Robert Grosse @ grosselab

Robert Grosse @ grosselab

@grosselab.bsky.social

all things cytoskeleton - nuclear actin dynamics and genome - nucleoskeleton and nuclear organisation - cancer cell invasion and pharmacology @University of Freiburg

1,392 Followers 857 Following 134 Posts Joined Apr 2024
2 days ago
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An extra goodie, where we I tried to see whether Pol II clusters (cyan) are placed in pockets of low chromatin content, connecting via low-chromatin channels to NPC-rich export patches. I suppose both is the case.

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4 days ago
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Acidic pH Restricts Non‐Tuberculous Mycobacteria Replication Different nontuberculous mycobacteria (NTM) species display unique replication profiles in acidic pH in vitro which correlates to their replication within human macrophages. Inhibition of the acidic ...

Very happy to see this out! Great work by @lockwop.bsky.social @crick.ac.uk and first paper on NTMs from the lab! Parise made a set of 12 fluorescently labelled NTMs covering environmental and opportunistic mycobacteria...
onlinelibrary.wiley.com/doi/10.1111/...

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5 days ago

👇🏽👇🏽👇🏽👇🏽👇🏽
We often think of cell identity as the result of biochemical signals, soluble or membrane-bound. Join to the @fnucleosome.bsky.social seminar series if you would like to know more on how nanoscale extracellular topography can directly regulate cell identity in embryonic stem cells.

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5 days ago

just registered

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1 week ago
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Deltaviruses spread through a viral Trojan Horse Hepatitis D-like satellite viruses, known as deltaviruses, have been recently discovered in a wide range of animals. These viruses are thought to expr…

The Trojan Horse is real, and it’s microscopic! 🐴🦠
Our paper is out today in @cellcellpress.bsky.social!
We discovered that deltaviruses physically hide INSIDE helper viruses to sneak into new cells. And to prove it, we had to image them from every angle. 🧵👇

www.sciencedirect.com/science/arti...

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1 week ago
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🚨 Job Alert - Please share! 🙏

Interested in 3D gene regulation in development & evolution? 🤓🧬

💥 Our lab at @cabd-upo-csic.bsky.social is expanding!

We’re recruiting:
✅ PhD students
✅ Postdocs
💻🧪 Experimental or computational backgrounds welcome

👇 Details below

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1 week ago
The wonderful historic city of Marburg

🚨 University Marburg (Germany) is recruiting a W2 Professor of Mol. Pharmacology in the Faculty of Medicine.

Focus areas: Epithelial adaptation in #inflammation, #regeneration, and/or #cancer

stellenangebote.uni-marburg.de/jobposting/0...

#AcademicJobs #Pharmacology #FacultyPosition #cellbio

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1 week ago
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🚨 #postdoc to be hired in the Paluch Lab 🚨

If you know anyone experienced with and, more importantly, excited about nanoscale architecture of #actincortex and super-res & electron #microscopy do encourage them to apply👇

Amazing colleagues, can only recommend 😉

www.cam.ac.uk/jobs/researc...

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1 week ago
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The Crick to co-lead the Equality, Diversity and Inclusion in Science and Health (EDIS) group The Crick will co-lead the Equality, Diversity and Inclusion in Science and Health (EDIS) group with hosts, the British Science Association, supported by a £10 million grant over seven years from Well...

We’re excited to be working with @britsciassoc.bsky.social to co-lead EDIS, a coalition working to improve equality, diversity and inclusion in science and health research.

Find out more about the plans for EDIS's next chapter ⤵️ www.crick.ac.uk/news/2026-03...

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2 weeks ago
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TriRhena Gene Regulation Club Meeting in March 2026.

📍 Location: @igbmc.bsky.social, Strasbourg 🇫🇷
📅 Date: March 18, 2026 | 2:00 PM

🆓 Participation is free of charge, advance registration is required. Register your abstracts for 20-minute research talk.

www.ie-freiburg.mpg.de/gene-regulat...

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2 weeks ago

Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating).

A brief 🧵 (carried over from the old place)

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2 weeks ago

One week left to register to the Bioimage Analysis with AI course in Pasteur!

This June, 1 - 5.

I give a bit more details in the thread below
👇

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2 weeks ago
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Interesting review from the Notani lab on the different functions and regulatory architectures of transcriptional hubs- including #actin; doi.org/10.1016/j.gd...

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3 weeks ago
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Finding one mutation that improves a protein is hard. Finding five that work together is exponentially harder.

Today in @science.org, Hsu and Konermann labs present MULTI-evolve, a lab-in-the-loop framework that does it in just one machine learning-guided round.

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3 months ago
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Actin Counters Geometry to Guide Plant Cell Division - preLights When geometry isn’t enough, actin helps plant cells decide where to divide, ensuring robust tissue patterning

When geometry isn’t enough, actin helps plant cells decide where to divide, ensuring robust tissue patterning. 🌱 #PlantBiology

Goldy & team uncover a central role for F-actin as a cortical landmark.

