Sean Ryder

Sean Ryder

@seanryderphd.bsky.social

RNA biochemist turned CRISPR geneticist. Professor and Vice Chair in Biochemistry and Molecular Biotechnology at UMass Chan Medical School. Proud parent of two wonderful children. Believer in compassion, kindness, mutual respect

327 Followers 412 Following 176 Posts Joined Nov 2024
1 week ago
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Please register at this link: forms.office.com/Pages/Respon...

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1 week ago
Microsoft Forms

The RNA Society and the Alliance for mRNA Medicines (AMM) are collaborating on communication and advocacy training for members. Please fill out this form if you would like to attend on March 6, 2:00-3:00pm ET.

forms.office.com/Pages/Respon...

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2 months ago
Professor Sean Ryder: It's time to rock that ribonucleic acid Can you rock the RNA? Professor Sean Ryder of UMass Chan Medical School's got a book for you.

Sean Ryder, PhD, spoke with Worcester Magazine about RNA therapeutics and how they may treat a wide variety of health conditions in the future and the quest to separate facts from misconception: direc.to/oinD

#RNA @seanryderphd.bsky.social @rti-umasschan.bsky.social @worcestermagazine.bsky.social

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4 months ago
A conserved triple arginine motif in OMA-1 is required for RNA-binding activity and embryo viability A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms

I am grateful to share that the latest research paper from the lab is now published in RNA. This work was a wonderful collaboration with Francesca Massi’s lab. Please join me in congratulating co-first authors Asli Ertekin and Sharon Noronha.

rnajournal.cshlp.org/content/31/1...

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4 months ago

Thanks Aaron!

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4 months ago
A professor stands at a podium in a Universalist Church, speaking to audience members in the pews. The cover of a book titled Everyday RNA: The future of RNA medicine. The cover is pink with a single stranded nucleic acid cartoon. The professor signing a copy of his book at a podium in a church. A projected image on a TV screen of the title slide that reads "GAIN presents "From Cows to COVID (And Beyond): A brief history of vaccines" by Sean P. Ryder, Ph.D.

I gave a public educational seminar on the history of vaccines yesterday sponsored by @gain-indivisible.bsky.social. I encourage all scientists to give public educational seminars a shot. You’ll learn something and you will be surprised (in a good way) by the people you meet.

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4 months ago
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My son (the wizard), myself, and @repmcgovern.bsky.social at the #Worcester #NoKings rally put on by @gain-indivisible.bsky.social. It was a glorious day to fight the power with my people. Representative McGovern is my guy, 100%. He shows up and he tells it like it is.

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5 months ago
Figure 5: Germ layer patterning defects in the mex-3 Δ3′UTR mutant. (A) mex-3 RNAi results in dead embryos with a large expansion of muscle lineage cells (mesoderm, yellow). Control animals develop normally, with all three germ layers present and appropriately patterned. Cytoplasmic (C) green represents GFP::MEX-3 protein, nuclear (N) green indicates endoderm, nuclear (N) yellow indicates mesoderm and nuclear (N) red indicates ectoderm. (B) At elevated temperature, the mex-3 Δ3′UTR mutants form all three germ layers, but patterning appears defective with a moderate expansion of muscle lineage cells (yellow). (C) Fraction of embryos that appear normal versus abnormal binned as in Fig. 4. The genotype and the temperature of growth are shown. CTL is a control for the germ layer background (strain OD1854). All sample sizes and statistical test outcomes are listed in Table S3. Scale bars: 10 μm.

MEX-3’s untranslated region helps worms beat the heat

This Research Highlight showcases the work from Sean Ryder (@seanryderphd.bsky.social) and colleagues:

journals.biologists.com/dev/article/...

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5 months ago
Sean Ryder and research group, including first author Hannah Brown. Picture shows seven people with their hands up and/or doing jazz hands in a hallway.

To learn more about this work and the people behind it, we spoke to first author Hannah Brown and corresponding author Sean Ryder @seanryderphd.bsky.social, Professor and Vice Chair for Outreach, Biochemistry and Molecular Biotechnology @umasschan.bsky.social

journals.biologists.com/dev/article/...

