@poldresden.bsky.social
We are the Cluster of Excellence Physics of Life (PoL) at TUD Dresden University of Technology @tudresden.bsky.social @dfg.de. Our goal is to unravel the principles underlying the organization of living matter. https://physics-of-life.tu-dresden.de
🎉 And that's a wrap! Thanks to everyone who visited our #conference booth at the DPG Spring meeting @dpgphysik.bsky.social, hosted this year at none other than @tudresden.bsky.social!
🧑🔬We greeted researchers and industry experts alike, showcasing our new flyers, booklets, and microscopy data in VR!
👨🔬🧬 Aktuelle Entdeckungen der Brugues-Gruppe @brugueslab.bsky.social werden in einem neuen spannenden Artikel im LaborJournal @laborjournal.bsky.social diskutiert.
PoL is at the DPG @dpgphysik.bsky.social spring meeting in Dresden. Visit us in Tent C until Thursday afternoon!
Special thanks to the @brugueslab.bsky.social for the cool data on our Apple Vision Pro devices! Come check it out 🤓🎉
We are super excited to see a fellow Cluster of Excellence @tudresden.bsky.social joining Bluesky🦋. Welcome, REC²! 🎉
🎉Congratulations to the Friedrich group at PoL @friedrich-group.bsky.social for a new collaboration published in PRX Life!
Read the paper here: journals.aps.org/prxlife/abst...
Here's a beautiful #microscopy image from our PoL Photo Competition 📸
👨🔬 🔬©️ Image taken by Yogishree Arabinda Panda, PhD student in the Fischer-Friedrich group @fischerfriedriclab.bsky.social
🔍 Caption: A SEM micrograph of a mitotically arrested HeLa cell with visible filopodia membrane reservoirs
⚡👩🔬Electrical signals are key for promoting organ regenerative growth, a new study!
Out now in Science Advances, from the Mateus group @ritamateus.bsky.social at PoL and @mpi-cbg.de along with the lab of Frank Jülicher @mpipks.bsky.social
Read the news here: tud.link/7jzptz
Video:©️ Mateus group
New paper alert!🤩Super proud that our story led by superstar postdocs @liujinghui.bsky.social and @nerlielisa.bsky.social is finally out! We found how electrical signals are key for promoting organ regenerative growth!!! A thread 🧵https://www.science.org/doi/10.1126/sciadv.aec0687
Just in time for Friday, the next image from our annual PoL Photo Competition 📸
👨🔬 🔬©️ This #microscopy image was taken by Shuzo Kato, a PhD student in the Brugués lab @brugueslab.bsky.social @mpi-cbg.de
🔍 Caption: The mitotic spindle in a zebrafish embryo under oxygen depletion (DCX-GFP).
How do cells establish and maintain their individuality with such precision? 🦠 A team led by Jan Brugués at the Cluster of Excellence @poldresden.bsky.social at TUD Dresden University of Technology has uncovered fundamental mechanisms that shed light on this question.
ℹ️ tu-dresden.de/tu-dresden/n...
🎉Exciting new findings out in @nature.com today by the Brugués lab! @brugueslab.bsky.social @mpi-cbg.de
👨🔬 The authors describe how physical instability of the cytoskeleton works with the cell cycle to drive organization in the embryo during early development
Read our press release: tud.link/kctu4s
Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩
@poldresden.bsky.social @mpi-cbg.de
Here's the next submission from our annual PoL Photo Competition 📸
👨🔬 🔬©️ This beautiful image was designed by Shuzo Kato, a PhD student in the Brugués lab @brugueslab.bsky.social
🔍 Caption: A mitotic spindle; acrylic on canvas.
Congratulations to researchers in the group of @anne-grapin.bsky.social, PoL PI and director at @mpi-cbg.de for publishing an exciting new method to create functional acinar cells, opening new avenues for organoid research. 🧫
🎥 Exciting BTS from our new film project!
As we start our new chapter at PoL, we’re creating some films to showcase our cutting edge research, career opportunities, and more..
