Dr. @yarimura.bsky.social brings frogs back to Fred Hutch after a long absence to study the structure of DNA-linked molecular complexes that change during the cell cycle and malfunction in cancer and other diseases. bit.ly/3J8S5Ae
#Celegans peel-1/zeel-1 is one of the best-characterized animal #toxin-antidote systems, but how does it work? @lewsiferase.bsky.social &co show that PEEL-1 co-opts the PMPL-1 to exert toxicity by creating a novel #IonChannel that leads to cell swelling @plosbiology.org 🧪 plos.io/3HfH8LN
Excited to share a recent preprint by Oliver Newsom, where we evaluate the functional contributions of serum for cancer cell proliferation. Inside:
A broadly applicable serum-free media,
Quantitative lipid uptake characterization,
Evidence lipid scavenging > synthesis for cancer cell proliferation.
Huge congratulations @jbloomlab.bsky.social!
In the midst of the dark ages, we MUST retain optimism—keep going, keep publishing, keep talking science, and keep doing fun experiments! Our latest paper on the fascinating TF SKN-1/NRF presents exciting new findings using our one and only #Celegans #genetics #oxidativestress #proteasome
Our latest work on the ever-fascinating skn-1 transcription factor (Nrf1 and Nrf2 for non-worm people).
www.biorxiv.org/content/10.1...
Check out a fantastic @elife.bsky.social article highlighting @yarimura.bsky.social’s MagIC #cryoEM technique - a method using specialized magnetic beads that makes it possible to study the structure of proteins from dilute samples. elifesciences.org/articles/105...
The best part of the week kicks off soon: Friday Afternoon Seminars!
Can’t wait to learn about the latest research from Elyse Christensen in the @nlehrbach.bsky.social Lab and Liberalis Boila in Human Biology’s Kugel Lab. For all our @FredHutch.bsky.social colleagues, join us for two great talks!
