Selected frames of a live-cell imaging time-course experiment. A single cell is shown, co-expressing PEEL-1::eGFP and PMPL-1::mCherry. The nucleus is labeled (“N”). t = 0 is 16 hrs after transfection. Acute swelling can be seen (t = 2 hr 30 min), followed by a transient blob or protrusion (arrow) jetted out by the cell (t = 4 hr 15 min) and later reabsorbed (dotted arrow) (t = 4 hr 20 min). Scale bar = 10 µm.
#Celegans peel-1/zeel-1 is one of the best-characterized animal #toxin-antidote systems, but how does it work? @lewsiferase.bsky.social &co show that PEEL-1 co-opts the PMPL-1 to exert toxicity by creating a novel #IonChannel that leads to cell swelling @plosbiology.org 🧪 plos.io/3HfH8LN
27.05.2025 18:21 — 👍 25 🔁 8 💬 5 📌 2
Excited to share a recent preprint by Oliver Newsom, where we evaluate the functional contributions of serum for cancer cell proliferation. Inside:
A broadly applicable serum-free media,
Quantitative lipid uptake characterization,
Evidence lipid scavenging > synthesis for cancer cell proliferation.
20.02.2025 02:43 — 👍 43 🔁 20 💬 4 📌 1
Huge congratulations @jbloomlab.bsky.social!
15.02.2025 16:56 — 👍 7 🔁 2 💬 0 📌 0
In the midst of the dark ages, we MUST retain optimism—keep going, keep publishing, keep talking science, and keep doing fun experiments! Our latest paper on the fascinating TF SKN-1/NRF presents exciting new findings using our one and only #Celegans #genetics #oxidativestress #proteasome
09.02.2025 22:19 — 👍 5 🔁 1 💬 1 📌 0
Friday Afternoon Seminars (FAS), this Friday 11/22 at 4pm in Pelton.
Elyse Christensen, Lehrbach Lab
A cabal of conserved ubiquitin ligases cooperate to ensure robust protein turnover
Liberalis Boila, Kugel Lab
Epigenetic dysregulation in IDH mutant intrahepatic cholangiocarcinoma
The best part of the week kicks off soon: Friday Afternoon Seminars!
Can’t wait to learn about the latest research from Elyse Christensen in the @nlehrbach.bsky.social Lab and Liberalis Boila in Human Biology’s Kugel Lab. For all our @FredHutch.bsky.social colleagues, join us for two great talks!
22.11.2024 22:28 — 👍 5 🔁 2 💬 0 📌 0
Postdoc in Villeneuve lab, Stanford | PhD in @cphil.bsky.social's Lab, USC. Here for all things meiosis, C. elegans, & science outreach! she/her
Science writer and author of books including Bright Earth, The Music Instinct, Beyond Weird, How Life Works.
Interested in understanding how organisms sense and respond to stressful environments, and why some individuals are more sensitive or more resilient. he/his
Evangelist for the study of evolution in action by everyone.
Pitt Prof | EvolvingSTEM | biofilms | EvMed | genomics entrepreneur (@SeqCoast.bsky.social, @midauthorbio.bsky.social) | ASM President-Elect | exercise addict ~ swim bike run
Assistant Professor of Cell Biology at Harvard Medical School | HHMI Freeman Hrabowski Scholar | Nexus of chromatin, transcription, replication, and epigenetics. farnunglab.com
We study cell polarity and cytokinesis in the fission yeast model system with emphasis on GTPase signaling patterns @BostonCollege. Immigrant. She/her. www.daslabpombe.com
UMich professor who studies resistance and persistence (in plants)
Science and fun from the lab of Tony Hyman at the MPI-CBG @mpicbg.bsky.social. Tweets by Hymanlab members.
https://hymanlab.org/
We advance protein science to accelerate research & improve human health | proteininnovation.org
of the arts and sciences
jeremyhollisdesigns.com
campbelllab.org
Rapid evolutionary dynamics in viruses, cancer and bacteria. Assistant professor at UW Genome Sciences. federlab.github.io
Biologist; Umass Chan Medical School
Computational designer of molecular tools for intracellular signaling. Assistant Professor at UCLA Bioengineering. https://scholar.google.com/citations?user=T_SIIAsAAAAJ&hl=en
We are the Ting Wu Lab @ HMS. Our laboratory studies how chromosome behavior and positioning influence genome function, with implications for gene regulation, genome stability, and disease.
Managed by WuLab members
https://www.transvection.org/home
Postdoctoral Research Fellow @edinburgh-uni.bsky.social
Ageing, molecular biology, and omics, plus attempting science writer 🧬
📷 https://www.instagram.com/bio_bex?igsh=MWI3NXhpbHRjcmd4cw==
Embryologist/ Molecular Biologist
PhD Student Biochemistry, Cell and Molecular Biology
Extracellular vesicles, cilia, polycystins, C. elegans, Barr lab at Rutgers
Associate Professor at the University of Georgia + Associate Director of UGA Institute of Bioinformatics. Marine Biology, Polar Science, Deep-Sea Worms (nematodes!), Environmental Genomics, and Science Writing. Views are my own. http://www.hollybik.com
Profile Pic: xkcd.com/386/ (but you already knew that)
