Emmottlab

@biomarkella.bsky.social

Congratulations to Markella Loi from the @emmottlab.bsky.social on winning the Early Career Award for #BSPR2025 and congratulations to @hannahmayging.bsky.social on being the runner

Certificate for a LEAF gold award for the centre for proteome research

The lab got a nice bit of news yesterday! LEAF gold!

MSCA opens €404.3 million call for Postdoctoral Fellowships Postdoctoral Fellowships offer researchers holding a PhD the opportunity to acquire new skills through advanced training and international, interdisciplinary, and inter-sectoral mobility.

We have projects available on single-cell proteomics, including methods development, and applications to antiviral development and resistance. If you have a strong background in proteomics and are considering an MSCA, get in touch! marie-sklodowska-curie-actions.ec.europa.eu/news/msca-op...

Nikolai and his group are based at Northeastern University and have been pioneers in the field of single cell proteomics.

He will talk about the methods his lab has worked on for multiplexed approaches in SCP, including plexDIA

As we get ready for the British Society for Proteome Research annual meeting in Liverpool (July 7-9th), we will start highlighting our amazing speakers.

First is @slavov-n.bsky.social who will talk to us about Biological and technological frontiers for single-cell proteomics.

Rebee and Max selfie in front of microsoc poster

Max looking happy with his microsoc poster presentation

First poster as @emmottlab.bsky.social PDRAs 🥳

#Microsoc25

Emergence of SARS-CoV-2 subgenomic RNAs that enhance viral fitness and immune evasion Coronaviruses can evolve novel transcription regulatory sequences, generating new RNA transcripts during human infection. This study identifies a prevalent subgenomic RNA in SARS-CoV-2, which produces...

First 2025 paper: delighted to have contributed to this paper on the emergence of a new subgenomic mRNA in SARS-CoV-2 from the Bauer lab

journals.plos.org/plosbiology/...

Investigation of Novel Accessory Proteins in the Replication of Infectious Bronchitis Virus at The Pirbright Institute on FindAPhD.com PhD Project - Investigation of Novel Accessory Proteins in the Replication of Infectious Bronchitis Virus at The Pirbright Institute, listed on FindAPhD.com

Another PhD studentship is available for Oct 2025 start! In a collaboration between the @pirbrightinst.bsky.social and us, you will be investigating the role of novel avian coronavirus accessory genes. See here for more details! www.findaphd.com/phds/project...

Deadline 17 Feb, funded for UK only.

BBSRC NWD CASE: Expanding single-cell proteomics into single-cell multi-Omics at University of Liverpool on FindAPhD.com PhD Project - BBSRC NWD CASE: Expanding single-cell proteomics into single-cell multi-Omics at University of Liverpool, listed on FindAPhD.com

The deadlines for our MRC-funded studentships have now passed, but a funded studentship through the BBSRC NWD DLA is now available for Oct 2025 start in single cell mass spectrometry. See findaphd for more details or drop Ed an email.

www.findaphd.com/phds/project...

Reminder - if you are a new PI in UK virology and you aren’t yet registered for RIVR2025 on Jan9-10th in Liverpool, registration closes on December 5th!

If you are a new group leader in virology in the UK and aren’t yet on the RIVR mailing list, get in touch to be added.

Single cell proteomics! 🙋‍♂️

Loading a mass spec and a nanopore in the same day! Thrilled to be learning another omics method in the @emmottlab.bsky.social 🧬

🙋🏻‍♂️

MRC DiMeN Doctoral Training Partnership: Widening the ‘NET’ to identify new treatments for bronchiectasis at University of Liverpool on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: Widening the ‘NET’ to identify new treatments for bronchiectasis at University of Liverpool, listed on FindAPhD.com

The second is primarily based with Dr Helen Wright, and alongside Dr Freddy Frost to study neutrophil NETs and bronchiectasis. We provide training in proteomics and this builds on some of the clinical proteomics we have done to study CF.

More details here: www.findaphd.com/phds/project...

