mood
06.03.2026 01:57 β π 3 π 0 π¬ 1 π 0
mood
06.03.2026 01:57 β π 3 π 0 π¬ 1 π 0
London researchers studied 1356 adults from the 1946 British birth cohort and found antibodies to 14 common infections showed little link with Alzheimer related brain changes by age about 70, challenging the idea that common infections drive the disease.
www.medrxiv.org/content/10.6...
154 people with schizophrenia on antipsychotics and found weekly semaglutide improved insulin sensitivity lowered fasting glucose and reduced insulin resistance while helping patients lose about 9.2 kg in 30 weeks.
diabetesjournals.org/care/article...
US Dept of Veterans Affairs study of 606,434 veterans with type 2 diabetes found people starting GLP 1 receptor agonists had lower risk of alcohol, nicotine, opioid, cannabis, and cocaine use disorders and fewer overdoses and SUD related hospital visits.
www.bmj.com/content/392/...
New Hampshire 3 people. A priest, police officer, and state lawmaker still live with long COVID years after infection.
Their symptoms range from brain fog and wheelchair use to gut problems.
newhampshirebulletin.com/2026/03/05/a...
Researchers with 381 people with early Alzheimerβs tested the antibody AL002 that activates the immune receptor TREM2.
The drug changed brain immune signals but did not slow cognitive decline and often caused MRI brain changes.
www.nature.com/articles/s41...
La Jolla scientists, 115,388 single bone marrow cells profiled, found an mRNA vaccine that adds a conserved SARS-CoV-2 membrane epitope to RBD boosted antibodies 8.2x, strengthened T cells, and better protected mice from infection.
www.biorxiv.org/content/10.6...
544 patients. Manila scientists built a low cost SARS-CoV-2 antibody ELISA using a self polymerizing spike peptide, boosting binding by 218% and hitting 83% sensitivity and 97% specificity, or 95% and 100% with a tuned cutoff.
www.medrxiv.org/content/10.6...
Vancouver, Canada, 748 adults found high HKU1 coronavirus IgG after ancestral mRNA vaccination was linked to fewer SARS-CoV-2 reinfections but a higher chance of post COVID symptoms, pointing to Fc driven complement inflammation.
www.cell.com/iscience/ful...
Bergen, 79 participants, found ME/CFS blood shows widespread protein shifts, with fewer intracellular proteins especially from muscle and bone marrow but more secreted immune, vascular, and metabolic signals, including reduced neutrophil proteins.
www.cell.com/cell-reports...
260 participants, found Long COVID was linked to more mild cognitive impairment over 4.4 years, 27% vs 5% after recovery and 1% in COVID negative controls, with about 4 times higher risk and a higher risk of Alzheimer related MCI.
pubmed.ncbi.nlm.nih.gov/41772376/
Beijing National Institute of Biological Sciences, 40 to 43 male mice, a timed dose of cordycepin boosted brain clock rhythms in the PVN, restored hormone cycles, lowered inflammation and epigenetic age, and extended lifespan by about 12%.
www.cell.com/cell/abstrac...
Scientists argue Parkinsonβs rates have more than doubled, likely driven by pesticides, solvents, and pollution acting through the gut microbiome and barrier, so prevention should target environmental policy and gut resilience.
www.jci.org/articles/vie...
Stockholm, 41 adults. Karolinska found that 22 people with long COVID after mild infection showed higher default mode network connectivity about 32 months later, yet this did not track with cognitive test scores, fatigue, anxiety, or depression.
www.nature.com/articles/s41...
Norway, 96 people. 48 with long COVID and 48 recovered controls, about 69 weeks after infection, showed no blood signs of brain cell damage or neuroinflammation, and inflammation signals were not significant after correction.
www.nature.com/articles/s41...
USC, 36 mice, found that fecal microbiota from estropausal donors rewired ovarian gene activity to lower inflammation and looked more youth like, raising an ovarian health index and shortening time to first litter.
www.nature.com/articles/s43...
agreed.
03.03.2026 14:49 β π 1 π 0 π¬ 0 π 0
New Haven, 43,067 US adults.
Scientists using the 2022 to 2024 NHIS found long COVID among previously infected adults fell from 19.7% in 2022 to 13.7% in 2024, while recovery rose from 51.2% to 59.7%, with higher risk in women and lower income groups.
jamanetwork.com/journals/jam...
South Korea, 396 adults with long COVID were randomized to 2 weeks of metformin, UDCA, or placebo, and by 8 weeks recovery was similar at 63.6% to 68.2% across all groups, suggesting neither drug improved symptoms beyond placebo.
www.acpjournals.org/doi/10.7326/...
Francis Crick Institute scientists made a glowing OC43 coronavirus that grows like wild type, letting them separate infected from bystander cells and showing inflammation outweighs interferon while nearby uninfected cells switch on cytokines.
www.biorxiv.org/content/10.6...
Montreal 103 participants.
Researchers found long COVID is linked to an altered gut microbiome that sheds tiny bacterial vesicles, loosening the gut barrier and sparking immune and brain inflammation, and these vesicles activated glia in mice.
www.biorxiv.org/content/10.6...
Kids with juvenile systemic autoimmune or autoinflammatory diseases may face higher neurodevelopmental disorder risk, especially with early onset or delayed treatment, so early screening and team care matter.
www.nature.com/articles/s41...
UC Berkeley, 3553 patients with rheumatoid arthritis, those prescribed IL 6 inhibitors had 60% lower mortality and about 58% lower diagnosed Long COVID over 12 months.
Protection appeared strongest when drugs were taken before infection.
www.medrxiv.org/content/10.6...
Hong Kong University researchers, 35 hamsters, found SARS-CoV-2 left viral fragments in nasal tissue for 120 days after live virus was gone, with ongoing inflammation and receptor shifts that may help explain vulnerability after recovery.
www.nature.com/articles/s44...
Scripps Research and MIT, 45 volunteers and 1 dermatitis patient.
By briefly reawakening skin resident memory T cells, a microneedle patch pulled in and sampled rare antigen specific immune cells from blood without a biopsy.
www.nature.com/articles/s41...
University of Michigan researchers review single cell EBV studies and find infection is a patchwork across cell niches and viral programs, shaping immune exhaustion linked to cancers and autoimmunity and pointing to more targeted therapies.
onlinelibrary.wiley.com/doi/10.1002/...
507 person phase 2 trial, researchers found that combining bimagrumab with semaglutide led to 17.8 kg weight loss at 48 weeks versus 14.2 kg with semaglutide alone and 3.3 kg with placebo. The combo cut body fat by 33.7% while largely preserving muscle.
www.nature.com/articles/s41...
University of Helsinki, 547,264 adults.
Obesity raised the risk of severe infections in a clear dose response pattern.
Class III obesity nearly tripled hospitalizations or deaths.
Globally, at least 1 in 10 infection deaths may be linked to obesity.
www.thelancet.com/journals/lan...
Researchers studied 16 people and found those with Long COVID show altered daily cortisol rhythms.
Using modeling, they saw cortisol pulses faded about 31% slower in recovered patients, pointing to disrupted stress hormone regulation in Long COVID.
www.scienceopen.com/hosted-docum...