Graham Dellaire's Avatar

Graham Dellaire

@docdellaire.bsky.social

Cancer biologist, guitarist, would-be evolutionary molecular biologist, bread baker, sometimes coder, amateur photographer, professional microscopist, & gardener. Lab site: https://blogs.dal.ca/dellairelab/

1,479 Followers  |  219 Following  |  1,532 Posts  |  Joined: 27.08.2023  |  2.2579

Latest posts by docdellaire.bsky.social on Bluesky

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Revisiting this gorgeous #StreetMural in #Halifax Quinpool District. I did a selfie too, to provide scale. It’s a biggin’

19.08.2025 15:51 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Colorful mural painted on the side of a building with the likeness of Henrietta Lacks and the words β€œHeLa” and β€œMiddle East” on it.

Colorful mural painted on the side of a building with the likeness of Henrietta Lacks and the words β€œHeLa” and β€œMiddle East” on it.

Beautiful mural honoring Henrietta Lacks painted by Baltimore community members popped up near Hopkins med campus recently.

17.08.2025 13:40 β€” πŸ‘ 519    πŸ” 99    πŸ’¬ 2    πŸ“Œ 4
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a woman is pointing at the camera with the words spitting facts below her . ALT: a woman is pointing at the camera with the words spitting facts below her .

πŸ‘

18.08.2025 18:36 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

A propos this Bleet... bsky.app/profile/joff...

18.08.2025 18:22 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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a man in a pink shirt is running in front of a sign that says ba vi ALT: a man in a pink shirt is running in front of a sign that says ba vi

Yeah... and forest fire fighters don't need to wear masks because, haven't you ever roasted marshmellows - I mean kind of the same vibe #PublicPolicyByVibes

18.08.2025 18:21 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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A new study from @uhn.ca reveals that long-term air #pollution exposure is linked to scarring in heart muscle tissue (myocardial fibrosis), increasing the risk of #HeartDisease. Reducing pollution is vital for heart health.

πŸ”—: www.uhnresearch.ca/news/air-pol...

18.08.2025 15:20 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 1    πŸ“Œ 1
Figure 2. Single-species FLIM using multiple organelle- or structure-selective small
molecules and one fluorophore. a, TCO and BCN derivatives of HAO, Hoechst, and Docetaxel, which localize to the inner mitochondrial membrane (IMM), nucleus, or microtubule network, respectively. b, HeLa cells were treated with HAO-BCN or HAO-TCO and c, imaged by detecting fluorescence intensity (Intensity), average photon
arrival time (Fast FLIM), or phasor analysis (Phasor).

Figure 2. Single-species FLIM using multiple organelle- or structure-selective small molecules and one fluorophore. a, TCO and BCN derivatives of HAO, Hoechst, and Docetaxel, which localize to the inner mitochondrial membrane (IMM), nucleus, or microtubule network, respectively. b, HeLa cells were treated with HAO-BCN or HAO-TCO and c, imaged by detecting fluorescence intensity (Intensity), average photon arrival time (Fast FLIM), or phasor analysis (Phasor).

Single-dye, transfection-free FLIM multiplexing via bioorthogonal chemistry by Alanna Schepartz and team: www.biorxiv.org/content/10.1...

18.08.2025 08:19 β€” πŸ‘ 16    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

And people look at the same sky and come to completely different conclusions and when they don't have an answer, they make πŸ’© up... #SameSame

18.08.2025 15:03 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Fixed it...

18.08.2025 15:01 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Knowing what we know already about forest fire smoke, PM2.5 and both cancer and respiratory health (TL;DR its bad) - why would we risk the health of these brave firefighters by having them maskless. Minimum they need proper particulate and volatile filtering masks not just fire resistant gaiters.

18.08.2025 14:51 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

LEGENDARY movie. #Feels #GENX

18.08.2025 14:44 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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two birds are standing in the water . ALT: two birds are standing in the water .

That intro sounds like techno loons on a moon lake.