#preLight by Jeny Jose @umeaplantsciencecentre.se ⬇️ 👀
prelights.biologists.com/highlights/a...

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3 weeks ago
Research Associate - Godlee Group (Fixed Term) We are seeking to recruit a postdoctoral Research Associate with a background in cell biology and interest in infection research to join the laboratory of Dr Camilla Godlee in the Department of

We have an exciting 3-year postdoc position available to study how Salmonella remodels host membrane dynamics.

If you have a background in cell biology and are interested in working on an infection project this could be for you!

Application deadline - 24th February.

www.cam.ac.uk/jobs/researc...

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3 weeks ago
 Cdc42 accumulates in aged cells, and reducing its levels extends life span.Two representative WT cells expressing Cdc42-mCherrySW are shown at selected ages and time points (hr: min) from initial loading. White arrowheads indicate cells during or shortly after cytokinesis, when Cdc42 levels are quantified. Black and red arrowheads denote the same cells at other cell cycle stages and cell death, respectively. Scale bar: 3 µm.

Cdc42 is a small GTPase crucial for #CellPolarity, but how does it contribute to #aging when upregulated? This study shows that the ER-anchored chaperone Ydj1 interacts with Cdc42, enhancing its stability & partitioning during asymm #CellDivision & aging in yeast @plosbiology.org 🧪 plos.io/4qz7WaM

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1 month ago

The bumpy road leads to the nucleus--cool new mechanobiology!

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1 month ago
LinkedIn This link will take you to a page that’s not on LinkedIn

My lab @cri-utsw.bsky.social is looking for a highly motivated postdoct interested in mechanobiology!

We are building a highly collaborative and interdisciplinary team working on how mechanical forces shape immune and cancer cell behavior.

Come do cool science with me!

lnkd.in/gKEXWUGy

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1 month ago
University of Freiburg

PhD opening
Join a collaborative, interdisciplinary project the Excellence Cluster Future Forests @uni-freiburg.de, working on CRISPR/Cas in poplar to understand how trees cope with climate stress.
Apply here: uni-freiburg.de/en/job/00004...
@dompsfr.bsky.social @biologyunifreiburg.bsky.social

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1 month ago
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Happy International Day of Women and Girls in Science! 🧪 Don't forget to send in your nominations for the FEBS | EMBO #WomenInScience Award.

Deadline: 15 May

Read more:
https://www.embo.org/the-embo-communities/febsembo-women-in-science-awardees/nominate-for-the-women-in-science-award/
#award

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1 month ago
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A high-resolution, easy-to-build light-sheet microscope for subcellular imaging An accessible light-sheet microscope delivers subcellular-resolution, multicolor volumetric, and live-cell imaging, lowering barriers to state-of-the-art performance.

In @elife.bsky.social: A high-resolution, easy-to-build light-sheet microscope for subcellular imaging doi.org/10.7554/eLif...

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1 month ago
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Structural biologist Alexey Amunts launches new research lab in Shenzhen ‘Shenzhen adds another dimension; it is a place where ideas do not remain ideas for long,’ Amunts says of new position.

We're launching a research lab at SMART. Shenzhen Medical Academy for Research and Translation is a newly established institute with long-term funding mechanisms for internal and external investigators. At full capacity SMART aims to support up to 400 labs.
www.scmp.com/news/china/s...

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1 month ago
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Apply now! The 2026 call for the EMBO Young Investigator Programme is now open with a deadline of 1 April 12:00 midday CEST. 🧪

More info here:
https://www.embo.org/funding/fellowships-grants-and-career-support/young-investigator-programme/
#LifeSciences #research #funding

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1 month ago

what a great opportunity!

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1 month ago
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IMPRS PhD Program The IMPRS-EBM is an international PhD program that lies at the intersection of Epigenetics, Biophysics and Metabolism. It integrates strategies from molecular biology and biochemistry with biophysical...

Open PhD position – join our lab in Freiburg

Through the IMPRS (Max Planck) program, we are looking for a motivated PhD student interested in signalling, and developmental mechanisms.

Be quick - deadline is tomorrow!

www.ie-freiburg.mpg.de/IMPRS-PhD-Pr...

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1 month ago

That‘s the spirit.

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1 month ago

A permanent position as a research scientist is opened in our team! We look for a plant physiologist with expertise in plant / microorganism interactions to identify plant susceptibility factors to fungal disease. Please forward!

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We have two funded postdoctoral positions available. Topics encompass:

-Next gen light-sheet fluorescence microscopy instrumentation

-Structured illumination microscopy and other approaches to extend the resolution limit.

-Nonlinear microscopy combined with adaptive optics / phase conjugation

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1 month ago
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Full Professor and Chair Laboratory of Biophysics We are looking for a Full Professor in the Biophysics chair group, part of Wageningen University & Research (WUR)

The Laboratory of Biophysics at Wageningen University & Research (NL) is looking for a new chair! Details here: www.wur.nl/en/vacancy/f...

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