Neuromics

#proteinpurification #streptag #fplc #faqfriday #streptactin #streptactinxt #chromatographytips | IBA Lifesciences ❓🔍 𝗙𝗔𝗤 𝗙𝗿𝗶𝗱𝗮𝘆: 𝗛𝗼𝘄 𝗰𝗮𝗻 𝗜 𝘀𝗵𝗮𝗿𝗽𝗲𝗻 𝗮 𝗯𝗿𝗼𝗮𝗱 𝗲𝗹𝘂𝘁𝗶𝗼𝗻 𝗽𝗲𝗮𝗸 𝗱𝘂𝗿𝗶𝗻𝗴 𝗦𝘁𝗿𝗲𝗽-𝘁𝗮𝗴® 𝗽𝘂𝗿𝗶𝗳𝗶𝗰𝗮𝘁𝗶𝗼𝗻? A broad elution peak in FPLC means longer run times and more diluted protein, which are less than ideal for down...

Some good tips for our customers working with IBA Lifesciences Strep-tag® products. We distribute them all (www.neuromics.com/iba-lifescie...)

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In their cell models, they found that CAFs secrete DKK1, a protein associated with tumor growth and metastasis, when subjected to chemotherapy treatments for CRC. Their results identified CAF-secreted DKK1 as a major player in resistance to treatment.

DKK1 expression in Neuromics colorectal CAFs when subjected to chemotherapeutic agents.

Researchers from the University of Kentucky utilized our colorectal CAFs (www.neuromics.com/caf115) in a new paper examining how CAFs contribute to chemotherapy resistance.

Learn more: www.neuromics.com/studying-the...

#cancerresearch #colorectalcancer

Very interesting research. Thanks for sharing!

Neuromics FBS beats competitors in both price and quality.

The data speaks for itself. When the National Cancer Institute (NCI) tested our fetal bovine serum (FBS) against that of our competitors in five different cell types, we prevailed. Better yet, our FBS wins on price, too. Why haven't you switched?

Check it out: www.neuromics.com/fetal-bovine...

mRNA covid vaccines spark immune response that may aid cancer survival (New Scientist) | Dr E. Shyam P. Reddy The mRNA covid-19 vaccines seem to have an unexpected benefit: extending the lives of people being treated for cancers by boosting the effectiveness of immunotherapy. An analysis of the records of ne...

Some interesting research findings for your Tuesday

www.linkedin.com/posts/dr-e-s...

Want to understand the tumor microenvironment? Turn to our human primary cancer associated fibroblasts (CAFs). Our CAFs are consistently used in groundbreaking research.

Learn more: www.neuromics.com/fibroblasts-...

#cancerresearch #CAFs

Our antibodies for pain research are some of our top-performing products. Why? They have over 2 decades worth of proven results (www.neuromics.com/pain-researc...)

Mu Opioid Receptor (MOR) staining of Rat DRG.

Happy Friday!

Chinese researchers released a study using our rabbit Mu Opioid Receptor (MOR) antibody. They investigated the epigenetic mechanism by which SUV39H1 and MBD1 coordinate to reduce MOR expression in injured DRG neurons.

Learn more: journals.sagepub.com/doi/pdf/10.1...

Immunostaining of mouse fibro/adipogenic progenitors (FAPs) cultured using Neuromics FBS.

#TBT Earlier this year, we highlighted a couple of customer publications using our Schwann cells and fetal bovine serum (FBS) to make exciting discoveries on our blog.

Learn more: www.neuromics.com/cancer-pain-...

A very instructive post from our friends IBA Lifesciences. Choosing the right Strep-tag® resin can make a major difference in results.

Check out the options: www.neuromics.com/iba-lifescie...

www.linkedin.com/posts/iba-li...

Why the Brain Feels the Beat Better Through Sound Than Touch - Neuroscience News | Neuroscience News Your brain literally feels the beat better through sound. Researchers found that when music is heard—not just felt—the brain locks onto the rhythm, helping us move in sync and making music uniquely po...

Interesting research!

www.linkedin.com/posts/neuros...

Stroke research done with neuromics goat polyclonal antibody to Myelin Basic Protein (cat. GT22104).

New paper from over the weekend!

Scientists from UCLA used our Myelin Basic Protein antibody to study how astrocytes respond to strokes in mouse models.

Check out the paper: www.cell.com/neuron/fullt...

Check out the antibody: www.neuromics.com/GT22104

Brain Cells That Thrive on Uncertainty Help Us Adapt and Learn - Neuroscience News | Neuroscience News Your brain has neurons that love uncertainty. Scientists found cells that activate when outcomes are unpredictable—helping us learn, adapt, and stay flexible. Targeting them could improve treatment fo...