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5 months ago

Help protect our hard-working federal employees at the NIH

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5 months ago

I am not ok with this

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5 months ago
Everyday RNA

Copies of "Everyday RNA" are arriving in the US. I ordered 30 copies—they arrived at my house yesterday. If you haven't pre-ordered a copy, your best bet is to order directly from World Scientific Press . The online retailers won't get them until later.

www.worldscientific.com/worldscibook...

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6 months ago
Everyday RNA

Amazon Rankings:
#1 New Release in Biotechnology (#3 overall)
#2 New Release in Medical Research (#25 overall)
#3 New Release in Genetics (#10 overall)
I have been assured by the publisher that it will be available in the first week of October.

Thank you all for pre-ordering!
everydayrna.com

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6 months ago
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Why a rare blood cancer has become a testing ground for cancer drug innovation A model of innovation

In 2013, my father lost his life to multiple myeloma. Now, a variety of new treatment options are extending myeloma patient lives for years if not decades. It's been amazing to watch. Support the the NIH, fight back against RFK, and protect academic research.

www.fastcompany.com/91388585/

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6 months ago
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Revisionism in the Wake of Covid A dialogue confronting the premise of revisionist efforts to diminish the pandemic's severity and dismantle public health institutions.

There’s a book from political scientists Macedo and Lee that claims the COVID-19 pandemic was not as much of a threat to public health as was supposed, calling into question the role of expertise.

Here, an excellent corrective to that erroneous position:
joshuasweitz.substack.com/p/revisionis...

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6 months ago
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Newsweek is reporting the RFK plans an outright ban on mRNA vaccines in the United States within a few months. That's a huge mistake. Please, speak out against those who would derail the most promising technology to curb virus spread since Charles Maitland and cow pox.

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6 months ago

Thanks Aaron! I hope you enjoy it!

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6 months ago
A book cover with a strand of RNA on a pink background, with the title, authors name, and publisher.

I did a thing. I wrote a textbook about #RNA. I wrote it so that those without formal science training could understand what RNA is and how it is used in medicine. It releases in the US and Europe on September 8th. www.worldscientific.com/worldscibook...

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6 months ago

Horrible news!

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7 months ago

Very timely review for those of you who have been following all of the recent developments in this area... also @cp-trendsbiochem.bsky.social why can't we share via bsky directly from the article???

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8 months ago

Sounds like another nazi to me.

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8 months ago
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Announcement of Expanded Screening and Vetting for Visa Applicants - United States Department of State The State Department is committed to protecting our nation and our citizens by upholding the highest standards of national security and public safety through our visa process.  A U.S. visa is a privil...

www.state.gov/releases/off...

To facilitate this vetting, all applicants for F, M, and J nonimmigrant visas will be instructed to adjust the privacy settings on all of their social media profiles to “public.”

I am not ok with this!

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8 months ago
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Hi, it’s Meg again. Brad is still in ICE custody.

We are grateful to the many friends, supporters, and allies who have gathered in Federal Plaza.

Together we are standing up for those with no voice.

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8 months ago
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Hi, this is Meg Barnette, Brad's wife.

While escorting a defendant out of immigration court at 26 Federal Plaza, Brad was taken by masked agents and detained by ICE.

This is still developing, and our team is monitoring the situation closely.

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8 months ago
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Grateful to share a microphone and a stage with one of the very best Congresspersons in the nation, @repmcgovern.bsky.social! This was at the #Worcester #NoKings rally. 2000+ energized attendees at the rally behind city hall. #GAIN

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8 months ago

Just get rid of this guy already. I'm sick of his face.

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8 months ago
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Tomorrow we stand together. We stand for democracy. We stand for basic human decency. We stand so that our great Republic will not fall.

We need you. We need ALL of you. Stand with us. Together we are Indivisible. Together we will have liberty and justice for all

www.facebook.com/share/1AE97P...

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9 months ago
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Longer video of the forcible removal, detainment, and arrest of Sen. Alex Padilla by the Trump regime during a DHS press conference. Footage provided by Sen. Padilla's team.

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9 months ago

IYKYK

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9 months ago

Yikes!

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