Learn R for Humanitarian Epidemiology
· An open source platform
· Available in English & French
Perfect for self‑learning, trainings & field support
Boost your analytical skills in real‑world humanitarian settings.
👉 Access the platform: epicentre-msf.github.io/repicentre/
Congratulations @dndi.org on this major milestone! A powerful step forward in the fight against sleeping sickness.
Hospitalised patients with advanced HIV in Kinshasa faced frequent invasive bacterial infections, with different pathogens driving community‑ vs hospital‑acquired cases.
⚠️ High ceftriaxone resistanceand emerging carbapenem resistance raise major concern.
www.sciencedirect.com/science/arti...
📢 HIV clinics in Burkina Faso, Côte d’Ivoire & Nigeria largely maintained ART access during the pandemic — but viral load monitoring was heavily disrupted and didn’t return to pre‑COVID levels a year later. 👇 journals.lww.com/jaids/fullte...
World Childhood Cancer Day
In Uganda, 3,000 children develop cancer each year, but only 1,000 are diagnosed, often too late.
With the MUST, we're working to change this.
🎯 Goal: A locally adapted early diagnosis algorithm to improve care.
👉 epicentre.msf.org/en/our-proje...
Yellow fever & minimum vaccine doses
500 IU works in adults — non inferior to the standard dose.
👶 In infants, it’s different: a Kenya/Uganda study shows 500 IU fails non inferiority.
👉 Adult thresholds ≠ infant thresholds.
www.thelancet.com/journals/lan...
Using surveillance data from MSF’s Bentiu vaccine study, we evaluated the performance of the tests. The Assure RDT showed good sensitivity (86%), outperforming PCR and specificity comparable to ELISA (94.7%).
✅ Supports its use in Hep E surveillance academic.oup.com/jid/article/...
📢 Cancer: A growing challenge across African countries
On #WorldCancerDay, explore our work on breast and cervical cancer in Mali and Malawi, as well as childhood cancer in Uganda
youtu.be/537grgfZU3s
In @malariajournal.bsky.social we report that after ten years of molecular surveillance in Chad, SP-AQ used for seasonal malaria chemoprevention remain largely effective, though rising markers of partial resistance underscore the need for ongoing monitoring.
link.springer.com/article/10.1...
🗓️ Save the Date!
The next Epicentre Scientific Day will take place on 4 June 2026 at the Palais de la Femme in Paris and online.
A special edition celebrating Epicentre’s 40th anniversary 🎉
Programme coming soon — but you can already register here. 👇
epicentre.msf.org/journees-sci...
Fragile and conflict affected settings: New AMoCo findings show post abortion care is mostly satisfactory, but communication, respect and confidentiality remain major gaps—especially for adolescents and women with less education.
@itmantwerp.bsky.social
epicentre.msf.org/en/news/frag...
Lassa fever vaccination strategies
A new vaccine‑impact modelling study shows that targeting adolescents and adults could deliver the greatest health‑economic value per dose
👉 though the most cost‑effective strategy will depend on vaccine price.
www.sciencedirect.com/science/arti...
In Koutiala, Mali, 41% of <5 children referred from community to reference health centers never completed the referral
Main barriers: transport, distance, perceived costs, lack of follow-up.
▶️Strengthening referral systems is critical for timely care.
link.springer.com/article/10.1...
📖 Must-read: AMR in Humanitarian Settings
AMR is a global health threat, yet evidence from fragile contexts is scarce.
MSF’s review highlights research priorities for the most vulnerable:
✅ IPC
✅ AMS
✅ Diagnostics & Surveillance
journals.plos.org/globalpublic...
As cholera outbreaks surge and global vaccine supplies remain strained, WHO prequalified Euvichol-S in 2024 to meet demand faster.
➡️ For the first time, a study assesses its real-world effectiveness in a one-dose regimen during an epidemic in South Sudan.
epicentre.msf.org/en/news/euvi...
How can HIV prevention be made more accessible to the populations most at risk?
In Malawi, Epicentre and MSF are conducting a study to document the introduction of CAB-LA among sex workers, a group particularly at risk of HIV infection.
