André F. S. Amaral (@andrefsamaral) — Bluesky Profile

8 hours ago

Alcohol consumption and small airways obstruction

Alcohol consumption and small airways obstruction - CHEST journal.chestnet.org/article/S001...

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6 days ago

📢 @europeanrespsoc.bsky.social Group 6.1 members

🤷 Join our online meeting and listen to Ruwan Thilakaratne talk about "Associations of metal mixtures in early pregnancy with lung function and asthma in mid-childhood in Project Viva"

🗓️ Tomorrow, FRIDAY, 6 March, 4.00 PM (UK time)

ℹ️ Join the Group

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1 week ago

There is just one month left to apply for an ERS Short-Term Research Fellowship.

Don’t miss this opportunity to conduct a project and explore research techniques at an institution outside of your home country.

Apply now: https://bit.ly/47jNJzA

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1 month ago

📢 @europeanrespsoc.bsky.social Group 6.1 members

🤷 Join our second online meeting and listen to Dr @chloebloom.bsky.social talk about "Pregnancy, asthma and exacerbations: a population-based cohort"

🗓️ Tomorrow, FRIDAY, 6 February, 10.00 AM (UK time).

ℹ️ Join the Group

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1 month ago

"Lung capacity is a determinant of cardiovascular disease and myocardial infarction"
doi.org/10.1186/s129...

We now need to:
- understand why?
- what mechanisms underlie this relationship?

We also need to investigate this in non-European populations.

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2 months ago

📢 @europeanrespsoc.bsky.social Group 6.1 members

🤷 Join our first online meeting and listen to Dr Daniil Lisik talk about "Respiratory symptom trajectories in childhood and lung function in early adulthood"

🗓️ Tomorrow, FRIDAY, 9 January, 12.00 PM (UK time).

ℹ️ Join the Group

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4 months ago

At the heart of vulnerability: plaques, patients and the pursuit of purpose Join us for Professor Ramzi Khamsis' Imperial Inaugural lecture.

Join us on 10 December for Professor Ramzi Khamis' inaugural lecture, exploring the hidden risks of heart disease, focusing on vulnerable arterial plaques, emerging diagnostic tools, and advances in patient care. 🫀

Don't miss out, register now ⤵️
www.imperial.ac.uk/events/19982...

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7 months ago

Could our findings have an impact on home spirometry and low resource settings?

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7 months ago

Interested in lung function and its measurement in epidemiological studies?

Check this paper out 👇
"Concordance between FVC and FEV6 for identifying chronic airflow obstruction and spirometric restriction in the Burden of Obstructive Lung Disease (BOLD) study"
doi.org/10.1136/bmjr...

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8 months ago

Quality of life associated with chronic cough in the multinational burden of obstructive lung disease (BOLD) study: a cross-sectional study The findings indicate the need for increased awareness about chronic cough and its association with reduced quality of life, particularly in low- and middle-income countries.BackgroundChronic cough (CC) can impact daily life and persist for years. Its prevalence varies globally, but whether quality of life in CC also varies across regions is unknown. This study investigates the association of CC with mental and physical component scores of the 12-item Short Form Health Survey (SF-12) reflecting health-related quality of life in a multinational study.MethodsWe analysed data from 19 642 adults (≥40 years), recruited between Jan 2, 2003 and Dec 26, 2016 in 31 sites (25 countries) from the Burden of Obstructive Lung Disease (BOLD) study, who provided information on quality of life and CC. We assessed associations using linear regression, adjusted for confounders, and used random-effects meta-analysis to examine differences by sex and gross national income.FindingsOverall, lower mental (−1.42, 95%CI −2.11 to −0.73; I2=32.7%) and physical (−2.59, 95%CI −3.22 to −1.96; I2=40.1%) health scores were associated with chronic cough. The association between physical health score and CC did not materially differ between sexes or gross national income. In males, physical health seems to be more affected by CC amongst those living in low- and middle-income countries (LMICs). In females, mental health also seems to be more affected by CC amongst those living in LMICs.InterpretationCC impairs health-related quality of life globally. However, it appears that physical health in males and mental health in females living in LMICs may be particularly affected by CC. These findings support the need to consider CC as a target for specific interventions to attenuate its burden on health and the economy.Funding.Wellcome Trust (085 790/Z/08/Z)

Interested in chronic cough? Does it affect quality of life? Find out reading
"Quality of life associated with chronic cough in the multinational burden of obstructive lung disease (BOLD) study: a cross-sectional study"
doi.org/10.1183/2312...

#respiratory #epidemiology #global #health

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8 months ago

Fibular length and vital capacity in the multinational Burden of Obstructive Lung Disease follow-up study ExtractThe relative association of leg length and total height on lung volumes may be important for the clinical assessment of forced vital capacity (FVC) and for understanding critical periods in lung development. The expected size of the FVC in a healthy person generally takes account of their age, sex and size. Most commonly size has been assessed as standing height or standing height squared. Louw et al. suggested that sitting height gave a better assessment of lung function than standing height. [1] Harik-Khan et al. suggested that differences in sitting height explained the difference in lung volumes in European Americans and African Americans, and suggested that this might be explained by the thoracic height being lower relative to total height in African Americans. [2] Krause et al., in a comparison of Danish and Inuit children, also suggested that a lower height-adjusted Forced Vital Capacity (FVC) in Danish children might be explained by shorter limb lengths in the Inuit children. [3] Gunnell et al. showed an association between leg length and both one-second Forced Expiratory Volume (FEV1) and FVC in the Scottish Midspan study [4].

