate–severe TR (vs absent-mild) was linked to ...

⬇️ cardiac reserve — lower peak CO, higher mPAP–CO slope

3.3× higher 5-yr composite HFH or death.

🔗 https://bit.ly/4hZ3YWl

📝 Don’t miss the accompanying editorial!

It dives deeper into this #HeartFailure study — exploring:
📍 Diverse etiologies of high-output HF (HOHF)
💭 How these findings challenge conventional wisdom
🔍 Practical implications for clinical care

🔗 bit.ly/47CV8Kf

🚨 High-output heart failure (HOHF): when more isn’t better!

🤔 Which hemodynamic parameter best predicts outcomes in HOHF?
📉 PCWP, PAPi & PAP → not independently linked to mortality
💡 Elevated cardiac index (CI) = strongest predictor of all-cause mortality.

🔗 bit.ly/47EZC3b

🔎 Can provocative testing during RHC unmask HFpEF?

PAWP with🦵passive leg raise & 🚴‍♀️low-workload exercise help narrow the diagnostic gray zone.

🧠 Great for ruling in HFpEF — less reliable for ruling it out!

#Hemodynamics #HFpEF

🔗 https://bit.ly/4oxDZro

💭 Should invasive pressure-volume loops be incorporated into diagnostic testing for HFpEF?

‼️Half of pts w/HFpEF can be missed w/RHC even w/exercise! And diagnostic scores for HFpEF have limited sensitivity.

But invasive LV pressure-volume loops can help!

🔗 https://bit.ly/47BRuAu

Your next look at the latest heart failure research is here. 🫀

The latest issue of the Journal of Cardiac Failure is now live and ready to be explored.

View the full issue ➜ https://onlinejcf.com/current

#HeartFailure #JCF #AcademicMedicine

🚨Can Assisted Aortic Pulsatility Index (API) help guide weaning from IABP?

📊 Assisted API = (Assisted SBP – Assisted DBP) / PCWP

💡 Original research in JCF's Hemodynamics Focus Issue shows assisted API is a sensitive & specific predictor of successful device weaning.

🔗 https://bit.ly/4oZUa0l

Pacemakers in HFpEF = more than a marker⚡

HFpEF+PM pts had ...
Worse biatrial/ventricular function
⬇️exercise reserve
⬆️HFH/death (HR ~ 1.8 vs no PM)

Mechanistic insights demonstrating that pacing may compound mechanical & chronotropic limitations.

🔗 https://bit.ly/4peKkYR

Final Call for Submissions! 🚨
Focus Issue: Infiltrative & Inflammatory Cardiomyopathies

Your research belongs here. Submit to #JCF’s upcoming Focus Issue.

Learn More: bit.ly/46gZVRq

📆Deadline: Dec. 8, 2025

#CardioTwitter #CardiologyResearch #CallForPapers #Hemodynamics #AcademicMedicine

New science 🚨!

Simple 1-point mPAP/CO ratios during 🚴‍♂️CPET w/echo predict outcomes in unexplained dyspnea—matching complex slope methods but with 🔥 higher reproducibility!

Practical tool for assessing #ExercisePH 🫁🫀

#Hemodynmaics #ExerciseTesting #CPET

🔗 https://bit.ly/4patiuW

Submit Now - Deadline is Approaching!
Focus Issue: Infiltrative & Inflammatory Cardiomyopathies

Share your insights. Elevate the field. Publish early 2026 with #JCF.

Topics: bit.ly/46gZVRq
📆Deadline: Dec. 8, 2025

#CardioTwitter #HeartFailure #CardiologyResearch #CallForPapers #AcademicMedicine

The must-read editorial that accompanies this research breaks down the article, and also asks an unresolved question⁉️: should an ICD be implanted *after* LVAD placement in patients who do not already have one?🤔

🔗 bit.ly/48Y9BBC

Benefits of ICDs & CRT-Ds⚡️ in HM3 LVAD pts is uncertain.

This analysis of the MOMENTUM-3 trial showed that the presence of these devices was not associated with ⬆️survival, quality of life, or functional capacity in HM3 LVAD pts.

🔗 bit.ly/43c3HZW

Deadline Approaching!
Focus Issue: Infiltrative & Inflammatory Cardiomyopathies

Your work can drive discovery. Submit to #JCF’s 2026 Focus Issue.

Explore Topics: bit.ly/46gZVRq
📆Deadline: Dec. 8, 2025

#CardioTwitter #HeartFailure #CardiologyResearch #CallForPapers #AcademicMedicine

Accompanying this research is an 🔥 editorial by Drs. Thomas Cascino & @gbarnesmd.bsky.social that analyzes the article & advocates for a systematic evaluation of disparities to enhance care in HF.

🔗 bit.ly/3JvsFgi

Effective communication📢 is key in 🫀 Tx!

This article analyzed outcomes of non-native English-speaking (NNES) recipients vs native English-speaking (NES) recipients, and found that there were no diff in 1y & 5y post-HT outcomes📈 between the 2 groups.

🔗 bit.ly/4qGEzEP

🖥️ AI can play a key role in prev, early detection & treatment of HF, driven by advancements like multimodal LLMs. But challenges like data privacy, system integration, clinician trust & fairness/bias need to be addressed.

Learn more in this Review: https://bit.ly/4oQyuUr

Also, don’t miss the accompanying 📜editorial comment which highlights the urgent need for strategies to promote equitable and risk-aligned HF care within the VA system & across the broader health care landscape.🏥

🔗 bit.ly/43fznh7

In this VA study, the rates of early 🫀follow-up after HFH were low overall & were only modestly associated w/mortality risk at discharge.

Increasing the visit rate after HFH should be evaluated as a mechanism to improve outcomes after HFH!

🔗 bit.ly/493maeW

🧵

Also check out the accompanying editorial - Equip. Engage. Empower.

It talks about how to better center LVAD patient values in care conversations.

✔️From pre-implantation to long-term support, values-based tools are essential

🖇️ bit.ly/4hgGiwo

​Don't miss this new study on LVAD-supported patients & caregivers.

It identified ⚡8 facilitators & 🚧 7 barriers to values discussions with clinicians following implant.

🫶 It promotes elicitation & incorporation of patient and caregiver values into care

🖇️ bit.ly/48w3ILI