Here’s a sneak peek of what to expect. We can’t wait to share the films with you, coming soon! 🌱✨
🎉PoL PI Elias Barriga @eliasbarrigalab.bsky.social was recently featured in an exciting news piece about bioelectricity research by Quanta magazine @quantamagazine.bsky.social.
Curious? Check it out below! ⚡👨🔬
🎉New findings in PRX from @fischerfriedriclab.bsky.social at PoL overturn a long-standing belief in biophysics about living systems.
Using AFM, the authors have found that time irreversibility is a better signature of cellular activity than effective temperature
Read our news here: tud.link/wu3t36
New paper out: AFM-tip fluctuations inside the actin cortex reveal that effective temperature can remain unchanged while time-irreversibility/entropy production drop (turnover inhibition). #CellMechanics #ActiveMatter #Nonequilibrium
@poldresden.bsky.social @tudresden.bsky.social
Great story from @brugueslab.bsky.social. Congratulations, especially to @alisonkickuth.bsky.social. It was an honour to serve on the Thesis Advisory Committee! @mpi-cbg.de @poldresden.bsky.social #stuffthatmatters
Die mechanische Ratsche: Forscher:innen vom Exzellenzcluster @poldresden.bsky.social haben einen neuen Mechanismus der Zellteilung entdeckt. 🧫 Die in @nature.com veröffentlichten Ergebnisse zeigen, wie die Teilung über einen "Ratschen"-Mechanismus vorangetrieben wird.
ℹ️ tu-dresden.de/tu-dresden/n...
Really happy to see my PhD first-author paper published in @nature.com! I’m very grateful to have worked with such a great team. Huge thanks to Urša Uršič, Michael Staddon, and Jan Brugués, as well as the @brugueslab.bsky.social, and the @poldresden.bsky.social and @mpi-cbg.de community!
Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩
@poldresden.bsky.social @mpi-cbg.de
Image ©️ Alison Kickuth @alisonkickuth.bsky.social
🎉Exciting findings out today in Nature @nature.com from the PoL group of Jan Brugués @brugueslab.bsky.social! The authors describe a new mechanism driving cell division during early development in #zebrafish, fundamentally altering our view of the process.
Read the press release: tud.link/2s3bxj
🏋️Our review on how to build muscle is out in
@biophysicalreviews.bsky.social: The Physical Basis of Sarcomere Assembly. We critically review past models and discuss a new mechanism that unifies past ideas, suggesting tension-driven self-organization. With
@frankschnorrer.bsky.social & Kolley-Köchel
Continuing the entries from our annual Photo Competition 📸
👨🔬 🔬©️ This #microscopy image was captured by Arthur Boutillon from the Campàs lab @campaslab.bsky.social
🔍 Caption: Rhodamine dextran diffusing between cells, labelling extracellular space, in embryonic zebrafish.
Researchers from @merihuchlab.bsky.social, together with colleagues from @labshevchenko.bsky.social and clinicians from Dresden and Leipzig developed a patient-specific human periportal liver assembloid. Publication in @nature.com. Full news: www.mpi-cbg.de/news-outreac...
Onto the next submission from our annual Photo Competition! 📸
👩🔬🔬©️ This #microscopy image was captured by Marie Jagemann, a 'Physics of Life' MSc student
🔍 Caption: Early zebrafish embryos forming the shape of an adult fish.
Here's another beautiful submission from our annual Photo Competition 📸
👨🔬©️This #microscopy image was captured by Jaime Espina from the Barriga lab @eliasbarrigalab.bsky.social
🔍 Caption: A cell cluster performing durotaxis and exhibiting differences in tubulin stabilization (nuclei shown in blue).
We’re excited to share the entries from our annual Photo Competition 📸
👨🔬 Here's a stunning image by Shuo-Ting Yen from the PoL Campàs lab @campaslab.bsky.social
Caption: Developing zebrafish retina from the zebrabow line, captured with a Zeiss LSM980 confocal microscope using an oil paint filter.