MRC DiMeN Doctoral Training Partnership: Understanding the mechanisms of norovirus replication at University of Liverpool on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: Understanding the mechanisms of norovirus replication at University of Liverpool, listed on FindAPhD.com

The first is based primarily in our lab and builds on our work on coronavirus and norovirus replication in collaboration with Prof Al Darby and Dr Dom Byrne.

More details here: www.findaphd.com/phds/project...

We have two funded PhD studentships available through DiMeN_DTP programme for Oct2025

Standard_2025_127: Understanding the mechanisms of norovirus replication (Dr Edward Emmot)

Standard_2025_71: Widening the ‘NET’ to identify new treatments for bronchiectasis (Dr Helen Wright)

Just to warn we do not have any positions available in our lab- some fraudulent adverts are being circulated on LinkedIn and possibly elsewhere - the link to the lab website is real but all the links below and the details are all fake.

Porcine Sapovirus Protease Controls the Innate Immune Response and Targets TBK1 Human sapoviruses (HuSaVs) and noroviruses are considered the leading cause of acute gastroenteritis worldwide. While extensive research has focused on noroviruses, our understanding of sapoviruses (S...

New paper: Porcine Sapovirus Protease Controls the Innate Immune Response and Targets TBK1.

Work led by Ileana Georgana from the Goodfellow lab

www.mdpi.com/1999-4915/16...

PhD 2 (Rift Valley fever virus RdRP interactome): www.lstmed.ac.uk/study/resear... (led by Alain Kohl lab, closing date Jan 21st, open to both home and international students)

PhD 1 (Expanding single-cell proteomics to multiomics): www.findaphd.com/phds/project... (closing date Jan 15th, open to both home and international students)

PDRA 2 (Coronavirus reverse genetics): Click here to apply for the role of Postdoctoral Research Associate at University Of Liverpool: my.corehr.com/pls/ulivrecr... (closing date being adjusted to Jan 22nd)

PDRA 1 (Viral proteolysis of cellular substrates): Click here to apply for the role of Postdoctoral Research Associate at University Of Liverpool: my.corehr.com/pls/ulivrecr... (closing date being adjusted to Jan 22nd)

These positions are now available to apply for! - see thread below!

The lab is hiring PhD students and PDRAs for 2024 start! Projects going in proteomics/mass spectrometry and virology.

The host interactome of the Rift Valley fever virus RNA-dependent RNA AbstractRift Valley fever virus (Bunyavirales, Peribunyaviridae) or short RVFV is emerging arbovirus that can cause disease and death in humans and animals. There are no drugs to treat infection, and

A second funded PhD studentship is available for Oct 2024 start! - Investigating the interactions of Rift Valley fever virus RdRP. You will be primarily based with Alain Kohl at LSTM, working with us on the LC-MS/MS portions. Deadline Jan 24. www.lstmed.ac.uk/study/resear...

News is now out officially! Hugely grateful for this award which will let us study coronavirus replication, in particular the role of polyprotein precursors over the next 8 years!

Adverts for two new PDRA positions are working through HR and will be up shortly.

news.liverpool.ac.uk/2023/12/01/2...

BBSRC NLD Doctoral Training Partnership: Expanding single-cell proteomics into single-cell multi-omi... PhD Project - BBSRC NLD Doctoral Training Partnership: Expanding single-cell proteomics into single-cell multi-omics at University of Liverpool, listed on FindAPhD.com

Funded PhD student ship in the lab for Oct 2024 start - expanding single-cell proteomics to single-cell multi omics. This is a CASE project in collaboration with Cellenion and SwanseaUni. Deadline Jan 15. For details see: www.findaphd.com/phds/project...

Investigating markers of pulmonary aspiration in bronchoalveolar lavage from children with severe ne... medRxiv - The Preprint Server for Health Sciences

Congrats to Dr Rosie Maher whose preprint on proteomic analysis of pulmonary aspiration from her PhD studies with Rob Benton and Paul McNamara is now available on @medrxivpreprint.bsky.social : www.medrxiv.org/content/10.1...

New paper: The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity

www.cell.com/iscience/ful...

Delighted to have contributed to this work, led by Hazel Stewart from the Firth Lab, and Yongxu Lu!