#VIH #PrEP
epicentre.msf.org/en/news/anal...
On recrute un.e responsable des activités épidémiologiques pour la mission Tchad de MSF France. Vous avez un diplôme en épidémiologie ou en santé publique, postulez ci-dessous 👇🏾
smrtr.io/vWCQ3
Lung ultrasound (LUS) shows promise in TB diagnosis
➡️High sensitivity, comparable to chest X-ray, but lower specificity
✅Valuable where radiography is unavailable
✅a new scoring system developed improves accuracy, but further validation is needed
www.sciencedirect.com/science/arti...
🌍#WorldAMRWeek
Replay our Scientific Day session on Diagnostics for Antibiotic Stewardship:
✔ Avoid inappropriate STI treatments
✔ Why cumulative antibiograms matter
✔ Rapid tests for carbapenemase-producing bacteria in MSF labs
🎥 Watch now: youtu.be/FlwmAVONDuo
How can we better protect children from malaria in highly seasonal regions?
Epicentre is pleased to be part of the Imvacs Project testing an integrated approach: combining the R21/Matrix-M vaccine with Seasonal Malaria Chemoprevention for children in Mali & Burkina Faso.
youtu.be/r2v9EvWQ1JE?...
Just announced at #WCLH2025: WHO treatment decision algorithms could nearly double pediatric TB diagnoses and treatments.
This breakthrough could save thousands of lives—urgent adoption is needed.
epicentre.msf.org/en/news/who-...
Our study in BMJ Global Health assessed three prenatal nutrition strategies in rural Niger to improve maternal health and reduce adverse pregnancy outcomes.
Findings: no significant differences between approacheshttps://gh.bmj.com/content/10/11/e021013
On November 13 at 3 p.m. CET, join writer and advocate for the fight against tuberculosis @johngreensbluesky.bsky.social for a live YouTube roundtable co-hosted by MSF on improving care for children with TB—nearly half of 1.2M cases in 2024 went undiagnosed.
#EndTB
www.youtube.com/watch?v=XBqQ...
Maths in action for malaria prevention @astmh.bsky.social ! 🦟
A mathematical model, using routine surveillance & climate data, helped define the optimal strategy for seasonal malaria chemoprevention in southern Chad @swisstph.ch
#TropMed25
New randomized, controlled trial results @astmh.bsky.social show longer intervals (6 & 12-month) between Euvichol-Plus® may be considered an alternative to the recommended 14-day regimen in adults and children. A promising option amid vaccine shortages and delayed 2nd doses.
#TropMed25 #6469
Come see us at @astmh.bsky.social from November 9 to 13.
Find us at BOOTH #215, where we’ll be joining forces with MSF and @dndi.org
And don’t miss posters and oral presentation which will feature some of our work. #6469 #6169 #6981 #7782
#TropMed25 #ASTMH2025
Doubling rifampicin dosing helps more patients reach therapeutic levels in HIV–TB coinfection.
EFV-based ART slightly - but not significantly - affects rifampicin & isoniazid PK.
➡️ Safety & efficacy of the combined regimen
academic.oup.com/jac/advance-...
In Mali, an ancillary study compares two R21/Matrix-M vaccine formulation —10-dose vs. 2-dose—to simplify logistics, as part of the broader #IMVACS project which aims to evaluate the effectiveness of a new integrated strategy for administering this vaccine.
www.imvacs.org/safli-r21-10/
📹 Modeling to guide humanitarian action
Hugo Soubrier explains how modeling can help MSF make faster and more informed decisions during epidemics such as Ebola in the DRC and hepatitis E in South Sudan.
#HumanitarianAid #Epidemiology #Modeling #MSF
youtu.be/Wfqo8oOYi6U?...
A promising cervical screening strategy for low-resource settings combining:
✅ HPV testing
✅ automated cervical visual evaluation
… to accurately identify women most at risk of precancer (CIN3+).
Data from 9 countries confirm strong predictive power.
academic.oup.com/jnci/article...