17.08.2025 19:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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a man holding a briefcase with the words oh yes written below him ALT: a man holding a briefcase with the words oh yes written below him
17.08.2025 19:44 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Super cool #BrownBinaryDwarfSystem

17.08.2025 19:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Cool! 😎 Is it me (or a possible artifact of the GIF interpolation) but are those two stars sharing plasma between them during their orbit as they circle each other!?🀯

17.08.2025 19:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Have experienced this - the new whole plasmid sequencing offered by many companies now is such a god send.

16.08.2025 11:44 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Meanwhile in Canada… www.instagram.com/reel/DNTiSSL...

16.08.2025 11:37 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Or the possible title of a quirky horror movies about vampire hunters that smoke weed - think Pineapple Express meets Lost Boys πŸ˜‚

16.08.2025 11:27 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Can confirm πŸ˜ƒ

16.08.2025 11:18 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I love the Northern spirit - I wish more of that rubbed off on our politicians. Just get it done and directly address forest management - quit hand-wringing about things higher up Maslow’s hierarchy of needs. If we don’t have shelter, affordable food and clean air and water - nothing else matters.

16.08.2025 11:17 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Please RP.
We are thrilled to announce that our lab’s first preprint is out!
”Whole-genome single-cell multimodal history tracing to reveal cell identity transition”

We report HisTrac-seq, a multiomic single-cell molecular recording platform.
www.biorxiv.org/content/10.1...

16.08.2025 07:15 β€” πŸ‘ 65    πŸ” 35    πŸ’¬ 2    πŸ“Œ 3
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three south park characters are sitting at a table and the text that explains it ALT: three south park characters are sitting at a table and the text that explains it

It’s spelled - β€œKompromat”…

16.08.2025 11:11 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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a woman with purple hair is sitting in a chair and says " dopamine " ALT: a woman with purple hair is sitting in a chair and says " dopamine "

I tell my trainees that if the small wins in the lab or finding out something new doesn’t spark a dopamine hit- don’t be a scientist. Being a scientist is also a lot like being an artist, your work can take years to complete and may not be immediately embraced, you have to love the process /2

16.08.2025 11:03 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

IMO, the #1 personality trait for a successful scientist is perseverance and #2 is a deep (insatiable) curiosity (dopamine!) about the world. After that is luck/serendipity, decent intuition and way down the list is β€œgood grades”, problem solving or some other measure of intellectual capability 1/2

16.08.2025 10:57 β€” πŸ‘ 36    πŸ” 7    πŸ’¬ 2    πŸ“Œ 2

Next another billionaire will suggest gene editing of humans to need less water.

16.08.2025 10:41 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

IMO - $27B is a lot and could be spent on drone development instead. The era of fixed wing manned aircraft being the dominant air support is ending.

16.08.2025 10:40 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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a man with a mustache says " what you joke " ALT: a man with a mustache says " what you joke "

Lazy, but an austerity move likely to avoid penalties. Also more capitulation to the USA to avoid the tariff noose tightening. So much for elbows up.

16.08.2025 10:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Β£17.9 million research grant to discover new treatments for fungal diseases gets underway A team of leading infectious disease scientists from academia and industry have been awarded Β£17.9 million to identify new drugs to treat fungal infections. The Wellcome funded project will see…

The Medical Research Council Centre for Medical Mycology (MRC CMM) seeks a Research Associate to support assay development and drug discovery. news.exeter.ac.uk/faculty-of-h...

Postdoctoral Research Associate Drug Discovery:
jobs.exeter.ac.uk/hrpr_webrecr...

16.08.2025 10:00 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Oldie but a goodie! #NuclearSubDomains #NPD #HowItStarted academic.oup.com/nar/article/...

15.08.2025 18:37 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Congrats! I have been wanting to do expansion microscopy for a longtime but not gotten over the β€œenergy” barrier to do it. It is also hard to get students to commit to protocols that might take months to workup. An MSc of two years just isn’t enough time.

15.08.2025 11:17 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

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