Helfrid Hochegger

We are pleased to annouce that a 3.5-year PhD position is available in the GDSC, for a project jointly supervised by Prof. Hochegger and Dr. Oliver. For additional details, inc. candidate eligibility, and how to apply:
www.sussex.ac.uk/study/fees-f...

PhD Studentship: Understanding and Targeting Cell Cycle Control in Cancer at University of Sussex At jobs.ac.uk, you can apply for a PhD Studentship: Understanding and Targeting Cell Cycle Control in Cancer. Explore our diverse range of PhD opportunities today.

Tony Oliver’s and my lab have a joint phd position available to investigate mitotic entry control mechanisms
Please forward to prospective students! Thank you

url.uk.m.mimecastprotect.com/s/ukMTCoy6DT...

A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase reveals a role at metaphase kinetochores - Nature Communications Phosphatase enzymes are challenging to study due to a lack of specific inhibitors. Here, authors develop a chemical-genetic system to inhibit and characterize a major Ser/Thr phosphatase complex, and ...

Delighted to share a chemical-genetic system we developed to rapidly inhibit a serine/threonine phosphatase complex (within secs). This will make it much easier to study #phosphatases. The system is also applicable to other “undruggable” enzymes.

www.nature.com/articles/s41...

Lovely retrospective for Dan Dennett.

Zotero is the way

Thanks to the @simplyoncology.bsky.social guys for this opportunity to talk about everything high grade glioma!

Interesting 🧵 about publishing in Math.

tl;dr: All papers in Math are preprinted. When publishers ask big $ for subscriptions or OA, mathematicians simply say "No thanks, we read these papers already on arXiv." Publishers then force unis to buy Math journals by bundling them with Bio journals.

YouTube video by Lex Fridman Adam Frank: Alien Civilizations and the Search for Extraterrestrial Life | Lex Fridman Podcast #455

Here is my deep dive into Life, the Universe and Everything with Lex Fridman.

Discussions include Astrobiology, Technosignatures, the Physics of Life, Quantum Mechanics and the Philosophy of Science.

Big fun 3 hr + conversation.

www.youtube.com/watch?v=yhZA...

Sure but also lots of ginger and garlic!

Christmas dumplings.

Book of the year for me!

Chromosome Segregation and Aneuploidy Aneuploidy is a hallmark of cancer and developmental disorders such as Down syndrome. Understanding how cells accomplish faithful chromosome segregation and how chromosomal instability (CIN) impacts …

Announcing the next EMBO Chromosome Segregation and Aneuploidy Meeting! Italy 2025. Please register and join us for another exciting and friendly meeting in a beautiful location meetings.embo.org/event/25-ane...

Congrats. That’s great new!

Sunday lunch: Fitattensuppe

The absence of telomerase leads to immune response and tumor regression in zebrafish melanoma Most cancers re-activate telomerase to maintain telomere length and thus acquire immortality. Activating telomerase promoter mutations are found in ma…

Our last study👇- loss of #telomerase drives #cancer #regression through dual mechanisms! In #zebrafish #melanoma, tumors collapse via tumor-autonomous pathways (apoptosis, cell-cycle arrest, differentiation) and nontumor-autonomous #immune rejection.
Go Fish 🐟!
www.sciencedirect.com/science/arti...

favourite podcast series this year: therestishistory.com/48-the-frenc... Fascinating, how history repeats itself!

Scientific Officer - Epigenetics and Genome Stability in Chelsea | The Institute of Cancer Research View details and apply for this Scientific Officer - Epigenetics and Genome Stability vacancy in Chelsea . Salary : Commencement on the salary range is subject to comparable skills and exp...

We are looking for someone to join our lab as a researcher (scientific officer). Advert and information on applying is here: jobs.icr.ac.uk/vacancies/10...
It's a great team and a wonderful place to work!