Lung volume correlates with standing height. Does it correlate also with the length of the calf bone?

Check out the most recent paper of the BOLD study to know the answer:
publications.ersnet.org/content/erj/...

#respiratory #epidemiology

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8 months ago

📣 Call open for 1 Dr Victor Phillip Dahdaleh Graduate Fellowship!

This is an exceptional opportunity to contribute to innovative work in respiratory and cardiac sciences at @imperialnhli.bsky.social.

Includes stipend and full tuition fees (overseas fees covered too!)

🗓️ Deadline: 30 July

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9 months ago

#SER2025 attendees you will see these slides advertising our new open access journal AJE Advances: Research in Epidemiology @ajeadvances.bsky.social As an editor, I’m happy to answer questions about why you should publish with us. Come find me!

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9 months ago

Multi-analyst approaches discussed @dingdingpeng.the100.ci More work required in the epidemiological space is one conclusion

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9 months ago

Krista and I are giving an introduction to Mendelian randomization in Brown 3 starting in a few moments - I will post my slides here after the session #eshg2025

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10 months ago

Andre Amaral on stage behind the lectern giving a talk and presenting slides on a big screen.

It was great to give a plenary session talk on the last day of the ARTP conference! I presented work from my team on the #epidemiology of small airways obstruction and #COPD. Most of the work has been conducted by #PhD students I have and had the pleasure to supervise.

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10 months ago

Imperial College Research Fellowships The Imperial College Research Fellowship (ICRF) scheme is designed for outstanding early career researchers looking for an opportunity to focus on re...

🚨 #Postdoc fellowship opportunity at @imperialcollegeldn.bsky.social. Check it out 👇 #job #research

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10 months ago

Dagitty has online and offline versions and has a package for R: dagitty.net. However, if 'pretty' is a must, then PowerPoint or Inkscape (inkscape.org).

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11 months ago

Quality of life associated with breathlessness in the multinational Burden of Obstructive Lung Disease (BOLD) study: A cross-sectional analysis Evidence of an association between breathlessness and quality of life from population-based studies is limited. We aimed to investigate the association of both physical and mental quality of life w...

#Breathlessness is unpleasant. Is quality of life affected by it? Is this relationship homogeneous across the world?

For answers, check out: "Quality of life associated with breathlessness in the multinational Burden of Obstructive Lung Disease (BOLD) study: A cross-sectional analysis"

#TeamAmaral

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11 months ago

Members of the CHEST Africa study in a meeting room. Some members attended remotely.

I've had a great time working with amazing people in Durban (SA). We've:
- discussed preliminary results of CHEST Africa,
- listened to people with #asthma talk about their experience of living with a disease that still causes stigma in Africa, and
- brainstormed ideas for future projects.

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11 months ago

Become a member of the European Respiratory Society (ERS) and the Epidemiology group of Assembly 6.
www.ersnet.org/the-society/...

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1 year ago

Latebreaker Abstract Submission Form – Society for Epidemiologic Research Username or Email Password Forgotten Password? Remember Me Log In Username or Email Reset Password Log In Name * Email * Affiliation * Username * Password * Δdocument.getElementById( "ak_js_1"…

⌛ Tomorrow is the deadline for Late Breaker abstracts. Don't miss out #EpiSky, submit your abstract here:

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1 year ago

"Nowadays, with the progress we’ve made in diagnosing, managing & treating the cause of cystic fibrosis, children are surviving – often with good health – & they’re growing up to be adults"

Learn more about Prof Jane Davies, whose work has helped transform the lives of people with #cysticfibrosis👇

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1 year ago

#Gender difference? The risk of chronic airflow obstruction associated with bronchodilator responsiveness is greater among women than among men.

Is this association led by #smoking? This association is also present among people who have never smoked tobacco.

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1 year ago

Bronchodilator responsiveness and future chronic airflow obstruction: a multinational longitudinal study Bronchodilator responsiveness testing is mainly used for diagnosing asthma. We aimed to investigate whether it is associated with progression to chron…

In the multinational Burden of Obstructive Lung Disease (BOLD) cohort study, we have found that bronchodilator responsiveness is a determinant of chronic airflow obstruction. This is a hallmark of #COPD.

#TeamAmaral

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1 year ago

#Bronchodilator #responsiveness is the significant improvement of lung function after inhalation of a certain dose of a medication that widens the airways.

Bronchodilator responsiveness is an important component of #asthma diagnosis.

Is this a determinant of future #COPD?

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1 year ago

Description of ERS group 6.1 Epidemiology

If you are a member of the European Respiratory Society with an interest in #epidemiology, consider joining group 6.1 👇

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1 year ago

Using longitudinal data from almost 6,000 adults of the BOLD cohort, which includes sites in low- and middle-income countries, we have shown that the development of diabetes, heart disease and stroke is more likely to occur among people with lower lung volumes.

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1 year ago

Many people with #COPD have cardiovascular disease and diabetes. However, several studies suggest that cardiometabolic diseases are more closely related to low lung volumes than COPD. Most of these studies have been cross-sectional and conducted in high-income countries.

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