Cool research!

www.linkedin.com/posts/neuros...

They cultured our immortalized CAFs with Renca cells before implanting them in mice to study the immunotherapy. Our selection of CAFs enable all sort of tumor models, including 3D in vitro models and in vivo models.

#kidneycancer #cancerassociatedfibroblasts

When treated with the anti-CTLA-4 antibody (immunotherapy), the CAF-positive mice had a large tumor size. OM-RCA-01 was able to target both CAF-dependent and CAF-independent resistance to immunotherapy in the renal cancer in vivo model.

#TBT Last year, researchers published a study using our immortalized kidney cancer associated fibroblasts (CAFs) to investigate the therapeutic potential of the anti-fibroblast growth factor receptor 1 (FGFR1) monoclonal antibody.

Learn more: www.neuromics.com/our-immortal...

#cancerresearch

Our AlphaBioCoat Solution (cat. AC001) is a very popular collagen-based coating solution. It enhances cell attachment, growth, and differentiation by mimicking in vivo conditions.

Check it out: www.neuromics.com/ac001

Also, after several months on backorder, BioLock Biotin Blocking Solution (www.neuromics.com/2-0205-050) is available again.

Neuromics distributes all of IBA Lifesciences' cutting-edge protein purification products. The Strep-Tag® technology equips researchers with an unbeatable combination of yield and purity.

Learn more: www.neuromics.com/iba-lifescie...

We continue to offer high-quality and consistent defined media, coating solutions, and detachment solutions. Whether you're working with stem cells, sensitive primary cells, or benchmark cell lines, we have options for you.

Learn more: www.neuromics.com/media-cell-c...

After months of waiting, we're pleased to share that IBA Lifesciences' top of the market biotin blocking solution, BioLock, is available again in the US. Neuromics continues to distribute all ... After months of waiting, we're pleased to share that IBA Lifesciences' top of the market biotin blocking solution, BioLock, is available again in the US. Neuromics continues to distribute all of IBA's...

#ICYMI

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Neuromics HRMECs Prove Their Consistency To demonstrate the consistency of our HRMECs, we plated our HRMECs in an 8-well chamber slide. The cells were stained with diluted primary antibodies CD31 and von Willebrand factor (vWF), both markers...

#TBT Our human retinal microvascular endothelial cells (HRMECs) (cat. HEC09) are reliable and consistent. In a blog post from a few years ago, we highlighted the expression of CD31 and vWF in the cells. Furthermore, these cells are frequently published.

Learn more: www.neuromics.com/neuromics-hr...

Mixed neuron/glial cultures stained with Neuromics chicken antibody to NF-H (cat. CH22104).

Looking for consistent and reliable markers for neural cells? That's an area where Neuromics excels. We have a large selection of primary antibodies for this purpose.

Check them out: www.neuromics.com/neuronal-gli...

3D colorectal cancer organoids with Neuromics CAFs

Organoids and other three-dimensional models are gaining prominence in today's research. They provide consistent and complex in vivo-like models. Our human cells are consistently being published in 3D research involving organoids.

Check out our cells: www.neuromics.com/human-cells-...

Upcoming cell culture projects? Stock up on fetal bovine serum (FBS) with Neuromics.

Learn more: www.neuromics.com/fetal-bovine...

Huntington's disease successfully treated for first time One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.

This is a massive breakthrough. #HuntingtonsDisease disease has no cure and 100% lethal.

www.bbc.com/news/article...

Endothelial cells, including Neuromics' primary human brain microvascular endothelial cells, from different vascular beds display heterogeneous mitochondrial network morphology.

#TBT Our endothelial cells shine in diabetes research. Earlier this year, researchers at the University of Glasgow published a paper using our human brain microvascular endothelial cells. They compared the cells' metabolic function across glucose conditions.

www.neuromics.com/more-diabete...

Neuromics distributes BioLock biotin blocking solution from IBA Lifesciences.

After months of waiting, we're pleased to share that IBA Lifesciences' top of the market biotin blocking solution, BioLock, is available again in the US. Neuromics continues to distribute all of IBA's product!

Learn more: www.neuromics.com/iba-lifescie...

When researchers employ our human cells in their drug discovery assays, they consistently get results. A growing trend we're seeing is the use of our cells in 3D models. This is especially apparent in customer-published studies.

Check out all our human cells: www.neuromics.com/human-cells-...

Taiwanese researchers use Neuromics CAFs in 3D ovarian tumor model. | Neuromics posted on the topic | LinkedIn Researchers consistently use Neuromics human primary cancer-associated fibroblasts (CAFs) to report dramatic differences between 2D and 3D tumor models. In a new study, Taiwanese investigators used ou...

#ICYMI

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